The Janus-faced Nature of miR-22 in Hematopoiesis: Is It an Oncogenic Tumor Suppressor or Rather a Tumor-Suppressive Oncogene?

by Alexander Arthur Wurm, Daniel G Tenen, Gerhard Behre
Published 2017-01-01

SALL4 and microRNA: The Role of Let-7

by Jun Liu, Madeline A. Sauer, Shaza G. Hussein, Junyu Yang, Daniel G. Tenen, Li Chai
Published 2021-08-01

Styryl Quinazolinones as Potential Inducers of Myeloid Differentiation via Upregulation of C/EBPα

by Radhakrishnan Sridhar, Hisashi Takei, Riyaz Syed, Ikei S. Kobayashi, Liu Bee Hui, Ahmed Kamal, Daniel G. Tenen, Susumu S. Kobayashi
Published 2018-08-01

BIM mediates EGFR tyrosine kinase inhibitor-induced apoptosis in lung cancers with oncogenic EGFR mutations.

by Daniel B Costa, Balázs Halmos, Amit Kumar, Susan T Schumer, Mark S Huberman, Titus J Boggon, Daniel G Tenen, Susumu Kobayashi
Published 2007-10-01

High-speed automatic characterization of rare events in flow cytometric data.

by Yuan Qi, Youhan Fang, David R Sinclair, Shangqin Guo, Meritxell Alberich-Jorda, Jun Lu, Daniel G Tenen, Michael G Kharas, Saumyadipta Pyne
Published 2020-01-01

Cyclic AMP responsive element binding proteins are involved in 'emergency' granulopoiesis through the upregulation of CCAAT/enhancer binding protein β.

by Hideyo Hirai, Naoka Kamio, Gang Huang, Akiko Matsusue, Shinpei Ogino, Nobuhiko Kimura, Sakiko Satake, Eishi Ashihara, Jiro Imanishi, Daniel G Tenen, Taira Maekawa
Published 2013-01-01

Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths

by Samuel L. Wolock, Indira Krishnan, Danielle E. Tenen, Victoria Matkins, Virginia Camacho, Sweta Patel, Puneet Agarwal, Ravi Bhatia, Daniel G. Tenen, Allon M. Klein, Robert S. Welner
Published 2019-07-01

NanoVar: accurate characterization of patients’ genomic structural variants using low-depth nanopore sequencing

by Cheng Yong Tham, Roberto Tirado-Magallanes, Yufen Goh, Melissa J. Fullwood, Bryan T.H. Koh, Wilson Wang, Chin Hin Ng, Wee Joo Chng, Alexandre Thiery, Daniel G. Tenen, Touati Benoukraf
Published 2020-03-01

Monitoring structural modulation of redox-sensitive proteins in cells with MS-CETSA

by Wendi Sun, Lingyun Dai, Han Yu, Brenda Puspita, Tianyun Zhao, Feng Li, Justin L. Tan, Yan Ting Lim, Ming Wei Chen, Radoslaw M. Sobota, Daniel G. Tenen, Nayana Prabhu, Pär Nordlund
Published 2019-06-01

Acetylation of C/EBPα inhibits its granulopoietic function

by Deepak Bararia, Hui Si Kwok, Robert S. Welner, Akihiko Numata, Menyhárt B. Sárosi, Henry Yang, Sheena Wee, Sebastian Tschuri, Debleena Ray, Oliver Weigert, Elena Levantini, Alexander K. Ebralidze, Jayantha Gunaratne, Daniel G. Tenen
Published 2016-03-01

TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter.

by Deepa Rajagopalan, Amit Kumar Pandey, Magdalene Claire Xiuzhen, Kwok Kin Lee, Shainan Hora, Yanzhou Zhang, Boon Haow Chua, Hui Si Kwok, Shreshtha Sailesh Bhatia, Lih Wen Deng, Daniel G Tenen, Dennis Kappei, Sudhakar Jha
Published 2017-10-01

ZNF143 mediates CTCF-bound promoter–enhancer loops required for murine hematopoietic stem and progenitor cell function

by Qiling Zhou, Miao Yu, Roberto Tirado-Magallanes, Bin Li, Lingshi Kong, Mingrui Guo, Zi Hui Tan, Sanghoon Lee, Li Chai, Akihiko Numata, Touati Benoukraf, Melissa Jane Fullwood, Motomi Osato, Bing Ren, Daniel G. Tenen
Published 2021-01-01

Fatty acid synthase mediates EGFR palmitoylation in EGFR mutated non‐small cell lung cancer

by Azhar Ali, Elena Levantini, Jun Ting Teo, Julian Goggi, John G Clohessy, Chan Shuo Wu, Leilei Chen, Henry Yang, Indira Krishnan, Olivier Kocher, Junyan Zhang, Ross A Soo, Kishore Bhakoo, Tan Min Chin, Daniel G Tenen
Published 2018-03-01

Disruption of the C/EBPα—miR-182 balance impairs granulocytic differentiation

by Alexander Arthur Wurm, Polina Zjablovskaja, Miroslava Kardosova, Dennis Gerloff, Daniela Bräuer-Hartmann, Christiane Katzerke, Jens-Uwe Hartmann, Touati Benoukraf, Stephan Fricke, Nadja Hilger, Anne-Marie Müller, Marius Bill, Sebastian Schwind, Daniel G. Tenen, Dietger Niederwieser, Meritxell Alberich-Jorda, Gerhard Behre
Published 2017-06-01

Identification of a Dynamic Core Transcriptional Network in t(8;21) AML that Regulates Differentiation Block and Self-Renewal

by Anetta Ptasinska, Salam A. Assi, Natalia Martinez-Soria, Maria Rosaria Imperato, Jason Piper, Pierre Cauchy, Anna Pickin, Sally R. James, Maarten Hoogenkamp, Dan Williamson, Mengchu Wu, Daniel G. Tenen, Sascha Ott, David R. Westhead, Peter N. Cockerill, Olaf Heidenreich, Constanze Bonifer
Published 2014-09-01

The basic helix-loop-helix transcription factor SHARP1 is an oncogenic driver in MLL-AF6 acute myelogenous leukemia

by Akihiko Numata, Hui Si Kwok, Akira Kawasaki, Jia Li, Qi-Ling Zhou, Jon Kerry, Touati Benoukraf, Deepak Bararia, Feng Li, Erica Ballabio, Marta Tapia, Aniruddha J. Deshpande, Robert S. Welner, Ruud Delwel, Henry Yang, Thomas A. Milne, Reshma Taneja, Daniel G. Tenen
Published 2018-04-01

Scavenging of Labile Heme by Hemopexin Is a Key Checkpoint in Cancer Growth and Metastases

by Giacomo Canesin, Annalisa Di Ruscio, Mailin Li, Simone Ummarino, Andreas Hedblom, Reeham Choudhury, Agnieszka Krzyzanowska, Eva Csizmadia, Macarena Palominos, Anna Stiehm, Alexander Ebralidze, Shao-Yong Chen, Mahmoud A. Bassal, Ping Zhao, Emanuela Tolosano, Laurence Hurley, Anders Bjartell, Daniel G. Tenen, Barbara Wegiel
Published 2020-09-01

Super-Enhancers and Broad H3K4me3 Domains Form Complex Gene Regulatory Circuits Involving Chromatin Interactions

by Fan Cao, Yiwen Fang, Hong Kee Tan, Yufen Goh, Jocelyn Yeen Hui Choy, Bryan Thean Howe Koh, Jiong Hao Tan, Nicolas Bertin, Aroul Ramadass, Ewan Hunter, Jayne Green, Matthew Salter, Alexandre Akoulitchev, Wilson Wang, Wee Joo Chng, Daniel G. Tenen, Melissa J. Fullwood
Published 2017-05-01

Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer

by Giorgia Maroni, Mahmoud A. Bassal, Indira Krishnan, Chee Wai Fhu, Virginia Savova, Rapolas Zilionis, Valerie A. Maymi, Nicole Pandell, Eva Csizmadia, Junyan Zhang, Barbara Storti, Julio Castaño, Riccardo Panella, Jia Li, Corinne E. Gustafson, Sam Fox, Rachel D. Levy, Claire V. Meyerovitz, Peter J. Tramontozzi, Kimberly Vermilya, Assunta De Rienzo, Stefania Crucitta, Daniela S. Bassères, Marla Weetall, Art Branstrom, Alessandra Giorgetti, Raffaele Ciampi, Marzia Del Re, Romano Danesi, Ranieri Bizzarri, Henry Yang, Olivier Kocher, Allon M. Klein, Robert S. Welner, Raphael Bueno, Maria Cristina Magli, John G. Clohessy, Azhar Ali, Daniel G. Tenen, Elena Levantini
Published 2021-04-01