Advancing leukemia diagnostics: Role of Next Generation Sequencing (NGS) in acute myeloid leukemia

by Torsten Haferlach
Published 2020-09-01

Clinical application of whole transcriptome sequencing for the classification of patients with acute lymphoblastic leukemia

by Wencke Walter, Rabia Shahswar, Anna Stengel, Manja Meggendorfer, Wolfgang Kern, Torsten Haferlach, Claudia Haferlach
Published 2021-08-01

Molecular characterization of AML with RUNX1-RUNX1T1 at diagnosis and relapse reveals net loss of co-mutations

by Alexander Höllein, Niroshan Nadarajah, Manja Meggendorfer, Sabine Jeromin, Wolfgang Kern, Claudia Haferlach, Torsten Haferlach
Published 2019-02-01

Frequency and prognostic impact of CEBPA proximal, distal and core promoter methylation in normal karyotype AML: a study on 623 cases.

by Annette Fasan, Tamara Alpermann, Claudia Haferlach, Vera Grossmann, Andreas Roller, Alexander Kohlmann, Christiane Eder, Wolfgang Kern, Torsten Haferlach, Susanne Schnittger
Published 2013-01-01

Minimal Residual Disease Diagnostics and Chimerism in the Post-Transplant Period in Acute Myeloid Leukemia

by Ulrike Bacher, Torsten Haferlach, Boris Fehse, Susanne Schnittger, Nicolaus Kröger
Published 2011-01-01

Carbon Nanotube FET Technology for Radio-Frequency Electronics: State-of-the-Art Overview

by Michael Schroter, Martin Claus, Paulius Sakalas, M. Haferlach, Dawei Wang
Published 2013-01-01

Dark-matter matters: Discriminating subtle blood cancers using the darkest DNA.

by Laxmi Parida, Claudia Haferlach, Kahn Rhrissorrakrai, Filippo Utro, Chaya Levovitz, Wolfgang Kern, Niroshan Nadarajah, Sven Twardziok, Stephan Hutter, Manja Meggendorfer, Wencke Walter, Constance Baer, Torsten Haferlach
Published 2019-08-01

Maturation State-Specific Alternative Splicing in <i>FLT3</i>-ITD and NPM1 Mutated AML

by Anna Wojtuszkiewicz, Inge van der Werf, Stephan Hutter, Wencke Walter, Constance Baer, Wolfgang Kern, Jeroen J. W. M. Janssen, Gert J. Ossenkoppele, Claudia Haferlach, Jacqueline Cloos, Torsten Haferlach
Published 2021-08-01

Molecular Diagnostics, Targeted Therapy, and the Indication for Allogeneic Stem Cell Transplantation in Acute Lymphoblastic Leukemia

by Anthony Oyekunle, Torsten Haferlach, Nicolaus Kröger, Evgeny Klyuchnikov, Axel Rolf Zander, Susanne Schnittger, Ulrike Bacher
Published 2011-01-01

Quantitative comparison of microarray experiments with published leukemia related gene expression signatures

by Haferlach Torsten, Thiede Christian, Bullinger Lars, Kohlmann Alexander, Ruckert Christian, Klein Hans-Ulrich, Dugas Martin
Published 2009-12-01

Early prediction of therapy response in patients with acute myeloid leukemia by nucleosomal DNA fragments

by Braess Jan, Schalhorn Andreas, Haferlach Torsten, Stieber Petra, Holdenrieder Stefan, Mueller Susanne, Nagel Dorothea, Seidel Dietrich
Published 2006-05-01

The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops

by Sophie Ottema, Roger Mulet-Lazaro, Claudia Erpelinck-Verschueren, Stanley van Herk, Marije Havermans, Andrea Arricibita Varea, Michael Vermeulen, H. Berna Beverloo, Stefan Gröschel, Torsten Haferlach, Claudia Haferlach, Bas J. Wouters, Eric Bindels, Leonie Smeenk, Ruud Delwel
Published 2021-09-01

Genetic Regulation of Tryptase Production and Clinical Impact: Hereditary Alpha Tryptasemia, Mastocytosis and Beyond

by Bettina Sprinzl, Georg Greiner, Goekhan Uyanik, Michel Arock, Torsten Haferlach, Wolfgang R. Sperr, Peter Valent, Gregor Hoermann
Published 2021-02-01

Clonal Hematopoiesis with Oncogenic Potential (CHOP): Separation from CHIP and Roads to AML

by Peter Valent, Wolfgang Kern, Gregor Hoermann, Jelena D. Milosevic Feenstra, Karl Sotlar, Michael Pfeilstöcker, Ulrich Germing, Wolfgang R. Sperr, Andreas Reiter, Dominik Wolf, Michel Arock, Torsten Haferlach, Hans-Peter Horny
Published 2019-02-01

Clonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy.

by Wiltrud Haaß, Helga Kleiner, Christel Weiß, Claudia Haferlach, Brigitte Schlegelberger, Martin C Müller, Rüdiger Hehlmann, Wolf-Karsten Hofmann, Alice Fabarius, Wolfgang Seifarth, Schweizerische Arbeitsgemeinschaft für Klinische Krebsforschung, German CML Study Group
Published 2015-01-01

Scalable Prediction of Acute Myeloid Leukemia Using High-Dimensional Machine Learning and Blood Transcriptomics

by Stefanie Warnat-Herresthal, Konstantinos Perrakis, Bernd Taschler, Matthias Becker, Kevin Baßler, Marc Beyer, Patrick Günther, Jonas Schulte-Schrepping, Lea Seep, Kathrin Klee, Thomas Ulas, Torsten Haferlach, Sach Mukherjee, Joachim L. Schultze
Published 2020-01-01

Loss of PALB2 predicts poor prognosis in acute myeloid leukemia and suggests novel therapeutic strategies targeting the DNA repair pathway

by Antonella Padella, Maria Chiara Fontana, Giovanni Marconi, Eugenio Fonzi, Elisabetta Petracci, Anna Ferrari, Carmen Baldazzi, Cristina Papayannidis, Andrea Ghelli Luserna Di Rorá, Nicoletta Testoni, Gastone Castellani, Torsten Haferlach, Giovanni Martinelli, Giorgia Simonetti
Published 2021-01-01

JAK/STAT-Activating Genomic Alterations Are a Hallmark of T-PLL

by Linus Wahnschaffe, Till Braun, Sanna Timonen, Anil K. Giri, Alexandra Schrader, Prerana Wagle, Henrikki Almusa, Patricia Johansson, Dorine Bellanger, Cristina López, Claudia Haferlach, Marc-Henri Stern, Jan Dürig, Reiner Siebert, Satu Mustjoki, Tero Aittokallio, Marco Herling
Published 2019-11-01

The Link between Cytogenetics/Genomics and Imaging Patterns of Relapse and Progression in Patients with Relapsed/Refractory Multiple Myeloma: A Pilot Study Utilizing 18F-FDG PET/CT

by Xiang Zhou, Alexander Dierks, Olivia Kertels, Samuel Samnick, Malte Kircher, Andreas K. Buck, Larissa Haertle, Sebastian Knorz, David Böckle, Lukas Scheller, Janin Messerschmidt, Mohammad Barakat, Marietta Truger, Claudia Haferlach, Hermann Einsele, Leo Rasche, K. Martin Kortüm, Constantin Lapa
Published 2020-08-01

Venetoclax with azacitidine targets refractory MDS but spares healthy hematopoiesis at tailored dose

by Stefanie Jilg, Richard T. Hauch, Johanna Kauschinger, Lars Buschhorn, Timo O. Odinius, Veronika Dill, Catharina Müller-Thomas, Tobias Herold, Peter M. Prodinger, Burkhard Schmidt, Dirk Hempel, Florian Bassermann, Christian Peschel, Katharina S. Götze, Ulrike Höckendorf, Torsten Haferlach, Philipp J. Jost
Published 2019-04-01