Human Cytomegalovirus and Autoimmune Disease

by Anne Halenius, Hartmut Hengel
Published 2014-01-01

Elusive Role of the CD94/NKG2C NK Cell Receptor in the Response to Cytomegalovirus: Novel Experimental Observations in a Reporter Cell System

by Aldi Pupuleku, Marcel Costa-García, Domènec Farré, Hartmut Hengel, Hartmut Hengel, Ana Angulo, Ana Angulo, Aura Muntasell, Miguel López-Botet, Miguel López-Botet
Published 2017-10-01

Exploitation of herpesviral transactivation allows quantitative reporter gene-based assessment of virus entry and neutralization.

by Henrike Reinhard, Vu Thuy Khanh Le, Mats Ohlin, Hartmut Hengel, Mirko Trilling
Published 2011-01-01

Absence of cross-presenting cells in the salivary gland and viral immune evasion confine cytomegalovirus immune control to effector CD4 T cells.

by Senta M Walton, Sanja Mandaric, Nicole Torti, Albert Zimmermann, Hartmut Hengel, Annette Oxenius
Published 2011-08-01

Identification of DNA-damage DNA-binding protein 1 as a conditional essential factor for cytomegalovirus replication in interferon-γ-stimulated cells.

by Mirko Trilling, Vu Thuy Khanh Le, Manuela Fiedler, Albert Zimmermann, Elke Bleifuss, Hartmut Hengel
Published 2011-06-01

Antibody Cross-Reactivity between Porcine Cytomegalovirus (PCMV) and Human Herpesvirus-6 (HHV-6)

by Uwe Fiebig, Angela Holzer, Daniel Ivanusic, Elena Plotzki, Hartmut Hengel, Frank Neipel, Joachim Denner
Published 2017-10-01

A Novel, Broad-Acting Peptide Inhibitor of Double-Stranded DNA Virus Gene Expression and Replication

by Zsolt Ruzsics, Zsolt Ruzsics, Zsolt Ruzsics, Katja Hoffmann, Katja Hoffmann, André Riedl, André Riedl, Adalbert Krawczyk, Adalbert Krawczyk, Marek Widera, Marek Widera, Helene Sertznig, Leonie Schipper, Valeria Kapper-Falcone, Valeria Kapper-Falcone, Valeria Kapper-Falcone, Monika Debreczeny, Wolfgang Ernst, Reingard Grabherr, Hartmut Hengel, Hartmut Hengel, Hartmut Hengel, Hanna Harant
Published 2020-11-01

Varicella-zoster virus seroprevalence in children and adolescents in the pre-varicella vaccine era, Germany

by Miriam Wiese-Posselt, Anette Siedler, Annette Mankertz, Andreas Sauerbrei, Hartmut Hengel, Ole Wichmann, Christina Poethko-Müller
Published 2017-05-01

Anti-inflammatory consequences of bile acid accumulation in virus-infected bile duct ligated mice.

by Stephanie Rattay, Dirk Graf, Andreas Kislat, Bernhard Homey, Diran Herebian, Dieter Häussinger, Hartmut Hengel, Albert Zimmermann, Anna-Kathrin Schupp
Published 2018-01-01

A highly conserved sequence of the viral TAP inhibitor ICP47 is required for freezing of the peptide transport cycle

by Tony Matschulla, Richard Berry, Carolin Gerke, Marius Döring, Julia Busch, Jennifer Paijo, Ulrich Kalinke, Frank Momburg, Hartmut Hengel, Anne Halenius
Published 2017-06-01

The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity

by Vu Thuy Khanh Le-Trilling, Tanja Becker, Aharon Nachshon, Noam Stern-Ginossar, Lara Schöler, Sebastian Voigt, Hartmut Hengel, Mirko Trilling
Published 2020-02-01

Human cytomegalovirus antagonizes activation of Fcγ receptors by distinct and synergizing modes of IgG manipulation

by Philipp Kolb, Katja Hoffmann, Annika Sievert, Henrike Reinhard, Eva Merce-Maldonado, Vu Thuy Khanh Le-Trilling, Anne Halenius, Dominique Gütle, Hartmut Hengel
Published 2021-03-01

Influence of demographic changes on the impact of vaccination against varicella and herpes zoster in Germany – a mathematical modelling study

by Johannes Horn, Oliver Damm, Wolfgang Greiner, Hartmut Hengel, Mirjam E. Kretzschmar, Anette Siedler, Bernhard Ultsch, Felix Weidemann, Ole Wichmann, André Karch, Rafael T. Mikolajczyk
Published 2018-01-01

Cytomegalovirus restricts ICOSL expression on antigen-presenting cells disabling T cell co-stimulation and contributing to immune evasion

by Guillem Angulo, Jelena Zeleznjak, Pablo Martínez-Vicente, Joan Puñet-Ortiz, Hartmut Hengel, Martin Messerle, Annette Oxenius, Stipan Jonjic, Astrid Krmpotić, Pablo Engel, Ana Angulo
Published 2021-01-01

COVID-19 in a Severely Immunosuppressed Patient With Life-Threatening Eosinophilic Granulomatosis With Polyangiitis

by Markus A. Schramm, Nils Venhoff, Dirk Wagner, Jens Thiel, Daniela Huzly, Nils Craig-Mueller, Marcus Panning, Hartmut Hengel, Winfried V. Kern, Reinhard E. Voll
Published 2020-08-01

HLA-B locus products resist degradation by the human cytomegalovirus immunoevasin US11.

by Cosima Zimmermann, Daniel Kowalewski, Liane Bauersfeld, Andreas Hildenbrand, Carolin Gerke, Magdalena Schwarzmüller, Vu Thuy Khanh Le-Trilling, Stefan Stevanovic, Hartmut Hengel, Frank Momburg, Anne Halenius
Published 2019-09-01

Modulation of NKp30- and NKp46-mediated natural killer cell responses by poxviral hemagglutinin.

by Mostafa Jarahian, Manuela Fiedler, André Cohnen, Dominik Djandji, Günter J Hämmerling, Cornelius Gati, Adelheid Cerwenka, Peter C Turner, Richard W Moyer, Carsten Watzl, Hartmut Hengel, Frank Momburg
Published 2011-08-01

Human cytomegalovirus Fcγ binding proteins gp34 and gp68 antagonize Fcγ receptors I, II and III.

by Eugenia Corrales-Aguilar, Mirko Trilling, Katja Hunold, Manuela Fiedler, Vu Thuy Khanh Le, Henrike Reinhard, Katrin Ehrhardt, Eva Mercé-Maldonado, Enver Aliyev, Albert Zimmermann, David C Johnson, Hartmut Hengel
Published 2014-05-01

MicroRNA editing facilitates immune elimination of HCMV infected cells.

by Daphna Nachmani, Albert Zimmermann, Esther Oiknine Djian, Yiska Weisblum, Yoav Livneh, Vu Thuy Khanh Le, Eithan Galun, Vaclav Horejsi, Ofer Isakov, Noam Shomron, Dana G Wolf, Hartmut Hengel, Ofer Mandelboim
Published 2014-02-01

Dynamic Co-evolution of Host and Pathogen: HCMV Downregulates the Prevalent Allele MICA∗008 to Escape Elimination by NK Cells

by Einat Seidel, Vu Thuy Khanh Le, Yotam Bar-On, Pinchas Tsukerman, Jonatan Enk, Rachel Yamin, Natan Stein, Dominik Schmiedel, Esther Oiknine Djian, Yiska Weisblum, Boaz Tirosh, Peter Stastny, Dana G. Wolf, Hartmut Hengel, Ofer Mandelboim
Published 2015-02-01