Histone Deacetylase Inhibitors as Anticancer Drugs

by Tomas Eckschlager, Johana Plch, Marie Stiborova, Jan Hrabeta
Published 2017-07-01

Hypoxia-induced chemoresistance in cancer cells: The role of not only HIF-1

by Helena Doktorova, Jan Hrabeta, Mohamed Ashraf Khalil, Tomas Eckschlager
Published 2015-06-01

MIAT Is an Upstream Regulator of NMYC and the Disruption of the MIAT/NMYC Axis Induces Cell Death in <i>NMYC</i> Amplified Neuroblastoma Cell Lines

by Barbara Feriancikova, Tereza Feglarova, Lenka Krskova, Tomas Eckschlager, Ales Vicha, Jan Hrabeta
Published 2021-03-01

Valproic Acid Increases CD133 Positive Cells that Show Low Sensitivity to Cytostatics in Neuroblastoma.

by Mohamed Ashraf Khalil, Jan Hraběta, Tomáš Groh, Pavel Procházka, Helena Doktorová, Tomáš Eckschlager
Published 2016-01-01

Nanodrugs used in cancer therapy

by Katerina Kopeckova, Tomas Eckschlager, Jakub Sirc, Radka Hobzova, Johana Plch, Jan Hrabeta, Jiri Michalek
Published 2019-06-01

Drug Sequestration in Lysosomes as One of the Mechanisms of Chemoresistance of Cancer Cells and the Possibilities of Its Inhibition

by Jan Hraběta, Marie Belhajová, Hana Šubrtová, Miguel Angel Merlos Rodrigo, Zbyněk Heger, Tomáš Eckschlager
Published 2020-06-01

Serum Metallothioneins in Childhood Tumours — A Potential Prognostic Marker

by Richard Prusa, Tomas Eckschlager, Jan Hrabeta, Rene Kizek, David Hynek, Vojtech Adam, Jarmila Kruseova
Published 2013-06-01

The Histone Deacetylase Inhibitor Valproic Acid Exerts a Synergistic Cytotoxicity with the DNA-Damaging Drug Ellipticine in Neuroblastoma Cells

by Tereza Cerna, Jan Hrabeta, Tomas Eckschlager, Eva Frei, Heinz H. Schmeiser, Volker M. Arlt, Marie Stiborová
Published 2018-01-01

Apoferritin/Vandetanib Association Is Long-Term Stable but Does Not Improve Pharmacological Properties of Vandetanib

by Kateřina Jáklová, Tereza Feglarová, Simona Rex, Zbyněk Heger, Tomáš Eckschlager, Jan Hraběta, Petr Hodek, Matúš Kolárik, Radek Indra
Published 2021-04-01

Multimutated Herpes Simplex Virus G207 Is a Potent Inhibitor of Angiogenesis

by Jindrich Cinatl, Jr., Martin Michaelis, Pablo Hernáiz Drievert, Jaroslav Cinatl, Jan Hrabeta, Tatyana Suhan, Hans Wilhelm Doerr, Jens-Uwe Vogel
Published 2004-11-01

VPA does not enhance platinum binding to DNA in cisplatin-resistant neuroblastoma cancer cells

by Martina Raudenska, Ludmila Krejcova, Lukas Richtera, Zbynek Heger, Jan Hrabeta, Tomas Eckschlager, Marie Stiborova, Vojtech Adam, Monika Kratochvilova, Michal Masarik, Jaromir Gumulec
Published 2017-09-01

An Adsorptive Transfer Technique Coupled with Brdicka Reaction to Reveal the Importance of Metallothionein in Chemotherapy with Platinum Based Cytostatics

by Libuse Trnkova, Rene Kizek, Richard Prusa, Denisa Darsova, Jiri Kukacka, Tomas Eckschlager, Pavel Pochop, Jan Hrabeta, Petr Babula, Vojtech Adam, Dalibor Huska, Ivo Fabrik, Sona Krizkova
Published 2010-11-01