Tamoxifen Derivatives Alter Retromer-Dependent Endosomal Tubulation and Sorting to Block Retrograde Trafficking of Shiga Toxins

by Andrey S. Selyunin, Karinel Nieves-Merced, Danyang Li, Stanton F. McHardy, Somshuvra Mukhopadhyay
Published 2021-06-01

Rational approach to drug discovery for human schistosomiasis

by Philip T. LoVerde, Sevan N. Alwan, Alexander B. Taylor, Jayce Rhodes, Frédéric D. Chevalier, Timothy JC. Anderson, Stanton F. McHardy
Published 2021-08-01

Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans Filamentation

by Jesus A. Romo, Christopher G. Pierce, Ashok K. Chaturvedi, Anna L. Lazzell, Stanton F. McHardy, Stephen P. Saville, Jose L. Lopez-Ribot, Joseph Heitman
Published 2017-12-01

Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?

by Anastasia R. Rugel, Meghan A. Guzman, Alexander B. Taylor, Frédéric D. Chevalier, Reid S. Tarpley, Stanton F. McHardy, Xiaohang Cao, Stephen P. Holloway, Timothy J.C. Anderson, P. John Hart, Philip T. LoVerde
Published 2020-08-01

An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans.

by Meghan A Guzman, Anastasia R Rugel, Reid S Tarpley, Sevan N Alwan, Frédéric D Chevalier, Dmytro P Kovalskyy, Xiaohang Cao, Stephen P Holloway, Timothy J C Anderson, Alexander B Taylor, Stanton F McHardy, Philip T LoVerde
Published 2020-08-01