Histone Deacetylase Inhibitors as Anticancer Drugs

by Tomas Eckschlager, Johana Plch, Marie Stiborova, Jan Hrabeta
Published 2017-07-01

Hypoxia-induced chemoresistance in cancer cells: The role of not only HIF-1

by Helena Doktorova, Jan Hrabeta, Mohamed Ashraf Khalil, Tomas Eckschlager
Published 2015-06-01

Zeptomole electrochemical detection of metallothioneins.

by Vojtech Adam, Jitka Petrlova, Joseph Wang, Tomas Eckschlager, Libuse Trnkova, Rene Kizek
Published 2010-07-01

Serum and tissue zinc in epithelial malignancies: a meta-analysis.

by Jaromir Gumulec, Michal Masarik, Vojtech Adam, Tomas Eckschlager, Ivo Provaznik, Rene Kizek
Published 2014-01-01

MIAT Is an Upstream Regulator of NMYC and the Disruption of the MIAT/NMYC Axis Induces Cell Death in <i>NMYC</i> Amplified Neuroblastoma Cell Lines

by Barbara Feriancikova, Tereza Feglarova, Lenka Krskova, Tomas Eckschlager, Ales Vicha, Jan Hrabeta
Published 2021-03-01

Valproic Acid Increases CD133 Positive Cells that Show Low Sensitivity to Cytostatics in Neuroblastoma.

by Mohamed Ashraf Khalil, Jan Hraběta, Tomáš Groh, Pavel Procházka, Helena Doktorová, Tomáš Eckschlager
Published 2016-01-01

Nanodrugs used in cancer therapy

by Katerina Kopeckova, Tomas Eckschlager, Jakub Sirc, Radka Hobzova, Johana Plch, Jan Hrabeta, Jiri Michalek
Published 2019-06-01

Drug Sequestration in Lysosomes as One of the Mechanisms of Chemoresistance of Cancer Cells and the Possibilities of Its Inhibition

by Jan Hraběta, Marie Belhajová, Hana Šubrtová, Miguel Angel Merlos Rodrigo, Zbyněk Heger, Tomáš Eckschlager
Published 2020-06-01

Serum Metallothioneins in Childhood Tumours — A Potential Prognostic Marker

by Richard Prusa, Tomas Eckschlager, Jan Hrabeta, Rene Kizek, David Hynek, Vojtech Adam, Jarmila Kruseova
Published 2013-06-01

The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells

by Tereza Cerna, Jan Hrabeta, Tomas Eckschlager, Eva Frei, Heinz H. Schmeiser, Volker M. Arlt, Marie Stiborová
Published 2018-01-01

Apoferritin/Vandetanib Association Is Long-Term Stable but Does Not Improve Pharmacological Properties of Vandetanib

by Kateřina Jáklová, Tereza Feglarová, Simona Rex, Zbyněk Heger, Tomáš Eckschlager, Jan Hraběta, Petr Hodek, Matúš Kolárik, Radek Indra
Published 2021-04-01

The Role of Metallothionein in Oxidative Stress

by Rene Kizek, Marie Stiborova, Vojtech Adam, Tomas Eckschlager, Michal Masarik, Ondrej Zitka, Jaromir Gumulec, Branislav Ruttkay-Nedecky, Lukas Nejdl
Published 2013-03-01

A Novel Insight into the Cardiotoxicity of Antineoplastic Drug Doxorubicin

by Zbynek Heger, Natalia Cernei, Jiri Kudr, Jaromir Gumulec, Iva Blazkova, Ondrej Zitka, Tomas Eckschlager, Marie Stiborova, Vojtech Adam, Rene Kizek
Published 2013-10-01

Sarcosine as a Potential Prostate Cancer Biomarker—A Review

by Rene Kizek, Vojtech Adam, Marie Stiborova, Tomas Eckschlager, Petr Babula, Michal Masarik, Ondrej Zitka, Jaromir Gumulec, Natalia Cernei, Zbynek Heger
Published 2013-07-01

Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery

by Vojtech Adam, Marie Stiborova, Rene Kizek, Tomas Eckschlager, Marketa Vaculovicova, Pavel Kopel, Maja Stanisavljevic, Iva Blazkova, Hoai Viet Nguyen, Simona Dostalova
Published 2013-06-01

VPA does not enhance platinum binding to DNA in cisplatin-resistant neuroblastoma cancer cells

by Martina Raudenska, Ludmila Krejcova, Lukas Richtera, Zbynek Heger, Jan Hrabeta, Tomas Eckschlager, Marie Stiborova, Vojtech Adam, Monika Kratochvilova, Michal Masarik, Jaromir Gumulec
Published 2017-09-01

Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation

by Radek Indra, Petr Pompach, Václav Martínek, Paulína Takácsová, Katarína Vavrová, Zbyněk Heger, Vojtěch Adam, Tomáš Eckschlager, Kateřina Kopečková, Volker Manfred Arlt, Marie Stiborová
Published 2019-07-01

Modern Micro and Nanoparticle-Based Imaging Techniques

by Jozef Kaiser, Marie Stiborova, Jaromir Hubalek, Tomas Eckschlager, Vojtech Adam, Petr Babula, David Hynek, Pavel Kopel, Jana Drbohlavova, Jana Chomoucka, Marketa Ryvolova, Rene Kizek
Published 2012-11-01

Sarcosine Up-Regulates Expression of Genes Involved in Cell Cycle Progression of Metastatic Models of Prostate Cancer.

by Zbynek Heger, Miguel Angel Merlos Rodrigo, Petr Michalek, Hana Polanska, Michal Masarik, Vitezslav Vit, Mariana Plevova, Dalibor Pacik, Tomas Eckschlager, Marie Stiborova, Vojtech Adam
Published 2016-01-01

The Application of Curve Fitting on the Voltammograms of Various Isoforms of Metallothioneins–Metal Complexes

by Miguel Angel Merlos Rodrigo, Jorge Molina-López, Ana Maria Jimenez Jimenez, Elena Planells Del Pozo, Pavlina Adam, Tomas Eckschlager, Ondrej Zitka, Lukas Richtera, Vojtech Adam
Published 2017-03-01