Federalist politics and noble identity in Bohemia during the early constitutional period

by Ute Hofmann
Published 2008-12-01

Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells

by Tamara Heintze, Kathrin Klein, Ute Hofmann, Ulrich M. Zanger
Published 2021-01-01

A Sensitive Sensor Cell Line for the Detection of Oxidative Stress Responses in Cultured Human Keratinocytes

by Ute Hofmann, Melanie Priem, Christine Bartzsch, Thomas Winckler, Karl-Heinz Feller
Published 2014-06-01

Proton pump inhibitors inhibit metformin uptake by organic cation transporters (OCTs).

by Anne T Nies, Ute Hofmann, Claudia Resch, Elke Schaeffeler, Maria Rius, Matthias Schwab
Published 2011-01-01

Interaction of Remdesivir with Clinically Relevant Hepatic Drug Uptake Transporters

by Anne T. Nies, Jörg König, Ute Hofmann, Charlotte Kölz, Martin F. Fromm, Matthias Schwab
Published 2021-03-01

External Model Performance Evaluation of Twelve Infliximab Population Pharmacokinetic Models in Patients with Inflammatory Bowel Disease

by Christina Schräpel, Lukas Kovar, Dominik Selzer, Ute Hofmann, Florian Tran, Walter Reinisch, Matthias Schwab, Thorsten Lehr
Published 2021-08-01

Attenuated lipotoxicity and apoptosis is linked to exogenous and endogenous augmenter of liver regeneration by different pathways.

by Thomas S Weiss, Madeleine Lupke, Sara Ibrahim, Christa Buechler, Julia Lorenz, Petra Ruemmele, Ute Hofmann, Michael Melter, Rania Dayoub
Published 2017-01-01

Gene Suppression of Transketolase-Like Protein 1 (TKTL1) Sensitizes Glioma Cells to Hypoxia and Ionizing Radiation

by Sonja Heller, Gabriele D. Maurer, Christina Wanka, Ute Hofmann, Anna-Luisa Luger, Ines Bruns, Joachim P. Steinbach, Johannes Rieger
Published 2018-07-01

Metabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS

by Sylvia K. Neef, Nicole Janssen, Stefan Winter, Svenja K. Wallisch, Ute Hofmann, Marc H. Dahlke, Matthias Schwab, Thomas E. Mürdter, Mathias Haag
Published 2020-12-01

Oncogenic stress induced by acute hyper-activation of Bcr-Abl leads to cell death upon induction of excessive aerobic glycolysis.

by Michael A Dengler, Annette M Staiger, Matthias Gutekunst, Ute Hofmann, Malgorzata Doszczak, Peter Scheurich, Matthias Schwab, Walter E Aulitzky, Heiko van der Kuip
Published 2011-01-01

Polycyclic Aromatic Hydrocarbons Activate the Aryl Hydrocarbon Receptor and the Constitutive Androstane Receptor to Regulate Xenobiotic Metabolism in Human Liver Cells

by Lisa Goedtke, Heike Sprenger, Ute Hofmann, Felix F. Schmidt, Helen S. Hammer, Ulrich M. Zanger, Oliver Poetz, Albrecht Seidel, Albert Braeuning, Stefanie Hessel-Pras
Published 2021-12-01

Low heritability in pharmacokinetics of talinolol: a pharmacogenetic twin study on the heritability of the pharmacokinetics of talinolol, a putative probe drug of MDR1 and other me...

by Johannes Matthaei, Mladen V. Tzvetkov, Valerie Gal, Cordula Sachse-Seeboth, Daniel Sehrt, Jakob B. Hjelmborg, Ute Hofmann, Matthias Schwab, Reinhold Kerb, Jürgen Brockmöller
Published 2016-11-01

Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage

by Arne Schenk, Ahmed Ghallab, Ute Hofmann, Reham Hassan, Michael Schwarz, Andreas Schuppert, Lars Ole Schwen, Albert Braeuning, Donato Teutonico, Jan G. Hengstler, Lars Kuepfer
Published 2017-07-01

Correction to: Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours

by Zeribe C. Nwosu, Nadia Battello, Melanie Rothley, Weronika Piorońska, Barbara Sitek, Matthias P. Ebert, Ute Hofmann, Jonathan Sleeman, Stefan Wölfl, Christoph Meyer, Dominik A. Megger, Steven Dooley
Published 2018-11-01

Liver cancer cell lines distinctly mimic the metabolic gene expression pattern of the corresponding human tumours

by Zeribe C. Nwosu, Nadia Battello, Melanie Rothley, Weronika Piorońska, Barbara Sitek, Matthias P. Ebert, Ute Hofmann, Jonathan Sleeman, Stefan Wölfl, Christoph Meyer, Dominik A. Megger, Steven Dooley
Published 2018-09-01

Data‐driven personalization of a physiologically based pharmacokinetic model for caffeine: A systematic assessment

by Rebekka Fendt, Ute Hofmann, Annika R. P. Schneider, Elke Schaeffeler, Rolf Burghaus, Ali Yilmaz, Lars Mathias Blank, Reinhold Kerb, Jörg Lippert, Jan‐Frederik Schlender, Matthias Schwab, Lars Kuepfer
Published 2021-07-01

Repurposing Riociguat for Treatment of Refractory Angina Resulting From Coronary Spasm

by Valeria Martínez Pereyra, MS, Andreas Seitz, MD, Astrid Hubert, PhD, Sascha Beck, MS, Ute Hofmann, PhD, Matthias Schwab, MD, Raffi Bekeredjian, MD, Udo Sechtem, MD, Peter Ong, MD
Published 2021-03-01

Central energy metabolism remains robust in acute steatotic hepatocytes challenged by a high free fatty acid load

by Jens Niklas1,*, Anne Bonin1, Stefanie Mangin1, Joachim Bucher1, Stephanie Kopacz2, Madlen Matz-Soja 3, Carlo Thiel3, Rolf Gebhardt3, Ute Hofmann2 & Klaus Mauch1
Published 2012-07-01

Inherited and Acquired Determinants of Hepatic CYP3A Activity in Humans

by Johannes Matthaei, Wagner Hugo Bonat, Reinhold Kerb, Mladen Vassilev Tzvetkov, Jakob Strube, Stefanie Brunke, Cordula Sachse-Seeboth, Daniel Sehrt, Ute Hofmann, Jacob von Bornemann Hjelmborg, Matthias Schwab, Matthias Schwab, Matthias Schwab, Jürgen Brockmöller
Published 2020-08-01

Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression

by Hannah Asperger, Nadia Stamm, Berthold Gierke, Michael Pawlak, Ute Hofmann, Ulrich M. Zanger, Annamaria Marton, Robert L. Katona, Andrea Buhala, Csaba Vizler, Jan-Philipp Cieslik, Eugen Ruckhäberle, Dieter Niederacher, Tanja Fehm, Hans Neubauer, Marina Ludescher
Published 2020-07-01