Generation of two heterozygous GATA2 CRISPR/Cas9-edited iPSC lines, R398W and R396Q, for modeling GATA2 deficiency

by Julio Castaño, Damia Romero-Moya, Yvonne Richaud-Patin, Alessandra Giorgetti
Published 2021-08-01

Generation, genome edition and characterization of iPSC lines from a patient with coenzyme Q10 deficiency harboring a heterozygous mutation in COQ4 gene

by Damià Romero-Moya, Julio Castaño, Carlos Santos-Ocaña, Plácido Navas, Pablo Menendez
Published 2017-10-01

Generation of two transgene-free human iPSC lines from CD133+ cord blood cells

by Estibaliz Arellano-Viera, Lorea Zabaleta, Julio Castaño, Garikoitz Azkona, Xonia Carvajal-Vergara, Alessandra Giorgetti
Published 2019-04-01

SETD7 Regulates the Differentiation of Human Embryonic Stem Cells.

by Julio Castaño, Cristina Morera, Borja Sesé, Stephanie Boue, Carles Bonet-Costa, Merce Martí, Alicia Roque, Albert Jordan, Maria J Barrero
Published 2016-01-01

Efficient Recreation of t(11;22) EWSR1-FLI1+ in Human Stem Cells Using CRISPR/Cas9

by Raul Torres-Ruiz, Marta Martinez-Lage, Maria C. Martin, Aida Garcia, Clara Bueno, Julio Castaño, Juan C. Ramirez, Pablo Menendez, Juan C. Cigudosa, Sandra Rodriguez-Perales
Published 2017-05-01

Generation and characterization of a human iPSC cell line expressing inducible Cas9 in the “safe harbor” AAVS1 locus

by Julio Castaño, Clara Bueno, Senda Jiménez-Delgado, Heleia Roca-Ho, Mario F. Fraga, Agustín F. Fernandez, Mahito Nakanishi, Raúl Torres-Ruiz, Sandra Rodríguez-Perales, Pablo Menéndez
Published 2017-05-01

Robustness of Catalytically Dead Cas9 Activators in Human Pluripotent and Mesenchymal Stem Cells

by Paolo Petazzi, Raul Torres-Ruiz, Antonella Fidanza, Heleia Roca-Ho, Francisco Gutierrez-Agüera, Julio Castaño, Sandra Rodriguez-Perales, Rafael Díaz de la Guardia, Belén López-Millán, Anna Bigas, Lesley M. Forrester, Clara Bueno, Pablo Menéndez
Published 2020-06-01

Fast and Efficient Neural Conversion of Human Hematopoietic Cells

by Julio Castaño, Pablo Menendez, Cristina Bruzos-Cidon, Marco Straccia, Amaia Sousa, Lorea Zabaleta, Nerea Vazquez, Amaia Zubiarrain, Kai-Christian Sonntag, Luisa Ugedo, Xonia Carvajal-Vergara, Josep Maria Canals, Maria Torrecilla, Rosario Sanchez-Pernaute, Alessandra Giorgetti
Published 2014-12-01

Detailed Characterization of Mesenchymal Stem/Stromal Cells from a Large Cohort of AML Patients Demonstrates a Definitive Link to Treatment Outcomes

by Rafael Diaz de la Guardia, Belen Lopez-Millan, Jessie R. Lavoie, Clara Bueno, Julio Castaño, Maite Gómez-Casares, Susana Vives, Laura Palomo, Manel Juan, Julio Delgado, Maria L. Blanco, Josep Nomdedeu, Alberto Chaparro, Jose Luis Fuster, Eduardo Anguita, Michael Rosu-Myles, Pablo Menéndez
Published 2017-06-01

GATA2 Promotes Hematopoietic Development and Represses Cardiac Differentiation of Human Mesoderm

by Julio Castaño, Sergi Aranda, Clara Bueno, Fernando J. Calero-Nieto, Eva Mejia-Ramirez, Jose Luis Mosquera, Enrique Blanco, Xiaonan Wang, Cristina Prieto, Lorea Zabaleta, Elisabetta Mereu, Meritxell Rovira, Senda Jiménez-Delgado, Daniel R. Matson, Holger Heyn, Emery H. Bresnick, Berthold Göttgens, Luciano Di Croce, Pablo Menendez, Angel Raya, Alessandra Giorgetti
Published 2019-09-01

Development of a Novel Anti-CD19 Chimeric Antigen Receptor: A Paradigm for an Affordable CAR T Cell Production at Academic Institutions

by Maria Castella, Anna Boronat, Raquel Martín-Ibáñez, Vanina Rodríguez, Guillermo Suñé, Miguel Caballero, Berta Marzal, Lorena Pérez-Amill, Beatriz Martín-Antonio, Julio Castaño, Clara Bueno, Olga Balagué, Europa Azucena González-Navarro, Carles Serra-Pages, Pablo Engel, Ramon Vilella, Daniel Benitez-Ribas, Valentín Ortiz-Maldonado, Joan Cid, Jaime Tabera, Josep M. Canals, Miquel Lozano, Tycho Baumann, Anna Vilarrodona, Esteve Trias, Elías Campo, Pablo Menendez, Álvaro Urbano-Ispizua, Jordi Yagüe, Patricia Pérez-Galán, Susana Rives, Julio Delgado, Manel Juan
Published 2019-03-01

Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer

by Giorgia Maroni, Mahmoud A. Bassal, Indira Krishnan, Chee Wai Fhu, Virginia Savova, Rapolas Zilionis, Valerie A. Maymi, Nicole Pandell, Eva Csizmadia, Junyan Zhang, Barbara Storti, Julio Castaño, Riccardo Panella, Jia Li, Corinne E. Gustafson, Sam Fox, Rachel D. Levy, Claire V. Meyerovitz, Peter J. Tramontozzi, Kimberly Vermilya, Assunta De Rienzo, Stefania Crucitta, Daniela S. Bassères, Marla Weetall, Art Branstrom, Alessandra Giorgetti, Raffaele Ciampi, Marzia Del Re, Romano Danesi, Ranieri Bizzarri, Henry Yang, Olivier Kocher, Allon M. Klein, Robert S. Welner, Raphael Bueno, Maria Cristina Magli, John G. Clohessy, Azhar Ali, Daniel G. Tenen, Elena Levantini
Published 2021-04-01