Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease.

Sequential inflammatory processes define human progression from M. tuberculosis infection to tuberculosis disease.

Our understanding of mechanisms underlying progression from Mycobacterium tuberculosis infection to pulmonary tuberculosis disease in humans remains limited. To define such mechanisms, we followed M. tuberculosis-infected adolescents longitudinally. Blood samples from forty-four adolescents who ulti...

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Bibliographic Details
Main Authors: Thomas J Scriba, Adam Penn-Nicholson, Smitha Shankar, Tom Hraha, Ethan G Thompson, David Sterling, Elisa Nemes, Fatoumatta Darboe, Sara Suliman, Lynn M Amon, Hassan Mahomed, Mzwandile Erasmus, Wendy Whatney, John L Johnson, W Henry Boom, Mark Hatherill, Joe Valvo, Mary Ann De Groote, Urs A Ochsner, Alan Aderem, Willem A Hanekom, Daniel E Zak, other members of the ACS cohort study team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5689825?pdf=render

Internet

http://europepmc.org/articles/PMC5689825?pdf=render

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