Datasets from an interaction proteomics screen for substrates of the SCFβTrCP ubiquitin ligase

by Roberto Magliozzi, Mao Peng, Shabaz Mohammed, Daniele Guardavaccaro, Albert J.R. Heck, Teck Yew Low
Published 2015-09-01

Phosphatidic acid-dependent localization and basal de-phosphorylation of RA-GEFs regulate lymphocyte trafficking

by Sayaka Ishihara, Tsuyoshi Sato, Guangwei Du, Daniele Guardavaccaro, Akihiko Nakajima, Satoshi Sawai, Tohru Kataoka, Koko Katagiri
Published 2020-06-01

Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells

by Angela Lauriola, Andrea Martello, Sebastian Fantini, Gaetano Marverti, Tommaso Zanocco-Marani, Pierpaola Davalli, Daniele Guardavaccaro, Sabine Mai, Andrea Caporali, Domenico D’Arca
Published 2020-04-01

Essential role for the d-Asb11 cul5 Box domain for proper notch signaling and neural cell fate decisions in vivo.

by Maria A Sartori da Silva, Jin-Ming Tee, Judith Paridaen, Anke Brouwers, Vincent Runtuwene, Danica Zivkovic, Sander H Diks, Daniele Guardavaccaro, Maikel P Peppelenbosch
Published 2010-11-01

β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression

by Ioanna Mavrommati, Roberta Faedda, Giovanni Galasso, Jie Li, Kamila Burdova, Roman Fischer, Benedikt M. Kessler, Zunamys I. Carrero, Daniele Guardavaccaro, Michele Pagano, Vincenzo D’Angiolella
Published 2018-09-01

Inheritance of the Golgi Apparatus and Cytokinesis Are Controlled by Degradation of GBF1

by Roberto Magliozzi, Zunamys I. Carrero, Teck Yew Low, Laurensia Yuniati, Christian Valdes-Quezada, Flore Kruiswijk, Koen van Wijk, Albert J.R. Heck, Catherine L. Jackson, Daniele Guardavaccaro
Published 2018-06-01

Ubiquitylation of the ER-Shaping Protein Lunapark via the CRL3KLHL12 Ubiquitin Ligase Complex

by Laurensia Yuniati, Angela Lauriola, Manouk Gerritsen, Susana Abreu, Eric Ni, Chiara Tesoriero, Jacob O. Onireti, Teck Yew Low, Albert J.R. Heck, Andrea Vettori, Timothy Cardozo, Daniele Guardavaccaro
Published 2020-05-01

Human papillomavirus (HPV) upregulates the cellular deubiquitinase UCHL1 to suppress the keratinocyte's innate immune response.

by Rezaul Karim, Bart Tummers, Craig Meyers, Jennifer L Biryukov, Samina Alam, Claude Backendorf, Veena Jha, Rienk Offringa, Gert-Jan B van Ommen, Cornelis J M Melief, Daniele Guardavaccaro, Judith M Boer, Sjoerd H van der Burg
Published 2013-01-01

Itch/β-arrestin2-dependent non-proteolytic ubiquitylation of SuFu controls Hedgehog signalling and medulloblastoma tumorigenesis

by Paola Infante, Roberta Faedda, Flavia Bernardi, Francesca Bufalieri, Ludovica Lospinoso Severini, Romina Alfonsi, Daniela Mazzà, Mariangela Siler, Sonia Coni, Agnese Po, Marialaura Petroni, Elisabetta Ferretti, Mattia Mori, Enrico De Smaele, Gianluca Canettieri, Carlo Capalbo, Marella Maroder, Isabella Screpanti, Marcel Kool, Stefan M. Pfister, Daniele Guardavaccaro, Alberto Gulino, Lucia Di Marcotullio
Published 2018-03-01

ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP

by Francesca Bufalieri, Paola Infante, Flavia Bernardi, Miriam Caimano, Paolo Romania, Marta Moretti, Ludovica Lospinoso Severini, Julie Talbot, Ombretta Melaiu, Mirella Tanori, Laura Di Magno, Diana Bellavia, Carlo Capalbo, Stéphanie Puget, Enrico De Smaele, Gianluca Canettieri, Daniele Guardavaccaro, Luca Busino, Angelo Peschiaroli, Simonetta Pazzaglia, Giuseppe Giannini, Gerry Melino, Franco Locatelli, Alberto Gulino, Olivier Ayrault, Doriana Fruci, Lucia Di Marcotullio
Published 2019-07-01