High Affinity Promotes Internalization of Engineered Antibodies Targeting FGFR1

by Łukasz Opaliński, Jakub Szymczyk, Martyna Szczepara, Marika Kucińska, Daniel Krowarsch, Małgorzata Zakrzewska, Jacek Otlewski
Published 2018-05-01

FHF1 is a bona fide fibroblast growth factor that activates cellular signaling in FGFR-dependent manner

by Martyna Sochacka, Lukasz Opalinski, Jakub Szymczyk, Marta B. Zimoch, Aleksandra Czyrek, Daniel Krowarsch, Jacek Otlewski, Malgorzata Zakrzewska
Published 2020-05-01

The cytotoxic conjugate of highly internalizing tetravalent antibody for targeting FGFR1-overproducing cancer cells

by Marta Poźniak, Natalia Porębska, Mateusz Adam Krzyścik, Aleksandra Sokołowska-Wędzina, Kamil Jastrzębski, Martyna Sochacka, Jakub Szymczyk, Małgorzata Zakrzewska, Jacek Otlewski, Łukasz Opaliński
Published 2021-05-01

FGFR1 clustering with engineered tetravalent antibody improves the efficiency and modifies the mechanism of receptor internalization

by Marta Pozniak, Aleksandra Sokolowska‐Wedzina, Kamil Jastrzebski, Jakub Szymczyk, Natalia Porebska, Mateusz Adam Krzyscik, Malgorzata Zakrzewska, Marta Miaczynska, Jacek Otlewski, Lukasz Opalinski
Published 2020-09-01