The Mechanism of RNA Interference and the Transposon Silencing in Caenorhabditis elegans

by Marcel Tijsterman, Rena Ketting, Sylvia Fischer, Femke Simmer, Titia Sijen, Kristy Okihara, Bas Tops, Nadine Vastenhouw, Ronald Plasterk
Published 2002-01-01

Quantification and localization of oncogenic receptor tyrosine kinase variant transcripts using molecular inversion probes

by Corina N. A. M. van den Heuvel, Arvid I. Das, Tessa de Bitter, Femke Simmer, Thomas Wurdinger, Miguel Angel Molina-Vila, William P. J. Leenders
Published 2018-05-01

Raf1 Is a DCAF for the Rik1 DDB1-like protein and has separable roles in siRNA generation and chromatin modification.

by Alessia Buscaino, Sharon A White, Douglas R Houston, Erwan Lejeune, Femke Simmer, Flavia de Lima Alves, Piyush T Diyora, Takeshi Urano, Elizabeth H Bayne, Juri Rappsilber, Robin C Allshire
Published 2012-02-01

Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions.

by Femke Simmer, Celine Moorman, Alexander M van der Linden, Ewart Kuijk, Peter V E van den Berghe, Ravi S Kamath, Andrew G Fraser, Julie Ahringer, Ronald H A Plasterk
Published 2003-10-01

Intra-Tumoral Genomic Heterogeneity in Rectal Cancer: Mutational Status Is Dependent on Preoperative Biopsy Depth and Location

by Floris A. Vuijk, Carlijn van de Water, Shannon Lent-van Vliet, Maxime J. M. van der Valk, Femke Simmer, Cornelis J. H. van de Velde, Alexander L. Vahrmeijer, Iris D. Nagtegaal, Denise E. Hilling
Published 2021-05-01

Regulation of DNA Methylation Patterns by CK2-Mediated Phosphorylation of Dnmt3a

by Rachel Deplus, Loïc Blanchon, Arumugam Rajavelu, Abdelhalim Boukaba, Matthieu Defrance, Judith Luciani, Françoise Rothé, Sarah Dedeurwaerder, Hélène Denis, Arie B. Brinkman, Femke Simmer, Fabian Müller, Benjamin Bertin, Maria Berdasco, Pascale Putmans, Emilie Calonne, David W. Litchfield, Yvan de Launoit, Tomasz P. Jurkowski, Hendrik G. Stunnenberg, Christoph Bock, Christos Sotiriou, Mario F. Fraga, Manel Esteller, Albert Jeltsch, François Fuks
Published 2014-08-01

Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

by Arie B. Brinkman, Serena Nik-Zainal, Femke Simmer, F. Germán Rodríguez-González, Marcel Smid, Ludmil B. Alexandrov, Adam Butler, Sancha Martin, Helen Davies, Dominik Glodzik, Xueqing Zou, Manasa Ramakrishna, Johan Staaf, Markus Ringnér, Anieta Sieuwerts, Anthony Ferrari, Sandro Morganella, Thomas Fleischer, Vessela Kristensen, Marta Gut, Marc J. van de Vijver, Anne-Lise Børresen-Dale, Andrea L. Richardson, Gilles Thomas, Ivo G. Gut, John W. M. Martens, John A. Foekens, Michael R. Stratton, Hendrik G. Stunnenberg
Published 2019-04-01