Inhibitors of signal peptide peptidase and subtilisin/kexin-isozyme 1 inhibit Ebola virus glycoprotein-driven cell entry by interfering with activity and cellular localization of e...

by Teresa Plegge, Martin Spiegel, Nadine Krüger, Inga Nehlmeier, Michael Winkler, Mariana González Hernández, Stefan Pöhlmann
Published 2019-01-01

The glycoprotein of vesicular stomatitis virus promotes release of virus-like particles from tetherin-positive cells.

by Constantin Brinkmann, Markus Hoffmann, Anastasia Lübke, Inga Nehlmeier, Annika Krämer-Kühl, Michael Winkler, Stefan Pöhlmann
Published 2017-01-01

Role of rhesus macaque IFITM3(2) in simian immunodeficiency virus infection of macaques.

by Michael Winkler, Sabine Gärtner, Lara Markus, Markus Hoffmann, Inga Nehlmeier, Michael Krawczak, Ulrike Sauermann, Stefan Pöhlmann
Published 2019-01-01

H2 influenza A virus is not pathogenic in Tmprss2 knock-out mice

by Ruth Lydia Olga Lambertz, Ingo Gerhauser, Inga Nehlmeier, Sabine Gärtner, Michael Winkler, Sarah Rebecca Leist, Heike Kollmus, Stefan Pöhlmann, Klaus Schughart
Published 2020-04-01

Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.

by Lennart Michel Reinke, Martin Spiegel, Teresa Plegge, Anika Hartleib, Inga Nehlmeier, Stefanie Gierer, Markus Hoffmann, Heike Hofmann-Winkler, Michael Winkler, Stefan Pöhlmann
Published 2017-01-01

Influenza A virus does not encode a tetherin antagonist with Vpu-like activity and induces IFN-dependent tetherin expression in infected cells.

by Michael Winkler, Stephanie Bertram, Kerstin Gnirß, Inga Nehlmeier, Ali Gawanbacht, Frank Kirchhoff, Christina Ehrhardt, Stephan Ludwig, Miriam Kiene, Anna-Sophie Moldenhauer, Ulrike Goedecke, Christina B Karsten, Annika Kühl, Stefan Pöhlmann
Published 2012-01-01

Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin.

by Pawel Zmora, Paulina Molau-Blazejewska, Stephanie Bertram, Kerstin Walendy-Gnirß, Inga Nehlmeier, Anika Hartleib, Anna-Sophie Moldenhauer, Sebastian Konzok, Susann Dehmel, Katherina Sewald, Constantin Brinkmann, Christoph Curths, Sascha Knauf, Jens Gruber, Kerstin Mätz-Rensing, Franziska Dahlmann, Armin Braun, Stefan Pöhlmann
Published 2017-01-01