Black Raspberries Suppress Colorectal Cancer by Enhancing Smad4 Expression in Colonic Epithelium and Natural Killer Cells

Black Raspberries Suppress Colorectal Cancer by Enhancing Smad4 Expression in Colonic Epithelium and Natural Killer Cells

Innate immune cells in the tumor microenvironment have been proposed to control the transition from benign to malignant stages. In many cancers, increased infiltration of natural killer (NK) cells associates with good prognosis. Although the mechanisms that enable NK cells to restrain colorectal can...

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Bibliographic Details
Main Authors: Yi-Wen Huang, Chien-Wei Lin, Pan Pan, Tianjiao Shan, Carla Elena Echeveste, Yue Yang Mo, Hsin-Tzu Wang, Mohammed Aldakkak, Susan Tsai, Kiyoko Oshima, Martha Yearsley, Jianbo Xiao, Hui Cao, Chongde Sun, Ming Du, Weibin Bai, Jianhua Yu, Li-Shu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Immunology
Subjects:
black raspberries
Smad4
natural killer cells
colorectal (colon) cancer
human clinical trials
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.570683/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.570683/full

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