Bortezomib resistance in multiple myeloma is associated with increased serine synthesis

by Esther A. Zaal, Wei Wu, Gerrit Jansen, Sonja Zweegman, Jacqueline Cloos, Celia R. Berkers
Published 2017-08-01

MRD Tailored Therapy in AML: What We Have Learned So Far

by Lok Lam Ngai, Angèle Kelder, Jeroen J. W. M. Janssen, Gert J. Ossenkoppele, Jacqueline Cloos
Published 2021-01-01

Myeloid Antigen Expression in Childhood Acute Lymphoblastic Leukemia and Its Relevance for Clinical Outcome in Indonesian ALL-2006 Protocol

by Eddy Supriyadi, Anjo J. P. Veerman, Sutaryo, Ignatius Purwanto, Peter M. vd Ven, Jacqueline Cloos
Published 2012-01-01

AML/Normal Progenitor Balance Instead of Total Tumor Load (MRD) Accounts for Prognostic Impact of Flowcytometric Residual Disease in AML

by Diana Hanekamp, Jesse M. Tettero, Gert J. Ossenkoppele, Angèle Kelder, Jacqueline Cloos, Gerrit Jan Schuurhuis
Published 2021-05-01

High frequency of the 3R/3R polymorphism in the thymidylate synthase enhancer region in Indonesian childhood acute lymphoblastic leukemia

by IDG Ugrasena, Sutaryo Sutaryo, Edy Supriadi, Laura Vroling, Jacqueline Cloos, Jan Hendrik Hooijberg, AJP Veerman
Published 2016-10-01

Glucocorticoid Resistant Pediatric Acute Lymphoblastic Leukemia Samples Display Altered Splicing Profile and Vulnerability to Spliceosome Modulation

by Rocco Sciarrillo, Anna Wojtuszkiewicz, Irsan E. Kooi, Leticia G. Leon, Edwin Sonneveld, Roland P. Kuiper, Gerrit Jansen, Elisa Giovannetti, Gertjan J.L. Kaspers, Jacqueline Cloos
Published 2020-03-01

Computational comparison of common event-based differential splicing tools: practical considerations for laboratory researchers

by Ittai B. Muller, Stijn Meijers, Peter Kampstra, Steven van Dijk, Michel van Elswijk, Marry Lin, Anna M. Wojtuszkiewicz, Gerrit Jansen, Robert de Jonge, Jacqueline Cloos
Published 2021-06-01

Pre-Clinical Evaluation of the Proteasome Inhibitor Ixazomib Against Bortezomib-Resistant Leukemia Cells and Primary Acute Leukemia Cells

by Margot S.F. Roeten, Johan van Meerloo, Zinia J. Kwidama, Giovanna ter Huizen, Wouter H. Segerink, Sonja Zweegman, Gertjan J.L. Kaspers, Gerrit Jansen, Jacqueline Cloos
Published 2021-03-01

Maturation State-Specific Alternative Splicing in <i>FLT3</i>-ITD and NPM1 Mutated AML

by Anna Wojtuszkiewicz, Inge van der Werf, Stephan Hutter, Wencke Walter, Constance Baer, Wolfgang Kern, Jeroen J. W. M. Janssen, Gert J. Ossenkoppele, Claudia Haferlach, Jacqueline Cloos, Torsten Haferlach
Published 2021-08-01

Attenuated AMPA receptor expression allows glioblastoma cell survival in glutamate-rich environment.

by Dannis G van Vuurden, Maryam Yazdani, Ingeborg Bosma, Aart J F Broekhuizen, Tjeerd J Postma, Jan J Heimans, Paul van der Valk, Eleonora Aronica, Bakhos A Tannous, Thomas Würdinger, Gertjan J L Kaspers, Jacqueline Cloos
Published 2009-01-01

Down-regulation of miR-101 in endothelial cells promotes blood vessel formation through reduced repression of EZH2.

by Michiel Smits, Shahryar E Mir, R Jonas A Nilsson, Petra M van der Stoop, Johanna M Niers, Victor E Marquez, Jacqueline Cloos, Xandra O Breakefield, Anna M Krichevsky, David P Noske, Bakhos A Tannous, Thomas Würdinger
Published 2011-01-01

Proteasome subunit expression analysis and chemosensitivity in relapsed paediatric acute leukaemia patients receiving bortezomib-containing chemotherapy

by Denise Niewerth, Gertjan J. L. Kaspers, Gerrit Jansen, Johan van Meerloo, Sonja Zweegman, Gaye Jenkins, James A. Whitlock, Stephen P. Hunger, Xiaomin Lu, Todd A. Alonzo, Peter M. van de Ven, Terzah M. Horton, Jacqueline Cloos
Published 2016-09-01

High accuracy mutation detection in leukemia on a selected panel of cancer genes.

by Zeynep Kalender Atak, Kim De Keersmaecker, Valentina Gianfelici, Ellen Geerdens, Roel Vandepoel, Daphnie Pauwels, Michaël Porcu, Idoya Lahortiga, Vanessa Brys, Willy G Dirks, Hilmar Quentmeier, Jacqueline Cloos, Harry Cuppens, Anne Uyttebroeck, Peter Vandenberghe, Jan Cools, Stein Aerts
Published 2012-01-01

Harnessing Gene Expression Profiles for the Identification of Ex Vivo Drug Response Genes in Pediatric Acute Myeloid Leukemia

by David G.J. Cucchi, Costa Bachas, Marry M. van den Heuvel-Eibrink, Susan T.C.J.M. Arentsen-Peters, Zinia J. Kwidama, Gerrit J. Schuurhuis, Yehuda G. Assaraf, Valérie de Haas, Gertjan J.L. Kaspers, Jacqueline Cloos
Published 2020-05-01

Comprehensive analysis of transcriptome variation uncovers known and novel driver events in T-cell acute lymphoblastic leukemia.

by Zeynep Kalender Atak, Valentina Gianfelici, Gert Hulselmans, Kim De Keersmaecker, Arun George Devasia, Ellen Geerdens, Nicole Mentens, Sabina Chiaretti, Kaat Durinck, Anne Uyttebroeck, Peter Vandenberghe, Iwona Wlodarska, Jacqueline Cloos, Robin Foà, Frank Speleman, Jan Cools, Stein Aerts
Published 2013-01-01

Gene expression profiles associated with pediatric relapsed AML.

by Costa Bachas, Gerrit Jan Schuurhuis, C Michel Zwaan, Marry M van den Heuvel-Eibrink, Monique L den Boer, Eveline S J M de Bont, Zinia J Kwidama, Dirk Reinhardt, Ursula Creutzig, Valérie de Haas, Gertjan J L Kaspers, Jacqueline Cloos
Published 2015-01-01

A Meta-Analysis of Retinoblastoma Copy Numbers Refines the List of Possible Driver Genes Involved in Tumor Progression.

by Irsan E Kooi, Berber M Mol, Maarten P G Massink, Marcus C de Jong, Pim de Graaf, Paul van der Valk, Hanne Meijers-Heijboer, Gertjan J L Kaspers, Annette C Moll, Hein Te Riele, Jacqueline Cloos, Josephine C Dorsman
Published 2016-01-01

Phosphoproteomic Characterization of Primary AML Samples and Relevance for Response Toward FLT3-inhibitors

by David G. J. Cucchi, Carolien Van Alphen, Sonja Zweegman, Bo Van Kuijk, Zinia J. Kwidama, Adil al Hinai, Alexander A. Henneman, Jaco C. Knol, Sander R. Piersma, Thang V. Pham, Connie R. Jimenez, Jacqueline Cloos, Jeroen J. W. M. Janssen
Published 2021-07-01

Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features.

by Marcel Kool, Jan Koster, Jens Bunt, Nancy E Hasselt, Arjan Lakeman, Peter van Sluis, Dirk Troost, Netteke Schouten-van Meeteren, Huib N Caron, Jacqueline Cloos, Alan Mrsić, Bauke Ylstra, Wieslawa Grajkowska, Wolfgang Hartmann, Torsten Pietsch, David Ellison, Steven C Clifford, Rogier Versteeg
Published 2008-08-01

Loss of photoreceptorness and gain of genomic alterations in retinoblastoma reveal tumor progression

by Irsan E. Kooi, Berber M. Mol, Annette C. Moll, Paul van der Valk, Marcus C. de Jong, Pim de Graaf, Saskia E. van Mil, Antoinette Y.N. Schouten-van Meeteren, Hanne Meijers-Heijboer, Gertjan L. Kaspers, Hein te Riele, Jacqueline Cloos, Josephine C. Dorsman
Published 2015-07-01