Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.

by Lennart Michel Reinke, Martin Spiegel, Teresa Plegge, Anika Hartleib, Inga Nehlmeier, Stefanie Gierer, Markus Hoffmann, Heike Hofmann-Winkler, Michael Winkler, Stefan Pöhlmann
Published 2017-01-01

Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin.

by Pawel Zmora, Paulina Molau-Blazejewska, Stephanie Bertram, Kerstin Walendy-Gnirß, Inga Nehlmeier, Anika Hartleib, Anna-Sophie Moldenhauer, Sebastian Konzok, Susann Dehmel, Katherina Sewald, Constantin Brinkmann, Christoph Curths, Sascha Knauf, Jens Gruber, Kerstin Mätz-Rensing, Franziska Dahlmann, Armin Braun, Stefan Pöhlmann
Published 2017-01-01