Identification of the virulence landscape essential for Entamoeba histolytica invasion of the human colon.

Entamoeba histolytica is the pathogenic amoeba responsible for amoebiasis, an infectious disease targeting human tissues. Amoebiasis arises when virulent trophozoites start to destroy the muco-epithelial barrier by first crossing the mucus, then killing host cells, triggering inflammation and subseq...

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Bibliographic Details
Main Authors: Roman Thibeaux, Christian Weber, Chung-Chau Hon, Marie-Agnès Dillies, Patrick Avé, Jean-Yves Coppée, Elisabeth Labruyère, Nancy Guillén
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3868522?pdf=render