Mechanistic Characterization of RASGRP1 Variants Identifies an hnRNP-K-Regulated Transcriptional Enhancer Contributing to SLE Susceptibility

by Julio E. Molineros, Bhupinder Singh, Chikashi Terao, Chikashi Terao, Yukinori Okada, Jakub Kaplan, Barbara McDaniel, Shuji Akizuki, Celi Sun, Carol F. Webb, Loren L. Looger, Swapan K. Nath
Published 2019-05-01

Regulation of Cellular Heterogeneity and Rates of Symmetric and Asymmetric Divisions in Triple-Negative Breast Cancer

by Roy Z. Granit, Hadas Masury, Reba Condiotti, Yaakov Fixler, Yael Gabai, Tzofia Glikman, Simona Dalin, Eitan Winter, Yuval Nevo, Einat Carmon, Tamar Sella, Amir Sonnenblick, Tamar Peretz, Ulrich Lehmann, Keren Paz, Federica Piccioni, Aviv Regev, David E. Root, Ittai Ben-Porath
Published 2018-09-01

Nephronectin is Correlated with Poor Prognosis in Breast Cancer and Promotes Metastasis via its Integrin-Binding Motifs

by Tonje S. Steigedal, Jimita Toraskar, Richard P. Redvers, Marit Valla, Synnøve N. Magnussen, Anna M. Bofin, Signe Opdahl, Steinar Lundgren, Bedrich L. Eckhardt, John M. Lamar, Judy Doherty, Richard O. Hynes, Robin L. Anderson, Gunbjørg Svineng
Published 2018-04-01

Absence of Carbohydrate Response Element Binding Protein in Adipocytes Causes Systemic Insulin Resistance and Impairs Glucose Transport

by Archana Vijayakumar, Pratik Aryal, Jennifer Wen, Ismail Syed, Reema P. Vazirani, Pedro M. Moraes-Vieira, Joao Paulo Camporez, Molly R. Gallop, Rachel J. Perry, Odile D. Peroni, Gerald I. Shulman, Alan Saghatelian, Timothy E. McGraw, Barbara B. Kahn
Published 2017-10-01

Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons

by Matthew E. Klein, Thomas J. Younts, Carmen Freire Cobo, Adina R. Buxbaum, Jonathan Aow, Hediye Erdjument-Bromage, Stéphane Richard, Roberto Malinow, Thomas A. Neubert, Robert H. Singer, Pablo E. Castillo, Bryen A. Jordan
Published 2019-11-01

The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance

by Manya Warrier, Diana M. Shih, Amy C. Burrows, Daniel Ferguson, Anthony D. Gromovsky, Amanda L. Brown, Stephanie Marshall, Allison McDaniel, Rebecca C. Schugar, Zeneng Wang, Jessica Sacks, Xin Rong, Thomas de Aguiar Vallim, Jeff Chou, Pavlina T. Ivanova, David S. Myers, H. Alex Brown, Richard G. Lee, Rosanne M. Crooke, Mark J. Graham, Xiuli Liu, Paolo Parini, Peter Tontonoz, Aldon J. Lusis, Stanley L. Hazen, Ryan E. Temel, J. Mark Brown
Published 2015-01-01

Sequencing three crocodilian genomes to illuminate the evolution of archosaurs and amniotes

by St John, John, Braun, Edward, Isberg, Sally, Miles, Lee, Chong, Amanda, Gongora, Jaime, Dalzell, Pauline, Moran, Christopher, Bed'Hom, Bertrand, Abzhanov, Arkhat, Burgess, Shane, Cooksey, Amanda, Castoe, Todd, Crawford, Nicholas, Densmore, Llewellyn, Drew, Jennifer, Edwards, Scott, Faircloth, Brant, Fujita, Matthew, Greenwold, Matthew, Hoffmann, Federico, Howard, Jonathan, Iguchi, Taisen, Janes, Daniel, Khan, Shahid, Kohno, Satomi, de Koning, AP Jason, Lance, Stacey, McCarthy, Fiona, McCormack, John
Published 2012

DRscDB: A single-cell RNA-seq resource for data mining and data comparison across species

by Yanhui Hu, Sudhir Gopal Tattikota, Yifang Liu, Aram Comjean, Yue Gao, Corey Forman, Grace Kim, Jonathan Rodiger, Irene Papatheodorou, Gilberto dos Santos, Stephanie E. Mohr, Norbert Perrimon
Published 2021-01-01

CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance[S]

by J. Mark Brown, Jenna L. Betters, Caleb Lord, Yinyan Ma, Xianlin Han, Kui Yang, Heather M. Alger, John Melchior, Janet Sawyer, Ramesh Shah, Martha D. Wilson, Xiuli Liu, Mark J. Graham, Richard Lee, Rosanne Crooke, Gerald I. Shulman, Bingzhong Xue, Hang Shi, Liqing Yu
Published 2010-11-01

The CALeDNA program: Citizen scientists and researchers inventory California's biodiversity

by Rachel S. Meyer, Miroslava Munguia Ramos, Meixi Lin, Teia M. Schweizer, Zachary Gold, Dannise Ruiz Ramos, Sabrina Shirazi, Gaurav Kandlikar, Wai-Yin Kwan, Emily E. Curd, Amanda Freise, Jordan Moberg Parker, Jason P. Sexton, Regina Wetzer, N. Dean Pentcheff, Adam R. Wall, Lenore Pipes, Ana Garcia-Vedrenne, Maura Palacios Mejia, Tiara Moore, Chloe Orland, Kimberly M. Ballare, Anna Worth, Eric Beraut, Emma L. Aronson, Rasmus Nielsen, Harris A. Lewin, Paul H. Barber, Jeff Wall, Nathan Kraft, Beth Shapiro, Robert K. Wayne
Published 2021-03-01

Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis

by Dmitry Rychkov, Dmitry Rychkov, Dmitry Rychkov, Jessica Neely, Tomiko Oskotsky, Steven Yu, Steven Yu, Noah Perlmutter, Joanne Nititham, Alexander Carvidi, Melissa Krueger, Andrew Gross, Lindsey A. Criswell, Lindsey A. Criswell, Lindsey A. Criswell, Lindsey A. Criswell, Judith F. Ashouri, Marina Sirota, Marina Sirota
Published 2021-06-01

β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression

by Ioanna Mavrommati, Roberta Faedda, Giovanni Galasso, Jie Li, Kamila Burdova, Roman Fischer, Benedikt M. Kessler, Zunamys I. Carrero, Daniele Guardavaccaro, Michele Pagano, Vincenzo D’Angiolella
Published 2018-09-01

Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons

by Disi An, Ryosuke Fujiki, Dylan E Iannitelli, John W Smerdon, Shuvadeep Maity, Matthew F Rose, Alon Gelber, Elizabeth K Wanaselja, Ilona Yagudayeva, Joun Y Lee, Christine Vogel, Hynek Wichterle, Elizabeth C Engle, Esteban Orlando Mazzoni
Published 2019-06-01

High performance communication by people with paralysis using an intracortical brain-computer interface

by Chethan Pandarinath, Paul Nuyujukian, Christine H Blabe, Brittany L Sorice, Jad Saab, Francis R Willett, Leigh R Hochberg, Krishna V Shenoy, Jaimie M Henderson
Published 2017-02-01

TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau

by Maxime WC Rousseaux, Maria de Haro, Cristian A Lasagna-Reeves, Antonia De Maio, Jeehye Park, Paymaan Jafar-Nejad, Ismael Al-Ramahi, Ajay Sharma, Lauren See, Nan Lu, Luis Vilanova-Velez, Tiemo J Klisch, Thomas F Westbrook, Juan C Troncoso, Juan Botas, Huda Y Zoghbi
Published 2016-10-01

NUDT21-spanning CNVs lead to neuropsychiatric disease and altered MeCP2 abundance via alternative polyadenylation

by Vincenzo A Gennarino, Callison E Alcott, Chun-An Chen, Arindam Chaudhury, Madelyn A Gillentine, Jill A Rosenfeld, Sumit Parikh, James W Wheless, Elizabeth R Roeder, Dafne DG Horovitz, Erin K Roney, Janice L Smith, Sau W Cheung, Wei Li, Joel R Neilson, Christian P Schaaf, Huda Y Zoghbi
Published 2015-08-01

Rasgrp1 mutation increases naïve T-cell CD44 expression and drives mTOR-dependent accumulation of Helios+ T cells and autoantibodies

by Stephen R Daley, Kristen M Coakley, Daniel Y Hu, Katrina L Randall, Craig N Jenne, Andre Limnander, Darienne R Myers, Noelle K Polakos, Anselm Enders, Carla Roots, Bhavani Balakishnan, Lisa A Miosge, Geoff Sjollema, Edward M Bertram, Matthew A Field, Yunli Shao, T Daniel Andrews, Belinda Whittle, S Whitney Barnes, John R Walker, Jason G Cyster, Christopher C Goodnow, Jeroen P Roose
Published 2013-12-01

Regulation of SCFTIR1/AFBs E3 ligase assembly by S-nitrosylation of Arabidopsis SKP1-like1 impacts on auxin signaling

by María José Iglesias, María Cecilia Terrile, Natalia Correa-Aragunde, Silvana Lorena Colman, Alicia Izquierdo-Álvarez, Diego Fernando Fiol, Ramiro París, Nuria Sánchez-López, Anabel Marina, Luz Irina A. Calderón Villalobos, Mark Estelle, Lorenzo Lamattina, Antonio Martínez-Ruiz, Claudia Anahí Casalongué
Published 2018-09-01

Distinct Requirements of CHD4 during B Cell Development and Antibody Response

by Wei-Feng Yen, Rahul Sharma, Montserrat Cols, Colleen M. Lau, Ashutosh Chaudhry, Priyanka Chowdhury, William T. Yewdell, Bharat Vaidyanathan, Amy Sun, Maryaline Coffre, Joseph N. Pucella, Chun-Chin Chen, Maria Jasin, Joseph C. Sun, Alexander Y. Rudensky, Sergei B. Koralov, Jayanta Chaudhuri
Published 2019-04-01