Insulin Biosynthetic Interaction Network Component, TMEM24, Facilitates Insulin Reserve Pool Release

by Anita Pottekat, Scott Becker, Kathryn R. Spencer, John R. Yates, III, Gerard Manning, Pamela Itkin-Ansari, William E. Balch
Published 2013-09-01

Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment

by Brad L. Jakubison, Patrick G. Schweickert, Sarah E. Moser, Yi Yang, Hongyu Gao, Kathleen Scully, Pamela Itkin‐Ansari, Yunlong Liu, Stephen F. Konieczny
Published 2018-06-01

E47 Governs the MYC-CDKN1B/p27KIP1-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16INK4A and Wild-Type p53Summary

by Kathleen M. Scully, Reyhaneh Lahmy, Lia Signaevskaia, Roman Sasik, Rachel Medal, Heejung Kim, Randall French, Brian James, Yifan Wu, Andrew M. Lowy, Pamela Itkin-Ansari
Published 2018-01-01

PDIA1/P4HB is required for efficient proinsulin maturation and ß cell health in response to diet induced obesity

by Insook Jang, Anita Pottekat, Juthakorn Poothong, Jing Yong, Jacqueline Lagunas-Acosta, Adriana Charbono, Zhouji Chen, Donalyn L Scheuner, Ming Liu, Pamela Itkin-Ansari, Peter Arvan, Randal J Kaufman
Published 2019-06-01

Proinsulin misfolding is an early event in the progression to type 2 diabetes

by Anoop Arunagiri, Leena Haataja, Anita Pottekat, Fawnnie Pamenan, Soohyun Kim, Lori M Zeltser, Adrienne W Paton, James C Paton, Billy Tsai, Pamela Itkin-Ansari, Randal J Kaufman, Ming Liu, Peter Arvan
Published 2019-06-01

The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells.

by Justin R Hassler, Donalyn L Scheuner, Shiyu Wang, Jaeseok Han, Vamsi K Kodali, Philip Li, Julie Nguyen, Jenny S George, Cory Davis, Shengyang P Wu, Yongsheng Bai, Maureen Sartor, James Cavalcoli, Harmeet Malhi, Gregory Baudouin, Yaoyang Zhang, John R Yates, Pamela Itkin-Ansari, Niels Volkmann, Randal J Kaufman
Published 2015-10-01