The Role of Phlebovirus Glycoproteins in Viral Entry, Assembly and Release

by Martin Spiegel, Teresa Plegge, Stefan Pöhlmann
Published 2016-07-01

Evidence that Processing of the Severe Fever with Thrombocytopenia Syndrome Virus Gn/Gc Polyprotein Is Critical for Viral Infectivity and Requires an Internal Gc Signal Peptide.

by Teresa Plegge, Heike Hofmann-Winkler, Martin Spiegel, Stefan Pöhlmann
Published 2016-01-01

Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of e...

by Teresa Plegge, Martin Spiegel, Nadine Krüger, Inga Nehlmeier, Michael Winkler, Mariana González Hernández, Stefan Pöhlmann
Published 2019-01-01

Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.

by Lennart Michel Reinke, Martin Spiegel, Teresa Plegge, Anika Hartleib, Inga Nehlmeier, Stefanie Gierer, Markus Hoffmann, Heike Hofmann-Winkler, Michael Winkler, Stefan Pöhlmann
Published 2017-01-01