Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression

by Dominik A. Megger, Dominik A. Megger, Jos Philipp, Vu Thuy Khanh Le-Trilling, Barbara Sitek, Mirko Trilling
Published 2017-09-01

A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx

by Christine D. Landsberg, Dominik A. Megger, Dominik A. Megger, Dominik Hotter, Meike U. Rückborn, Mareike Eilbrecht, Jassin Rashidi-Alavijeh, Sebastian Howe, Stefan Heinrichs, Daniel Sauter, Barbara Sitek, Vu Thuy Khanh Le-Trilling, Mirko Trilling
Published 2018-12-01

The PD-1/PD-L1 Pathway Affects the Expansion and Function of Cytotoxic CD8+ T Cells During an Acute Retroviral Infection

by Paul David, Dominik A. Megger, Tamara Kaiser, Tanja Werner, Jia Liu, Jia Liu, Lieping Chen, Barbara Sitek, Ulf Dittmer, Gennadiy Zelinskyy
Published 2019-02-01

Correction to: Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours

by Zeribe C. Nwosu, Nadia Battello, Melanie Rothley, Weronika Piorońska, Barbara Sitek, Matthias P. Ebert, Ute Hofmann, Jonathan Sleeman, Stefan Wölfl, Christoph Meyer, Dominik A. Megger, Steven Dooley
Published 2018-11-01

Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours

by Zeribe C. Nwosu, Nadia Battello, Melanie Rothley, Weronika Piorońska, Barbara Sitek, Matthias P. Ebert, Ute Hofmann, Jonathan Sleeman, Stefan Wölfl, Christoph Meyer, Dominik A. Megger, Steven Dooley
Published 2018-09-01

Acid sphingomyelinase deficiency in Western diet-fed mice protects against adipocyte hypertrophy and diet-induced liver steatosis

by Svenja Sydor, Jan-Peter Sowa, Dominik A. Megger, Martin Schlattjan, Sami Jafoui, Lena Wingerter, Alexander Carpinteiro, Hideo A. Baba, Lars P. Bechmann, Barbara Sitek, Guido Gerken, Erich Gulbins, Ali Canbay
Published 2017-05-01

Combination immunotherapy with anti-PD-L1 antibody and depletion of regulatory T cells during acute viral infections results in improved virus control but lethal immunopathology.

by Paul David, Malgorzata Drabczyk-Pluta, Eva Pastille, Torben Knuschke, Tanja Werner, Nadine Honke, Dominik A Megger, Ilseyar Akhmetzyanova, Namir Shaabani, Annette Eyking-Singer, Elke Cario, Olivia Kershaw, Achim D Gruber, Matthias Tenbusch, Kirsten K Dietze, Mirko Trilling, Jia Liu, Dirk Schadendorf, Hendrik Streeck, Karl S Lang, Youhua Xie, Lisa Zimmer, Barbara Sitek, Annette Paschen, Astrid M Westendorf, Ulf Dittmer, Gennadiy Zelinskyy
Published 2020-03-01