Measurement of separase proteolytic activity in single living cells by a fluorogenic flow cytometry assay.

by Wiltrud Haaß, Helga Kleiner, Martin C Müller, Wolf-Karsten Hofmann, Alice Fabarius, Wolfgang Seifarth
Published 2015-01-01

The proteolytic activity of separase in BCR-ABL-positive cells is increased by imatinib.

by Wiltrud Haaß, Michael Stehle, Stefanie Nittka, Michelle Giehl, Petra Schrotz-King, Alice Fabarius, Wolf-Karsten Hofmann, Wolfgang Seifarth
Published 2012-01-01

Clonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy.

by Wiltrud Haaß, Helga Kleiner, Christel Weiß, Claudia Haferlach, Brigitte Schlegelberger, Martin C Müller, Rüdiger Hehlmann, Wolf-Karsten Hofmann, Alice Fabarius, Wolfgang Seifarth, Schweizerische Arbeitsgemeinschaft für Klinische Krebsforschung, German CML Study Group
Published 2015-01-01