Preconditioning with endoplasmic reticulum stress ameliorates endothelial cell inflammation.

by Antony Leonard, Adrienne W Paton, Monaliza El-Quadi, James C Paton, Fabeha Fazal
Published 2014-01-01

Chaperone-Mediated Sec61 Channel Gating during ER Import of Small Precursor Proteins Overcomes Sec61 Inhibitor-Reinforced Energy Barrier

by Sarah Haßdenteufel, Nicholas Johnson, Adrienne W. Paton, James C. Paton, Stephen High, Richard Zimmermann
Published 2018-05-01

The signal sequence influences post-translational ER translocation at distinct stages.

by Nicholas Johnson, Sarah Haßdenteufel, Melanie Theis, Adrienne W Paton, James C Paton, Richard Zimmermann, Stephen High
Published 2013-01-01

The signal peptide plus a cluster of positive charges in prion protein dictate chaperone-mediated Sec61 channel gating

by Anke Ziska, Jörg Tatzelt, Johanna Dudek, Adrienne W. Paton, James C. Paton, Richard Zimmermann, Sarah Haßdenteufel
Published 2019-03-01

Comparative Characterization of Shiga Toxin Type 2 and Subtilase Cytotoxin Effects on Human Renal Epithelial and Endothelial Cells Grown in Monolayer and Bilayer Conditions.

by Romina S Álvarez, Flavia Sacerdoti, Carolina Jancic, Adrienne W Paton, James C Paton, Cristina Ibarra, María M Amaral
Published 2016-01-01

The impact of pneumolysin on the macrophage response to Streptococcus pneumoniae is strain-dependent.

by Richard M Harvey, Catherine E Hughes, Adrienne W Paton, Claudia Trappetti, Rodney K Tweten, James C Paton
Published 2014-01-01

Effects of Escherichia coli subtilase cytotoxin and Shiga toxin 2 on primary cultures of human renal tubular epithelial cells.

by Laura B Márquez, Natalia Velázquez, Horacio A Repetto, Adrienne W Paton, James C Paton, Cristina Ibarra, Claudia Silberstein
Published 2014-01-01

Action of shiga toxin type-2 and subtilase cytotoxin on human microvascular endothelial cells.

by María M Amaral, Flavia Sacerdoti, Carolina Jancic, Horacio A Repetto, Adrienne W Paton, James C Paton, Cristina Ibarra
Published 2013-01-01

Crosstalk between Human Microvascular Endothelial Cells and Tubular Epithelial Cells Modulates Pro-Inflammatory Responses Induced by Shiga Toxin Type 2 and Subtilase Cytotoxin

by Romina S. Álvarez, Carolina Jancic, Nicolás Garimano, Flavia Sacerdoti, Adrienne W. Paton, James C. Paton, Cristina Ibarra, María M. Amaral
Published 2019-11-01

Combined Action of Shiga Toxin Type 2 and Subtilase Cytotoxin in the Pathogenesis of Hemolytic Uremic Syndrome

by Romina S. Álvarez, Fernando D. Gómez, Elsa Zotta, Adrienne W. Paton, James C. Paton, Cristina Ibarra, Flavia Sacerdoti, María M. Amaral
Published 2021-07-01

Ouabain Protects Human Renal Cells against the Cytotoxic Effects of Shiga Toxin Type 2 and Subtilase Cytotoxin

by María M. Amaral, Magalí C. Girard, Romina S. Álvarez, Adrienne W. Paton, James C. Paton, Horacio A. Repetto, Flavia Sacerdoti, Cristina A. Ibarra
Published 2017-07-01

Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation

by William K. Taverner, Egon J. Jacobus, John Christianson, Brian Champion, Adrienne W. Paton, James C. Paton, Weiheng Su, Ryan Cawood, Len W. Seymour, Janet Lei-Rossmann
Published 2019-12-01

Chaperone-Targeting Cytotoxin and Endoplasmic Reticulum Stress-Inducing Drug Synergize to Kill Cancer Cells

by Joseph M. Backer, Arcadius V. Krivoshein, Carl V. Hamby, John Pizzonia, Kenneth S. Gilbert, Yonaton S. Ray, Harrison Brand, Adrienne W. Paton, James C. Paton, Marina V. Backer
Published 2009-11-01

Autoinducer 2 Signaling via the Phosphotransferase FruA Drives Galactose Utilization by Streptococcus pneumoniae, Resulting in Hypervirulence

by Claudia Trappetti, Lauren J. McAllister, Austen Chen, Hui Wang, Adrienne W. Paton, Marco R. Oggioni, Christopher A. McDevitt, James C. Paton, Larry S. McDaniel
Published 2017-01-01

Structure aided design of a Neu5Gc specific lectin

by Christopher J. Day, Adrienne W. Paton, Melanie A. Higgins, Lucy K. Shewell, Freda E.-C. Jen, Benjamin L. Schulz, Brock P. Herdman, James C. Paton, Michael P. Jennings
Published 2017-05-01

Interaction mapping of endoplasmic reticulum ubiquitin ligases identifies modulators of innate immune signalling

by Emma J Fenech, Federica Lari, Philip D Charles, Roman Fischer, Marie Laétitia-Thézénas, Katrin Bagola, Adrienne W Paton, James C Paton, Mads Gyrd-Hansen, Benedikt M Kessler, John C Christianson
Published 2020-07-01

Shiga Toxin–producing Escherichia coli Strains Negative for Locus of Enterocyte Effacement

by Hayley J. Newton, Joan Sloan, Dieter M. Bulach, Torsten Seemann, Cody C. Allison, Marija Tauschek, Roy M. Robins-Browne, James C. Paton, Thomas S. Whittam, Adrienne W. Paton, Elizabeth L. Hartland
Published 2009-03-01

The Pneumococcal Alpha-Glycerophosphate Oxidase Enhances Nasopharyngeal Colonization through Binding to Host Glycoconjugates

by Layla K. Mahdi, Melanie A. Higgins, Christopher J. Day, Joe Tiralongo, Lauren E. Hartley-Tassell, Michael P. Jennings, David L. Gordon, Adrienne W. Paton, James C. Paton, Abiodun D. Ogunniyi
Published 2017-04-01

Proinsulin misfolding is an early event in the progression to type 2 diabetes

by Anoop Arunagiri, Leena Haataja, Anita Pottekat, Fawnnie Pamenan, Soohyun Kim, Lori M Zeltser, Adrienne W Paton, James C Paton, Billy Tsai, Pamela Itkin-Ansari, Randal J Kaufman, Ming Liu, Peter Arvan
Published 2019-06-01

Calnexin Depletion by Endoplasmic Reticulum Stress During Cholestasis Inhibits the Na+‐Taurocholate Cotransporting Polypeptide

by Marion J.D. Robin, Monique D. Appelman, Harmjan R. Vos, Robert M. van Es, James C. Paton, Adrienne W. Paton, Boudewijn Burgering, Peter Fickert, Jarom Heijmans, Stan F.J. van de Graaf
Published 2018-12-01