A regulatory role for NBS1 in strand-specific mutagenesis during somatic hypermutation.

by Likun Du, Deborah K Dunn-Walters, Krystyna H Chrzanowska, Tanja Stankovic, Ashwin Kotnis, Xin Li, Jiayi Lu, Gösta Eggertsen, Claire Brittain, Sergey W Popov, Andrew R Gennery, A Malcolm R Taylor, Qiang Pan-Hammarström
Published 2008-06-01

Investigating a role for E2A in the regulation of gene conversion and somatic hypermutation

by Conlon, T. M.
Published 2006

Directed evolution of human single-chain variable fragments (scFv) by somatic hypermutation

by Lim, Wai Yen Alfred
Published 2014

The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.

by Devin Sok, Uri Laserson, Jonathan Laserson, Yi Liu, Francois Vigneault, Jean-Philippe Julien, Bryan Briney, Alejandra Ramos, Karen F Saye, Khoa Le, Alison Mahan, Shenshen Wang, Mehran Kardar, Gur Yaari, Laura M Walker, Birgitte B Simen, Elizabeth P St John, Po-Ying Chan-Hui, Kristine Swiderek, Steven H Kleinstein, Galit Alter, Michael S Seaman, Arup K Chakraborty, Daphne Koller, Ian A Wilson, George M Church, Dennis R Burton, Pascal Poignard
Published 2013-01-01

Evaluation of Somatic Hypermutation Status in Chronic Lymphocytic Leukemia (CLL) in the Era of Next Generation Sequencing

by Sanjeev Kumar Gupta, David S. Viswanatha, Keyur P. Patel
Published 2020-05-01

T Cell Receptor Alpha Chain Genes in the Teleost Ballan Wrasse (Labrus bergylta) Are Subjected to Somatic Hypermutation

by Sumaira Bilal, Kai Kristoffer Lie, Øystein Sæle, Ivar Hordvik
Published 2018-05-01

Correction: The Effects of Somatic Hypermutation on Neutralization and Binding in the PGT121 Family of Broadly Neutralizing HIV Antibodies.

by Devin Sok, Uri Laserson, Jonathan Laserson, Yi Liu, Francois Vigneault, Jean-Philippe Julien, Bryan Briney, Alejandra Ramos, Karen F. Saye, Khoa Le, Alison Mahan, Shenshen Wang, Mehran Kardar, Gur Yaari, Laura M. Walker, Birgitte B. Simen, Elizabeth P. St. John, Po-Ying Chan-Hui, Kristine Swiderek, Stephen H. Kleinstein, Galit Alter, Michael S. Seaman, Arup K. Chakraborty, Daphne Koller, Ian A. Wilson, George M. Church, Dennis R. Burton, Pascal Poignard
Published 2013-12-01

Repertoire Sequencing of B Cells Elucidates the Role of UNG and Mismatch Repair Proteins in Somatic Hypermutation in Humans

by Hanna IJspeert, Hanna IJspeert, Pauline A. van Schouwenburg, Ingrid Pico-Knijnenburg, Jan Loeffen, Laurence Brugieres, Gertjan J. Driessen, Claudia Blattmann, Manon Suerink, Danuta Januszkiewicz-Lewandowska, Amedeo A. Azizi, Marcus G. Seidel, Heinz Jacobs, Mirjam van der Burg
Published 2019-08-01

Human Immunodeficiency Virus Tat Protein Aids V Region Somatic Hypermutation in Human B Cells

by Xiaohua Wang, Zhi Duan, Guojun Yu, Manxia Fan, Matthew D. Scharff, Anne Moscona
Published 2018-04-01

Somatic hypermutation analysis for improved identification of B cell clonal families from next-generation sequencing data.

by Nima Nouri, Steven H Kleinstein
Published 2020-06-01

Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput Immunoglobulin sequencing data.

by Gur eYaari, Gur eYaari, Jason eVander Heiden, Mohamed eUduman, Daniel eGadala-Maria, Namita eGupta, Joel N.H. Stern, Joel N.H. Stern, Kevin eO'Connor, David eHafler, Uri eLaserson, Francois eVigneault, Steven eKleinstein
Published 2013-11-01

Gene-Specific Substitution Profiles Describe the Types and Frequencies of Amino Acid Changes during Antibody Somatic Hypermutation

by Zizhang Sheng, Zizhang Sheng, Chaim A. Schramm, Chaim A. Schramm, Chaim A. Schramm, Rui Kong, NISC Comparative Sequencing Program, James C. Mullikin, John R. Mascola, Peter D. Kwong, Peter D. Kwong, Lawrence Shapiro, Lawrence Shapiro, Lawrence Shapiro
Published 2017-05-01

Correlations in Somatic Hypermutation Between Sites in IGHV Genes Can Be Explained by Interactions Between AID and/or Polη Hotspots

by Artem Krantsevich, Catherine Tang, Thomas MacCarthy, Thomas MacCarthy
Published 2021-02-01

Immunoglobulin somatic hypermutation has clinical impact in DLBCL and potential implications...

by Zijun Y. Xu-Monette, Jianyong Li, Yi Xia, Beryl Crossley, Robert D. Bremel, Yi Miao, Min Xiao, Thomas Snyder, Ganiraju C. Manyam, Xiaohong Tan, Hongwei Zhang, Carlo Visco, Alexandar Tzankov, Karen Dybkaer, Govind Bhagat, Wayne Tam, Hua You, Eric D. Hsi, J. Han van Krieken, Jooryung Huh, Maurilio Ponzoni, Andrés J. M. Ferreri, Michael B. Møller, Miguel A. Piris, Jane N. Winter, Jeffrey T. Medeiros, Bing Xu, Yong Li, Ilan Kirsch, Ken H. Young
Published 2019-10-01

Antibody lineages with evidence of somatic hypermutation persisting for >4 years in a South African subject with broad neutralizing activity

by Moody M, Trama AM, Bonsignori M, Tsao C, Drinker MS, Gurley TC, Amos JD, Eudailey JA, Armand LC, Parks R, Lloyd KE, Wang S, Seo K, Lee J, Jackson KJ, Hoh R, Pham T, Roskin KM, Boyd SD, Fire AZ, Gray ES, Morris L, Liao H, Tomaras GD, Kepler TB, Kelsoe G, Haynes BF
Published 2012-09-01

High affinity humanized antibodies without making hybridomas; immunization paired with mammalian cell display and in vitro somatic hypermutation.

by Audrey D McConnell, Minjee Do, Tamlyn Y Neben, Vladimir Spasojevic, Josh MacLaren, Andy P Chen, Laurence Altobell, John L Macomber, Ashley D Berkebile, Robert A Horlick, Peter M Bowers, David J King
Published 2012-01-01

Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes

by Kunkel Thomas A, Frahm Christin, Adkison Linda R, Rogozin Igor B, Mayorov Vladimir I, Pavlov Youri I
Published 2005-06-01

P20-20 LB. Indels in V4 share sequence features with insertions and deletions during somatic hypermutation of immunoglobulins

by Graziosi C, Pantaleo G, Guglietta S
Published 2009-10-01