A Population Dynamics Model for Clonal Diversity in a Germinal Center

by Assaf Amitai, Assaf Amitai, Assaf Amitai, Luka Mesin, Gabriel D. Victora, Mehran Kardar, Arup K. Chakraborty, Arup K. Chakraborty, Arup K. Chakraborty, Arup K. Chakraborty
Published 2017-09-01

Signaling cascades modulate the speed of signal propagation through space.

by Christopher C Govern, Arup K Chakraborty
Published 2009-01-01

Regulation of signal duration and the statistical dynamics of kinase activation by scaffold proteins.

by Jason W Locasale, Arup K Chakraborty
Published 2008-06-01

Stochastic responses may allow genetically diverse cell populations to optimize performance with simpler signaling networks.

by Christopher C Govern, Arup K Chakraborty
Published 2013-01-01

The low spike density of HIV may have evolved because of the effects of T helper cell depletion on affinity maturation.

by Assaf Amitai, Arup K Chakraborty, Mehran Kardar
Published 2018-08-01

Correction: Protein Clusters on the T Cell Surface May Suppress Spurious Early Signaling Events

by Woo Chung, Steven M. Abel, Arup K. Chakraborty
Published 2012-01-01

Protein clusters on the T cell surface may suppress spurious early signaling events.

by Woo Chung, Steven M Abel, Arup K Chakraborty
Published 2012-01-01

Correction: Protein Clusters on the T Cell Surface May Suppress Spurious Early Signaling Events.

by Woo Chung, Steven M. Abel, Arup K. Chakraborty
Published 2012-01-01

A model for genetic and epigenetic regulatory networks identifies rare pathways for transcription factor induced pluripotency.

by Maxim N Artyomov, Alexander Meissner, Arup K Chakraborty
Published 2010-05-01

A model for how signal duration can determine distinct outcomes of gene transcription programs.

by Kevin D Fowler, Vijay K Kuchroo, Arup K Chakraborty
Published 2012-01-01

Theory, models and biology

by Wenying Shou, Carl T Bergstrom, Arup K Chakraborty, Frances K Skinner
Published 2015-07-01

Correction: Directed Migration of Positively Selected Thymocytes Visualized in Real Time.

by Colleen M Witt, Subhadip Raychaudhuri, Brian Schaefer, Arup K Chakraborty, Ellen A Robey
Published 2005-10-01

Deconvolving mutational patterns of poliovirus outbreaks reveals its intrinsic fitness landscape

by Ahmed A. Quadeer, John P. Barton, Arup K. Chakraborty, Matthew R. McKay
Published 2020-01-01

Role of framework mutations and antibody flexibility in the evolution of broadly neutralizing antibodies

by Victor Ovchinnikov, Joy E Louveau, John P Barton, Martin Karplus, Arup K Chakraborty
Published 2018-02-01

Directed migration of positively selected thymocytes visualized in real time.

by Colleen M Witt, Subhadip Raychaudhuri, Brian Schaefer, Arup K Chakraborty, Ellen A Robey
Published 2005-06-01

Affinity Inequality among Serum Antibodies That Originate in Lymphoid Germinal Centers.

by Myungsun Kang, Timothy J Eisen, Ellen A Eisen, Arup K Chakraborty, Herman N Eisen
Published 2015-01-01

Computational prediction of broadly neutralizing HIV-1 antibody epitopes from neutralization activity data.

by Andrew L Ferguson, Emilia Falkowska, Laura M Walker, Michael S Seaman, Dennis R Burton, Arup K Chakraborty
Published 2013-01-01

Relative rate and location of intra-host HIV evolution to evade cellular immunity are predictable

by John P. Barton, Nilu Goonetilleke, Thomas C. Butler, Bruce D. Walker, Andrew J. McMichael, Arup K. Chakraborty
Published 2016-05-01

Predominance of positive epistasis among drug resistance-associated mutations in HIV-1 protease.

by Tian-Hao Zhang, Lei Dai, John P Barton, Yushen Du, Yuxiang Tan, Wenwen Pang, Arup K Chakraborty, James O Lloyd-Smith, Ren Sun
Published 2020-10-01

Deconstruction of the Ras switching cycle through saturation mutagenesis

by Pradeep Bandaru, Neel H Shah, Moitrayee Bhattacharyya, John P Barton, Yasushi Kondo, Joshua C Cofsky, Christine L Gee, Arup K Chakraborty, Tanja Kortemme, Rama Ranganathan, John Kuriyan
Published 2017-07-01