The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site.

The PLIN4 variant rs8887 modulates obesity related phenotypes in humans through creation of a novel miR-522 seed site.

PLIN4 is a member of the PAT family of lipid storage droplet (LSD) proteins. Associations between seven single nucleotide polymorphisms (SNPs) at human PLIN4 with obesity related phenotypes were investigated using meta-analysis followed by a determination if these phenotypes are modulated by interac...

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Main Authors: Kris Richardson, Qiong Louie-Gao, Donna K Arnett, Laurence D Parnell, Chao-Qiang Lai, Alberto Davalos, Caroline S Fox, Serkalem Demissie, L Adrienne Cupples, Carlos Fernandez-Hernando, Jose M Ordovas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3080366?pdf=render

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http://europepmc.org/articles/PMC3080366?pdf=render

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