DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.

DNA methylation in the human cerebral cortex is dynamically regulated throughout the life span and involves differentiated neurons.

The role of DNA cytosine methylation, an epigenetic regulator of chromatin structure and function, during normal and pathological brain development and aging remains unclear. Here, we examined by MethyLight PCR the DNA methylation status at 50 loci, encompassing primarily 5' CpG islands of gene...

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Bibliographic Details
Main Authors: Kimberly D Siegmund, Caroline M Connor, Mihaela Campan, Tiffany I Long, Daniel J Weisenberger, Detlev Biniszkiewicz, Rudolf Jaenisch, Peter W Laird, Schahram Akbarian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1964879?pdf=render

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http://europepmc.org/articles/PMC1964879?pdf=render

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