Identification and evolution of nuclear receptors in Platyhelminths.

by Wenjie Wu, Philip T LoVerde
Published 2021-01-01

Vaccination with antioxidant enzymes confers protective immunity against challenge infection with Schistosoma mansoni

by Philip T LoVerde, Claudia Carvalho-Queiroz, Rosemary Cook
Published 2004-08-01

Schistosoma mansoni TGF-beta receptor II: role in host ligand-induced regulation of a schistosome target gene.

by Ahmed Osman, Edward G Niles, Sergio Verjovski-Almeida, Philip T LoVerde
Published 2006-06-01

Rational approach to drug discovery for human schistosomiasis

by Philip T. LoVerde, Sevan N. Alwan, Alexander B. Taylor, Jayce Rhodes, Frédéric D. Chevalier, Timothy JC. Anderson, Stanton F. McHardy
Published 2021-08-01

The spatial distribution of Schistosoma mansoni infection before and after chemotherapy in the Jequitinhonha Valley in Brazil

by Andrea Gazzinelli, Allen Hightower, Philip T LoVerde, João Paulo Amaral Haddad, Wesley Rodrigues Pereira, Jeffrey Bethony, Rodrigo Correa-Oliveira, Helmut Kloos
Published 2006-10-01

Protective potential of antioxidant enzymes as vaccines for schistosomiasis in a non-human primate model

by Claudia eCarvalho-Queiroz, Ruth eNyakundi, Paul eOgongo, Hitler eRikoi, Nejat K Egilmez, Idle O Farah, Thomas M Kariuki, Philip T LoVerde
Published 2015-06-01

Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?

by Anastasia R. Rugel, Meghan A. Guzman, Alexander B. Taylor, Frédéric D. Chevalier, Reid S. Tarpley, Stanton F. McHardy, Xiaohang Cao, Stephen P. Holloway, Timothy J.C. Anderson, P. John Hart, Philip T. LoVerde
Published 2020-08-01

Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine.

by Alexander B Taylor, Livia Pica-Mattoccia, Chiara M Polcaro, Enrica Donati, Xiaohang Cao, Annalisa Basso, Alessandra Guidi, Anastasia R Rugel, Stephen P Holloway, Timothy J C Anderson, P John Hart, Donato Cioli, Philip T LoVerde
Published 2015-01-01

An iterative process produces oxamniquine derivatives that kill the major species of schistosomes infecting humans.

by Meghan A Guzman, Anastasia R Rugel, Reid S Tarpley, Sevan N Alwan, Frédéric D Chevalier, Dmytro P Kovalskyy, Xiaohang Cao, Stephen P Holloway, Timothy J C Anderson, Alexander B Taylor, Stanton F McHardy, Philip T LoVerde
Published 2020-08-01

A systematically improved high quality genome and transcriptome of the human blood fluke Schistosoma mansoni.

by Anna V Protasio, Isheng J Tsai, Anne Babbage, Sarah Nichol, Martin Hunt, Martin A Aslett, Nishadi De Silva, Giles S Velarde, Tim J C Anderson, Richard C Clark, Claire Davidson, Gary P Dillon, Nancy E Holroyd, Philip T LoVerde, Christine Lloyd, Jacquelline McQuillan, Guilherme Oliveira, Thomas D Otto, Sophia J Parker-Manuel, Michael A Quail, R Alan Wilson, Adhemar Zerlotini, David W Dunne, Matthew Berriman
Published 2012-01-01

Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment.

by Frédéric D Chevalier, Winka Le Clec'h, Marina McDew-White, Vinay Menon, Meghan A Guzman, Stephen P Holloway, Xiaohang Cao, Alexander B Taylor, Safari Kinung'hi, Anouk N Gouvras, Bonnie L Webster, Joanne P Webster, Aidan M Emery, David Rollinson, Amadou Garba Djirmay, Khalid M Al Mashikhi, Salem Al Yafae, Mohamed A Idris, Hélène Moné, Gabriel Mouahid, P John Hart, Philip T LoVerde, Timothy J C Anderson
Published 2019-10-01