Hypoxia-induced preadipocyte factor 1 expression in human lung fibroblasts through ERK/PEA3/c-Jun pathway

by Wun-Hao Cheng, Chia-Ling Chen, Jing-Yun Chen, Chien-Huang Lin, Bing-Chang Chen
Published 2021-07-01

CircMTO1 inhibits ox-LDL-stimulated vascular smooth muscle cell proliferation and migration via regulating the miR-182-5p/RASA1 axis

by Ningning Ji, Yu Wang, Xinyan Gong, Shimao Ni, Hui Zhang
Published 2021-07-01

The long noncoding RNA MEG3 regulates Ras-MAPK pathway through RASA1 in trophoblast and is associated with unexplained recurrent spontaneous abortion

by Jun Zhang, Xinqiong Liu, Yali Gao
Published 2021-07-01

ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy

by Lihong Lu, Ziwen Zhong, Jiahui Gu, Ke Nan, Minmin Zhu, Changhong Miao
Published 2021-07-01

MSCs‑derived exosomes attenuate ischemia-reperfusion brain injury and inhibit microglia apoptosis might via exosomal miR-26a-5p mediated suppression of CDK6

by Chang Cheng, Xiuying Chen, Yuhan Wang, Wenchao Cheng, Xuzheng Zuo, Weiju Tang, Wen Huang
Published 2021-07-01

Therapeutic administration of etoposide coincides with reduced systemic HMGB1 levels in macrophage activation syndrome

by Karin Palmblad, Hanna Schierbeck, Erik Sundberg, Anna-Carin Horne, Helena Erlandsson Harris, Jan-Inge Henter, Ulf Andersson
Published 2021-05-01

CircPTK2-miR-181c-5p-HMGB1: a new regulatory pathway for microglia activation and hippocampal neuronal apoptosis induced by sepsis

by Min Li, Junwen Hu, Yucong Peng, Jingbo Li, Reng Ren
Published 2021-05-01

The cytotoxic conjugate of highly internalizing tetravalent antibody for targeting FGFR1-overproducing cancer cells

by Marta Poźniak, Natalia Porębska, Mateusz Adam Krzyścik, Aleksandra Sokołowska-Wędzina, Kamil Jastrzębski, Martyna Sochacka, Jakub Szymczyk, Małgorzata Zakrzewska, Jacek Otlewski, Łukasz Opaliński
Published 2021-05-01

Phosphorylation of islet-1 serine 269 by CDK1 increases its transcriptional activity and promotes cell proliferation in gastric cancer

by Qiong Shi, Xiaomei Ni, Ming Lei, Quansong Xia, Yan Dong, Qiao Zhang, Weiping Wang
Published 2021-05-01

Digital imaging-assisted quantification of H3K27me3 immunoexpression in luminal A/B-like, HER2-negative, invasive breast cancer predicts patient survival and risk of recurrence

by Mário Fontes-Sousa, João Lobo, Silvana Lobo, Sofia Salta, Maria Amorim, Paula Lopes, Luís Antunes, Susana Palma de Sousa, Rui Henrique, Carmen Jerónimo
Published 2020-02-01

Discovery of vanoxerine dihydrochloride as a CDK2/4/6 triple-inhibitor for the treatment of human hepatocellular carcinoma

by Ying Zhu, Kun-Bin Ke, Zhong-Kun Xia, Hong-Jian Li, Rong Su, Chao Dong, Feng-Mei Zhou, Lin Wang, Rong Chen, Shi-Guo Wu, Hui Zhao, Peng Gu, Kwong-Sak Leung, Man-Hon Wong, Gang Lu, Jian-Ying Zhang, Bing-Hua Jiang, Jian-Ge Qiu, Xi-Nan Shi, Marie Chia-mi Lin
Published 2021-02-01

ELAVL1 is transcriptionally activated by FOXC1 and promotes ferroptosis in myocardial ischemia/reperfusion injury by regulating autophagy

by Hui-Yong Chen, Ze-Zhou Xiao, Xiao Ling, Rong-Ning Xu, Peng Zhu, Shao-Yi Zheng
Published 2021-02-01

The role of RICTOR amplification in targeted therapy and drug resistance

by Deze Zhao, Man Jiang, Xiaochun Zhang, Helei Hou
Published 2020-02-01

Elevated MST1 leads to apoptosis via depletion of YAP1 in cardiomyocytes exposed to high glucose

by Dongmei Su, Yanhua Li, Lina Guan, Qian Li, Cuige Shi, Xu Ma, Yonghui Song
Published 2021-02-01

D-allose alleviates ischemia/reperfusion (I/R) injury in skin flap via MKP-1

by Jihui Ju, Ruixing Hou, Ping Zhang
Published 2020-02-01

Diagnostic and prognostic impact of cytokeratin 18 expression in human tumors: a tissue microarray study on 11,952 tumors

by Anne Menz, Timo Weitbrecht, Natalia Gorbokon, Franziska Büscheck, Andreas M. Luebke, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Doris Höflmayer, Sören Weidemann, Christoph Fraune, Katharina Möller, Christian Bernreuther, Patrick Lebok, Till Clauditz, Guido Sauter, Ria Uhlig, Waldemar Wilczak, Stefan Steurer, Sarah Minner, Eike Burandt, Rainer Krech, David Dum, Till Krech, Andreas Marx, Ronald Simon
Published 2021-02-01

Cardioprotective effects of genetically engineered cardiac stem cells by spheroid formation on ischemic cardiomyocytes

by Han Saem Jeong, Chi-Yeon Park, Jong-Ho Kim, Hyung Joon Joo, Seung-Cheol Choi, Ji-Hyun Choi, I-Rang Lim, Jae Hyoung Park, Soon Jun Hong, Do-Sun Lim
Published 2020-01-01

LINC00242/miR-1-3p/G6PD axis regulates Warburg effect and affects gastric cancer proliferation and apoptosis

by Peng Deng, Kai Li, Feng Gu, Tao Zhang, Wenyan Zhao, Ming Sun, Bin Hou
Published 2021-01-01

Expression of Concern to: Diet restriction inhibits apoptosis and HMGB1 oxidation and promotes inflammatory cell recruitment during acetaminophen hepatoxicity

by Daniel James Antoine, Dominic P. Williams, Anja Kipar, Hugh Laverty, B. Kevin Park
Published 2020-01-01

Inhibition of mitochondrial carrier homolog 2 (MTCH2) suppresses tumor invasion and enhances sensitivity to temozolomide in malignant glioma

by Qiuyun Yuan, Wanchun Yang, Shuxin Zhang, Tengfei Li, Mingrong Zuo, Xingwang Zhou, Junhong Li, Mao Li, Xiaoqiang Xia, Mina Chen, Yanhui Liu
Published 2021-01-01