Current Approaches and Future Perspectives for Nanobodies in Stroke Diagnostic and Therapy

by Larissa Jank, Carolina Pinto-Espinoza, Yinghui Duan, Friedrich Koch-Nolte, Tim Magnus, Björn Rissiek
Published 2019-01-01

In Vivo Blockade of Murine ARTC2.2 During Cell Preparation Preserves the Vitality and Function of Liver Tissue-Resident Memory T Cells

by Björn Rissiek, Marco Lukowiak, Friederike Raczkowski, Tim Magnus, Hans-Willi Mittrücker, Friedrich Koch-Nolte
Published 2018-07-01

ADP-Ribosylation Regulates the Signaling Function of IFN-γ

by Stephan Menzel, Tomas Koudelka, Björn Rissiek, Friedrich Haag, Catherine Meyer-Schwesinger, Andreas Tholey, Friedrich Koch-Nolte
Published 2021-03-01

Astrocytes and Microglia Are Resistant to NAD+-Mediated Cell Death Along the ARTC2/P2X7 Axis

by Björn Rissiek, Joschi Stabernack, Maike Cordes, Yinghui Duan, Sarah Behr, Stephan Menzel, Tim Magnus, Friedrich Koch-Nolte
Published 2020-01-01

Circulating Endothelial Cells as Promising Biomarkers in the Differential Diagnosis of Primary Angiitis of the Central Nervous System

by Milani Deb-Chatterji, Hans Otto Pinnschmidt, Yinghui Duan, Vivien Haeussler, Björn Rissiek, Christian Gerloff, Götz Thomalla, Tim Magnus
Published 2020-03-01

Generation and Function of Non-cell-bound CD73 in Inflammation

by Enja Schneider, Anne Rissiek, Riekje Winzer, Berta Puig, Björn Rissiek, Friedrich Haag, Hans-Willi Mittrücker, Tim Magnus, Eva Tolosa
Published 2019-07-01

Indoxyl Sulfate Affects Glial Function Increasing Oxidative Stress and Neuroinflammation in Chronic Kidney Disease: Interaction between Astrocytes and Microglia

by Simona Adesso, Simona Adesso, Tim Magnus, Salvatore Cuzzocrea, Michela Campolo, Björn Rissiek, Orlando Paciello, Giuseppina Autore, Aldo Pinto, Stefania Marzocco
Published 2017-06-01

Improved Functionality of Exhausted Intrahepatic CXCR5+ CD8+ T Cells Contributes to Chronic Antigen Clearance Upon Immunomodulation

by Kingsley Gideon Kumashie, Marcin Cebula, Claudia Hagedorn, Florian Kreppel, Marina C. Pils, Friedrich Koch-Nolte, Björn Rissiek, Dagmar Wirth, Dagmar Wirth
Published 2021-02-01

A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice

by Marco Er-Lukowiak, Yinghui Duan, Francois Rassendren, Lauriane Ulmann, Annette Nicke, Friederike Ufer, Manuel A. Friese, Friedrich Koch-Nolte, Tim Magnus, Björn Rissiek
Published 2020-12-01

DNA-Encoded Flagellin Activates Toll-Like Receptor 5 (TLR5), Nod-like Receptor Family CARD Domain-Containing Protein 4 (NRLC4), and Acts as an Epidermal, Systemic, and Mucosal-Adju...

by Steven E. Applequist, Shizuo Akira, Jorma Hinkula, Daniel X. Johansson, Ulf Schröder, Satoshi Uematsu, Björn Rissiek, Claudia Devito, Andreas Bråve, Tina Falkeborn, Sanna Nyström
Published 2013-09-01

Identification of the Mouse T Cell ADP-Ribosylome Uncovers ARTC2.2 Mediated Regulation of CD73 by ADP-Ribosylation

by Mario Leutert, Mario Leutert, Yinghui Duan, Riekje Winzer, Stephan Menzel, Stephan Menzel, Eva Tolosa, Tim Magnus, Michael O. Hottiger, Friedrich Koch-Nolte, Björn Rissiek
Published 2021-08-01

Proteomic Characterization of the Heart and Skeletal Muscle Reveals Widespread Arginine ADP-Ribosylation by the ARTC1 Ectoenzyme

by Mario Leutert, Stephan Menzel, Rickmer Braren, Björn Rissiek, Ann-Katrin Hopp, Kathrin Nowak, Lavinia Bisceglie, Peter Gehrig, Hui Li, Anna Zolkiewska, Friedrich Koch-Nolte, Michael O. Hottiger
Published 2018-08-01

Characterization of brain-derived extracellular vesicles reveals changes in cellular origin after stroke and enrichment of the prion protein with a potential role in cellular uptak...

by Santra Brenna, Hermann C. Altmeppen, Behnam Mohammadi, Björn Rissiek, Florence Schlink, Peter Ludewig, Christoph Krisp, Hartmut Schlüter, Antonio Virgilio Failla, Carola Schneider, Markus Glatzel, Berta Puig, Tim Magnus
Published 2020-01-01

Ecto-ADP-ribosyltransferase ARTC2.1 functionally modulates FcγR1 and FcγR2B on murine microglia

by Björn Rissiek, Stephan Menzel, Mario Leutert, Maike Cordes, Sarah Behr, Larissa Jank, Peter Ludewig, Mathias Gelderblom, Anne Rissiek, Sahil Adriouch, Friedrich Haag, Michael O. Hottiger, Friedrich Koch-Nolte, Tim Magnus
Published 2017-11-01

Generation and Characterization of Specific Monoclonal Antibodies and Nanobodies Directed Against the ATP-Gated Channel P2X4

by Philine Bergmann, Elvira Garcia de Paco, Elvira Garcia de Paco, Björn Rissiek, Stephan Menzel, Gudrun Dubberke, Jennifer Hua, Jennifer Hua, François Rassendren, François Rassendren, Lauriane Ulmann, Lauriane Ulmann, Friedrich Koch-Nolte
Published 2019-11-01

Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody

by Karina Kaczmarek-Hajek, Jiong Zhang, Robin Kopp, Antje Grosche, Björn Rissiek, Anika Saul, Santina Bruzzone, Tobias Engel, Tina Jooss, Anna Krautloher, Stefanie Schuster, Tim Magnus, Christine Stadelmann, Swetlana Sirko, Friedrich Koch-Nolte, Volker Eulenburg, Annette Nicke
Published 2018-08-01

P2X4 receptor controls microglia activation and favors remyelination in autoimmune encephalitis

by Alazne Zabala, Nuria Vazquez‐Villoldo, Björn Rissiek, Jon Gejo, Abraham Martin, Aitor Palomino, Alberto Perez‐Samartín, Krishna R Pulagam, Marco Lukowiak, Estibaliz Capetillo‐Zarate, Jordi Llop, Tim Magnus, Friedrich Koch‐Nolte, Francois Rassendren, Carlos Matute, María Domercq
Published 2018-08-01

CD73-mediated adenosine production by CD8 T cell-derived extracellular vesicles constitutes an intrinsic mechanism of immune suppression

by Enja Schneider, Riekje Winzer, Anne Rissiek, Isabell Ricklefs, Catherine Meyer-Schwesinger, Franz L. Ricklefs, Andreas Bauche, Jochen Behrends, Rudolph Reimer, Santra Brenna, Hauke Wasielewski, Melchior Lauten, Björn Rissiek, Berta Puig, Filippo Cortesi, Tim Magnus, Ralf Fliegert, Christa E. Müller, Nicola Gagliani, Eva Tolosa
Published 2021-10-01