Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.

by Anders H Olsson, Petr Volkov, Karl Bacos, Tasnim Dayeh, Elin Hall, Emma A Nilsson, Claes Ladenvall, Tina Rönn, Charlotte Ling
Published 2014-11-01

Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.

by Tasnim Dayeh, Petr Volkov, Sofia Salö, Elin Hall, Emma Nilsson, Anders H Olsson, Clare L Kirkpatrick, Claes B Wollheim, Lena Eliasson, Tina Rönn, Karl Bacos, Charlotte Ling
Published 2014-03-01

A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissue.

by Tina Rönn, Petr Volkov, Cajsa Davegårdh, Tasnim Dayeh, Elin Hall, Anders H Olsson, Emma Nilsson, Asa Tornberg, Marloes Dekker Nitert, Karl-Fredrik Eriksson, Helena A Jones, Leif Groop, Charlotte Ling
Published 2013-06-01

Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

by Karl Bacos, Linn Gillberg, Petr Volkov, Anders H Olsson, Torben Hansen, Oluf Pedersen, Anette Prior Gjesing, Hans Eiberg, Tiinamaija Tuomi, Peter Almgren, Leif Groop, Lena Eliasson, Allan Vaag, Tasnim Dayeh, Charlotte Ling
Published 2016-03-01

A central role for GRB10 in regulation of islet function in man.

by Inga Prokopenko, Wenny Poon, Reedik Mägi, Rashmi Prasad B, S Albert Salehi, Peter Almgren, Peter Osmark, Nabila Bouatia-Naji, Nils Wierup, Tove Fall, Alena Stančáková, Adam Barker, Vasiliki Lagou, Clive Osmond, Weijia Xie, Jari Lahti, Anne U Jackson, Yu-Ching Cheng, Jie Liu, Jeffrey R O'Connell, Paul A Blomstedt, Joao Fadista, Joao Fadista, Sami Alkayyali, Tasnim Dayeh, Emma Ahlqvist, Jalal Taneera, Cecile Lecoeur, Ashish Kumar, Ola Hansson, Karin Hansson, Benjamin F Voight, Hyun Min Kang, Claire Levy-Marchal, Vincent Vatin, Aarno Palotie, Ann-Christine Syvänen, Andrea Mari, Michael N Weedon, Ruth J F Loos, Ken K Ong, Peter Nilsson, Bo Isomaa, Tiinamaija Tuomi, Nicholas J Wareham, Michael Stumvoll, Elisabeth Widen, Timo A Lakka, Claudia Langenberg, Anke Tönjes, Rainer Rauramaa, Johanna Kuusisto, Timothy M Frayling, Philippe Froguel, Mark Walker, Johan G Eriksson, Charlotte Ling, Peter Kovacs, Erik Ingelsson, Mark I McCarthy, Alan R Shuldiner, Kristi D Silver, Markku Laakso, Leif Groop, Valeriya Lyssenko
Published 2014-04-01