Striking differences in virulence, transmission and sporocyst growth dynamics between two schistosome populations

by Winka Le Clecʼh, Robbie Diaz, Frédéric D. Chevalier, Marina McDew-White, Timothy J. C. Anderson
Published 2019-10-01

The distribution of intestinal helminth infections in a rural village in Guatemala

by Timothy J. C. Anderson, Claire A. Zizza, Guisela M. Leche, Marilyn E. Scott, Noel W. Solomons
Published 1993-03-01

Identity-by-descent with uncertainty characterises connectivity of Plasmodium falciparum populations on the Colombian-Pacific coast.

by Aimee R Taylor, Diego F Echeverry, Timothy J C Anderson, Daniel E Neafsey, Caroline O Buckee
Published 2020-11-01

Genetic architecture of transmission stage production and virulence in schistosome parasites

by Winka Le Clec’h, Frédéric D. Chevalier, Marina McDew-White, Vinay Menon, Grace-Ann Arya, Timothy J.C. Anderson
Published 2021-01-01

Landscape genetics reveals focal transmission of a human macroparasite.

by Charles D Criscione, Joel D Anderson, Dan Sudimack, Janardan Subedi, Ram P Upadhayay, Bharat Jha, Kimberly D Williams, Sarah Williams-Blangero, Timothy J C Anderson
Published 2010-04-01

Quantifying connectivity between local Plasmodium falciparum malaria parasite populations using identity by descent.

by Aimee R Taylor, Stephen F Schaffner, Gustavo C Cerqueira, Standwell C Nkhoma, Timothy J C Anderson, Kanlaya Sriprawat, Aung Pyae Phyo, François Nosten, Daniel E Neafsey, Caroline O Buckee
Published 2017-10-01

Pairwise growth competitions identify relative fitness relationships among artemisinin resistant Plasmodium falciparum field isolates

by Abigail R. Tirrell, Katelyn M. Vendrely, Lisa A. Checkley, Sage Z. Davis, Marina McDew-White, Ian H. Cheeseman, Ashley M. Vaughan, François H. Nosten, Timothy J. C. Anderson, Michael T. Ferdig
Published 2019-08-01

Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?

by Anastasia R. Rugel, Meghan A. Guzman, Alexander B. Taylor, Frédéric D. Chevalier, Reid S. Tarpley, Stanton F. McHardy, Xiaohang Cao, Stephen P. Holloway, Timothy J.C. Anderson, P. John Hart, Philip T. LoVerde
Published 2020-08-01

Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine.

by Alexander B Taylor, Livia Pica-Mattoccia, Chiara M Polcaro, Enrica Donati, Xiaohang Cao, Annalisa Basso, Alessandra Guidi, Anastasia R Rugel, Stephen P Holloway, Timothy J C Anderson, P John Hart, Donato Cioli, Philip T LoVerde
Published 2015-01-01

An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans.

by Meghan A Guzman, Anastasia R Rugel, Reid S Tarpley, Sevan N Alwan, Frédéric D Chevalier, Dmytro P Kovalskyy, Xiaohang Cao, Stephen P Holloway, Timothy J C Anderson, Alexander B Taylor, Stanton F McHardy, Philip T LoVerde
Published 2020-08-01

Longitudinal genomic surveillance of Plasmodium falciparum malaria parasites reveals complex genomic architecture of emerging artemisinin resistance

by Gustavo C. Cerqueira, Ian H. Cheeseman, Steve F. Schaffner, Shalini Nair, Marina McDew-White, Aung Pyae Phyo, Elizabeth A. Ashley, Alexandre Melnikov, Peter Rogov, Bruce W. Birren, François Nosten, Timothy J. C. Anderson, Daniel E. Neafsey
Published 2017-04-01

The extended recovery ring-stage survival assay provides a superior association with patient clearance half-life and increases throughput

by Sage Z. Davis, Puspendra P. Singh, Katelyn M. Vendrely, Douglas A. Shoue, Lisa A. Checkley, Marina McDew-White, Katrina A. Button-Simons, Zione Cassady, Mackenzie A. C. Sievert, Gabriel J. Foster, François H. Nosten, Timothy J. C. Anderson, Michael T. Ferdig
Published 2020-01-01

The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice

by Katrina A. Button-Simons, Sudhir Kumar, Nelly Carmago, Meseret T. Haile, Catherine Jett, Lisa A. Checkley, Spencer Y. Kennedy, Richard S. Pinapati, Douglas A. Shoue, Marina McDew-White, Xue Li, François H. Nosten, Stefan H. Kappe, Timothy J. C. Anderson, Jeanne Romero-Severson, Michael T. Ferdig, Scott J. Emrich, Ashley M. Vaughan, Ian H. Cheeseman
Published 2021-06-01

Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment.

by Frédéric D Chevalier, Winka Le Clec'h, Marina McDew-White, Vinay Menon, Meghan A Guzman, Stephen P Holloway, Xiaohang Cao, Alexander B Taylor, Safari Kinung'hi, Anouk N Gouvras, Bonnie L Webster, Joanne P Webster, Aidan M Emery, David Rollinson, Amadou Garba Djirmay, Khalid M Al Mashikhi, Salem Al Yafae, Mohamed A Idris, Hélène Moné, Gabriel Mouahid, P John Hart, Philip T LoVerde, Timothy J C Anderson
Published 2019-10-01