Mouse newborn cells allow highly productive mouse cytomegalovirus replication, constituting a novel convenient primary cell culture system.

by Vu Thuy Khanh Le-Trilling, Mirko Trilling
Published 2017-01-01

Mouse Cytomegalovirus M34 Encodes a Non-essential, Nuclear, Early-Late Expressed Protein Required for Efficient Viral Replication

by Mareike Eilbrecht, Vu Thuy Khanh Le-Trilling, Mirko Trilling
Published 2020-05-01

Cellular Cullin RING Ubiquitin Ligases: Druggable Host Dependency Factors of Cytomegaloviruses

by Tanja Becker, Vu Thuy Khanh Le-Trilling, Mirko Trilling
Published 2019-04-01

Nedd8-Activating Enzyme Is a Druggable Host Dependency Factor of Human and Mouse Cytomegalovirus

by Yulia Alejandra Flores-Martínez, Vu Thuy Khanh Le-Trilling, Mirko Trilling
Published 2021-08-01

Deciphering of the Human Interferon-Regulated Proteome by Mass Spectrometry-Based Quantitative Analysis Reveals Extent and Dynamics of Protein Induction and Repression

by Dominik A. Megger, Dominik A. Megger, Jos Philipp, Vu Thuy Khanh Le-Trilling, Barbara Sitek, Mirko Trilling
Published 2017-09-01

The human cytomegalovirus protein UL147A downregulates the most prevalent MICA allele: MICA*008, to evade NK cell-mediated killing.

by Einat Seidel, Liat Dassa, Corinna Schuler, Esther Oiknine-Djian, Dana G Wolf, Vu Thuy Khanh Le-Trilling, Ofer Mandelboim
Published 2021-05-01

The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity

by Vu Thuy Khanh Le-Trilling, Tanja Becker, Aharon Nachshon, Noam Stern-Ginossar, Lara Schöler, Sebastian Voigt, Hartmut Hengel, Mirko Trilling
Published 2020-02-01

HCMV vCXCL1 Binds Several Chemokine Receptors and Preferentially Attracts Neutrophils over NK Cells by Interacting with CXCR2

by Rachel Yamin, Laura S.M. Lecker, Yiska Weisblum, Alon Vitenshtein, Vu Thuy Khanh Le-Trilling, Dana G. Wolf, Ofer Mandelboim
Published 2016-05-01

Human Cytomegalovirus-Induced Degradation of CYTIP Modulates Dendritic Cell Adhesion and Migration

by Christiane S. Heilingloh, Linda Grosche, Christina Draßner, Petra Mühl-Zürbes, Lisa Kamm, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Alexander Steinkasserer
Published 2017-04-01

Human cytomegalovirus antagonizes activation of Fcγ receptors by distinct and synergizing modes of IgG manipulation

by Philipp Kolb, Katja Hoffmann, Annika Sievert, Henrike Reinhard, Eva Merce-Maldonado, Vu Thuy Khanh Le-Trilling, Anne Halenius, Dominique Gütle, Hartmut Hengel
Published 2021-03-01

The Transcription and Translation Landscapes during Human Cytomegalovirus Infection Reveal Novel Host-Pathogen Interactions.

by Osnat Tirosh, Yifat Cohen, Alina Shitrit, Odem Shani, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Gilgi Friedlander, Marvin Tanenbaum, Noam Stern-Ginossar
Published 2015-01-01

Immunization with a murine cytomegalovirus based vector encoding retrovirus envelope confers strong protection from Friend retrovirus challenge infection.

by Nadine Bongard, Vu Thuy Khanh Le-Trilling, Anna Malyshkina, Meike Rückborn, Kerstin Wohlgemuth, Ina Wensing, Sonja Windmann, Ulf Dittmer, Mirko Trilling, Wibke Bayer
Published 2019-09-01

A Novel In-Cell ELISA Assay Allows Rapid and Automated Quantification of SARS-CoV-2 to Analyze Neutralizing Antibodies and Antiviral Compounds

by Lara Schöler, Vu Thuy Khanh Le-Trilling, Mareike Eilbrecht, Denise Mennerich, Olympia E. Anastasiou, Adalbert Krawczyk, Adalbert Krawczyk, Anke Herrmann, Ulf Dittmer, Mirko Trilling
Published 2020-10-01

HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11.

by Cosima Zimmermann, Daniel Kowalewski, Liane Bauersfeld, Andreas Hildenbrand, Carolin Gerke, Magdalena Schwarzmüller, Vu Thuy Khanh Le-Trilling, Stefan Stevanovic, Hartmut Hengel, Frank Momburg, Anne Halenius
Published 2019-09-01

Opposing Development of Cytotoxic and Follicular Helper CD4 T Cells Controlled by the TCF-1-Bcl6 Nexus

by Tiziano Donnarumma, George R. Young, Julia Merkenschlager, Urszula Eksmond, Nadine Bongard, Stephen L. Nutt, Claude Boyer, Ulf Dittmer, Vu Thuy Khanh Le-Trilling, Mirko Trilling, Wibke Bayer, George Kassiotis
Published 2016-11-01

The Donor Major Histocompatibility Complex Class I Chain-Related Molecule A Allele rs2596538 G Predicts Cytomegalovirus Viremia in Kidney Transplant Recipients

by Hana Rohn, Rafael Tomoya Michita, Esther Schwich, Sebastian Dolff, Anja Gäckler, Mirko Trilling, Vu Thuy Khanh Le-Trilling, Benjamin Wilde, Johannes Korth, Falko M. Heinemann, Peter A. Horn, Andreas Kribben, Oliver Witzke, Vera Rebmann
Published 2018-05-01

A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx

by Christine D. Landsberg, Dominik A. Megger, Dominik A. Megger, Dominik Hotter, Meike U. Rückborn, Mareike Eilbrecht, Jassin Rashidi-Alavijeh, Sebastian Howe, Stefan Heinrichs, Daniel Sauter, Barbara Sitek, Vu Thuy Khanh Le-Trilling, Mirko Trilling
Published 2018-12-01

Occurrence of COVID-19 Symptoms During SARS-CoV-2 Infection Defines Waning of Humoral Immunity

by Jun Wu, Jun Wu, Bo-Yun Liang, Bo-Yun Liang, Yao-Hui Fang, Hua Wang, Hua Wang, Xiao-Li Yang, Xiao-Li Yang, Shu Shen, Liang-Kai Chen, Su-Meng Li, Su-Meng Li, Si-Hong Lu, Si-Hong Lu, Tian-Dan Xiang, Tian-Dan Xiang, Jia Liu, Jia Liu, Vu Thuy Khanh Le-Trilling, Vu Thuy Khanh Le-Trilling, Meng-Ji Lu, Meng-Ji Lu, Dong-Liang Yang, Dong-Liang Yang, Fei Deng, Ulf Dittmer, Ulf Dittmer, Mirko Trilling, Mirko Trilling, Xin Zheng, Xin Zheng
Published 2021-08-01