A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids

by Diana M. Shih, Heidi R. Kast-Woelbern, Jack Wong, Yu-Rong Xia, Peter A. Edwards, Aldons J. Lusis
Published 2006-02-01

Paraoxonase-1 Inhibits Oxidized Low-Density Lipoprotein-Induced Metabolic Alterations and Apoptosis in Endothelial Cells: A Nondirected Metabolomic Study

by Anabel García-Heredia, Judit Marsillach, Anna Rull, Iris Triguero, Isabel Fort, Bharti Mackness, Michael Mackness, Diana M. Shih, Jorge Joven, Jordi Camps
Published 2013-01-01

PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity

by Diana M. Shih, Yonghong Meng, Tamer Sallam, Laurent Vergnes, Michelle L. Shu, Karen Reue, Peter Tontonoz, Alan M. Fogelman, Aldons J. Lusis, Srinivasa T. Reddy
Published 2019-01-01

Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice

by Christina Charles-Schoeman, Jennifer Wang, Ani Shahbazian, Yuen Yin Lee, Xiaoyan Wang, Victor Grijalva, Ernest Brahn, Diana M. Shih, Asokan Devarajan, Christy Montano, Aldons J. Lusis, Srinivasa T. Reddy
Published 2020-10-01

NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice

by Fangfei Guo, Marcus Seldin, Miklós Péterfy, Sarada Charugundla, Zhiqiang Zhou, Stephen D. Lee, Alice Mouton, Prashant Rajbhandari, Wenchao Zhang, Matteo Pellegrini, Peter Tontonoz, Aldons J. Lusis, Diana M. Shih
Published 2021-08-01

Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis[S]

by Diana M. Shih, Zeneng Wang, Richard Lee, Yonghong Meng, Nam Che, Sarada Charugundla, Hannah Qi, Judy Wu, Calvin Pan, J. Mark Brown, Thomas Vallim, Brian J. Bennett, Mark Graham, Stanley L. Hazen, Aldons J. Lusis
Published 2015-01-01

Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice

by Wenchao Zhang, Aika Miikeda, Jonathan Zuckerman, Xun Jia, Sarada Charugundla, Zhiqiang Zhou, Karolina Elżbieta Kaczor-Urbanowicz, Clara Magyar, Fangfei Guo, Zeneng Wang, Matteo Pellegrini, Stanley L. Hazen, Susanne B. Nicholas, Aldons J. Lusis, Diana M. Shih
Published 2021-01-01

The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance

by Manya Warrier, Diana M. Shih, Amy C. Burrows, Daniel Ferguson, Anthony D. Gromovsky, Amanda L. Brown, Stephanie Marshall, Allison McDaniel, Rebecca C. Schugar, Zeneng Wang, Jessica Sacks, Xin Rong, Thomas de Aguiar Vallim, Jeff Chou, Pavlina T. Ivanova, David S. Myers, H. Alex Brown, Richard G. Lee, Rosanne M. Crooke, Mark J. Graham, Xiuli Liu, Paolo Parini, Peter Tontonoz, Aldon J. Lusis, Stanley L. Hazen, Ryan E. Temel, J. Mark Brown
Published 2015-01-01

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue

by Rebecca C. Schugar, Diana M. Shih, Manya Warrier, Robert N. Helsley, Amy Burrows, Daniel Ferguson, Amanda L. Brown, Anthony D. Gromovsky, Markus Heine, Arunachal Chatterjee, Lin Li, Xinmin S. Li, Zeneng Wang, Belinda Willard, YongHong Meng, Hanjun Kim, Nam Che, Calvin Pan, Richard G. Lee, Rosanne M. Crooke, Mark J. Graham, Richard E. Morton, Carl D. Langefeld, Swapan K. Das, Lawrence L. Rudel, Nizar Zein, Arthur J. McCullough, Srinivasan Dasarathy, W.H. Wilson Tang, Bernadette O. Erokwu, Chris A. Flask, Markku Laakso, Mete Civelek, Sathyamangla V. Naga Prasad, Joerg Heeren, Aldons J. Lusis, Stanley L. Hazen, J. Mark Brown
Published 2017-06-01

The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue

by Rebecca C. Schugar, Diana M. Shih, Manya Warrier, Robert N. Helsley, Amy Burrows, Daniel Ferguson, Amanda L. Brown, Anthony D. Gromovsky, Markus Heine, Arunachal Chatterjee, Lin Li, Xinmin S. Li, Zeneng Wang, Belinda Willard, YongHong Meng, Hanjun Kim, Nam Che, Calvin Pan, Richard G. Lee, Rosanne M. Crooke, Mark J. Graham, Richard E. Morton, Carl D. Langefeld, Swapan K. Das, Lawrence L. Rudel, Nizar Zein, Arthur J. McCullough, Srinivasan Dasarathy, W.H. Wilson Tang, Bernadette O. Erokwu, Chris A. Flask, Markku Laakso, Mete Civelek, Sathyamangla V. Naga Prasad, Joerg Heeren, Aldons J. Lusis, Stanley L. Hazen, J. Mark Brown
Published 2017-07-01