Profiling of 3D Genome Organization in Nasopharyngeal Cancer Needle Biopsy Patient Samples by a Modified Hi-C Approach

by Sambhavi Animesh, Ruchi Choudhary, Ruchi Choudhary, Bertrand Jern Han Wong, Charlotte Tze Jia Koh, Xin Yi Ng, Joshua Kai Xun Tay, Wan-Qin Chong, Han Jian, Leilei Chen, Leilei Chen, Boon Cher Goh, Boon Cher Goh, Boon Cher Goh, Melissa Jane Fullwood, Melissa Jane Fullwood
Published 2021-09-01

H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions

by Yichao Cai, Ying Zhang, Yan Ping Loh, Jia Qi Tng, Mei Chee Lim, Zhendong Cao, Anandhkumar Raju, Erez Lieberman Aiden, Shang Li, Lakshmanan Manikandan, Vinay Tergaonkar, Greg Tucker-Kellogg, Melissa Jane Fullwood
Published 2021-01-01

ZNF143 mediates CTCF-bound promoter–enhancer loops required for murine hematopoietic stem and progenitor cell function

by Qiling Zhou, Miao Yu, Roberto Tirado-Magallanes, Bin Li, Lingshi Kong, Mingrui Guo, Zi Hui Tan, Sanghoon Lee, Li Chai, Akihiko Numata, Touati Benoukraf, Melissa Jane Fullwood, Motomi Osato, Bing Ren, Daniel G. Tenen
Published 2021-01-01

Large-Scale Functional Organization of Long-Range Chromatin Interaction Networks

by Kuljeet Singh Sandhu, Guoliang Li, Huay Mei Poh, Yu Ling Kelly Quek, Yee Yen Sia, Su Qin Peh, Fabianus Hendriyan Mulawadi, Joanne Lim, Mile Sikic, Francesca Menghi, Anbupalam Thalamuthu, Wing Kin Sung, Xiaoan Ruan, Melissa Jane Fullwood, Edison Liu, Peter Csermely, Yijun Ruan
Published 2012-11-01

HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis

by TingDong Yan, Wen Fong Ooi, Aditi Qamra, Alice Cheung, DongLiang Ma, Gopinath Meenakshi Sundaram, Chang Xu, Manjie Xing, LaiFong Poon, Jing Wang, Yan Ping Loh, Jess Hui Jie Ho, Joscelyn Jun Quan Ng, Muhammad Khairul Ramlee, Luay Aswad, Steve G. Rozen, Sujoy Ghosh, Frederic A. Bard, Prabha Sampath, Vinay Tergaonkar, James O. J. Davies, Jim R. Hughes, Eyleen Goh, Xuezhi Bi, Melissa Jane Fullwood, Patrick Tan, Shang Li
Published 2018-01-01

Epigenomic profiling of primary gastric adenocarcinoma reveals super-enhancer heterogeneity

by Wen Fong Ooi, Manjie Xing, Chang Xu, Xiaosai Yao, Muhammad Khairul Ramlee, Mei Chee Lim, Fan Cao, Kevin Lim, Deepak Babu, Lai-Fong Poon, Joyce Lin Suling, Aditi Qamra, Astrid Irwanto, James Qu Zhengzhong, Tannistha Nandi, Ai Ping Lee-Lim, Yang Sun Chan, Su Ting Tay, Ming Hui Lee, James O. J. Davies, Wai Keong Wong, Khee Chee Soo, Weng Hoong Chan, Hock Soo Ong, Pierce Chow, Chow Yin Wong, Sun Young Rha, Jianjun Liu, Axel M. Hillmer, Jim R. Hughes, Steve Rozen, Bin Tean Teh, Melissa Jane Fullwood, Shang Li, Patrick Tan
Published 2016-09-01