Induction of Chromosomal Instability via Telomere Dysfunction and Epigenetic Alterations in Myeloid Neoplasia

by Brigitte Schlegelberger, Beate Vajen, Kathrin Thomay
Published 2013-07-01

Psychological Distress and Coping Ability of Women at High Risk of Hereditary Breast and Ovarian Cancer before Undergoing Genetic Counseling–An Exploratory Study from Germany

by Beate Vajen, Magdalena Rosset, Hannah Wallaschek, Eva Baumann, Brigitte Schlegelberger
Published 2021-04-01

GABP is necessary for stem/progenitor cell maintenance and myeloid differentiation in human hematopoiesis and chronic myeloid leukemia

by Georgi Manukjan, Tim Ripperger, Letizia Venturini, Michael Stadler, Gudrun Göhring, Axel Schambach, Brigitte Schlegelberger, Doris Steinemann
Published 2016-05-01

Comprehensive MALDI-TOF biotyping of the non-redundant Harvard Pseudomonas aeruginosa PA14 transposon insertion mutant library.

by Tonio Oumeraci, Vanessa Jensen, Steven R Talbot, Winfried Hofmann, Markus Kostrzewa, Brigitte Schlegelberger, Nils von Neuhoff, Susanne Häussler
Published 2015-01-01

Routes of Clonal Evolution into Complex Karyotypes in Myelodysplastic Syndrome Patients with 5q Deletion

by Simone Feurstein, Kathrin Thomay, Winfried Hofmann, Guntram Buesche, Hans Kreipe, Felicitas Thol, Michael Heuser, Arnold Ganser, Brigitte Schlegelberger, Gudrun Göhring
Published 2018-10-01

From a variant of unknown significance to pathogenic: Reclassification of a large novel duplication in BRCA2 by high‐throughput sequencing

by Jana Lisa vanLuttikhuizen, Janin Bublitz, Stephanie Schubert, Gunnar Schmidt, Winfried Hofmann, Susanne Morlot, Reena Buurman, Bernd Auber, Brigitte Schlegelberger, Doris Steinemann
Published 2020-09-01

Monitoring CSF proteome alterations in amyotrophic lateral sclerosis: obstacles and perspectives in translating a novel marker panel to the clinic.

by Nils von Neuhoff, Tonio Oumeraci, Thomas Wolf, Katja Kollewe, Peter Bewerunge, Boris Neumann, Benedikt Brors, Johannes Bufler, Ulrich Wurster, Brigitte Schlegelberger, Reinhard Dengler, Marc Zapatka, Susanne Petri
Published 2012-01-01

Radiation rescue: mesenchymal stromal cells protect from lethal irradiation.

by Claudia Lange, Bärbel Brunswig-Spickenheier, Heike Cappallo-Obermann, Katharina Eggert, Ursula M Gehling, Cornelia Rudolph, Brigitte Schlegelberger, Kerstin Cornils, Jozef Zustin, Andrej-Nikolai Spiess, Axel R Zander
Published 2011-01-01

Breast cancer patients suggestive of Li-Fraumeni syndrome: mutational spectrum, candidate genes, and unexplained heredity

by Judith Penkert, Gunnar Schmidt, Winfried Hofmann, Stephanie Schubert, Maximilian Schieck, Bernd Auber, Tim Ripperger, Karl Hackmann, Marc Sturm, Holger Prokisch, Ursula Hille-Betz, Dorothea Mark, Thomas Illig, Brigitte Schlegelberger, Doris Steinemann
Published 2018-08-01

Clonal Evolution and Blast Crisis Correlate with Enhanced Proteolytic Activity of Separase in BCR-ABL b3a2 Fusion Type CML under Imatinib Therapy.

by Wiltrud Haaß, Helga Kleiner, Christel Weiß, Claudia Haferlach, Brigitte Schlegelberger, Martin C Müller, Rüdiger Hehlmann, Wolf-Karsten Hofmann, Alice Fabarius, Wolfgang Seifarth, Schweizerische Arbeitsgemeinschaft für Klinische Krebsforschung, German CML Study Group
Published 2015-01-01

The Clinical Utility of Optical Genome Mapping for the Assessment of Genomic Aberrations in Acute Lymphoblastic Leukemia

by Jonathan Lukas Lühmann, Marie Stelter, Marie Wolter, Josephine Kater, Jana Lentes, Anke Katharina Bergmann, Maximilian Schieck, Gudrun Göhring, Anja Möricke, Gunnar Cario, Markéta Žaliová, Martin Schrappe, Brigitte Schlegelberger, Martin Stanulla, Doris Steinemann
Published 2021-08-01

Establishment and Characterization of a Sclerosing Spindle Cell Rhabdomyosarcoma Cell Line with a Complex Genomic Profile

by Sabine Schleicher, Stefan Grote, Elke Malenke, Kenneth Chun-Ho Chan, Martin Schaller, Birgit Fehrenbacher, Rosa Riester, Torsten Kluba, Leonie Frauenfeld, Hans Boesmueller, Gudrun Göhring, Brigitte Schlegelberger, Rupert Handgretinger, Hans-Georg Kopp, Frank Traub, Karen A. Boehme
Published 2020-12-01

Plasma Metabolome Signature Indicative of BRCA1 Germline Status Independent of Cancer Incidence

by Judith Penkert, Andre Märtens, Martin Seifert, Bernd Auber, Katja Derlin, Ursula Hille-Betz, Philipp Hörmann, Norman Klopp, Jana Prokein, Lisa Schlicker, Frank Wacker, Hannah Wallaschek, Brigitte Schlegelberger, Karsten Hiller, Karsten Hiller, Tim Ripperger, Thomas Illig, Thomas Illig
Published 2021-04-01

Prevalence of pathogenic BRCA1/2 germline mutations among 802 women with unilateral triple-negative breast cancer without family cancer history

by Christoph Engel, Kerstin Rhiem, Eric Hahnen, Sibylle Loibl, Karsten E. Weber, Sabine Seiler, Silke Zachariae, Jan Hauke, Barbara Wappenschmidt, Anke Waha, Britta Blümcke, Marion Kiechle, Alfons Meindl, Dieter Niederacher, Claus R. Bartram, Dorothee Speiser, Brigitte Schlegelberger, Norbert Arnold, Peter Wieacker, Elena Leinert, Andrea Gehrig, Susanne Briest, Karin Kast, Olaf Riess, Günter Emons, Bernhard H. F. Weber, Jutta Engel, Rita K. Schmutzler, on behalf of the German Consortium for Hereditary Breast and Ovarian Cancer (GC-HBOC)
Published 2018-03-01

The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants

by Ana Rio-Machin, Tom Vulliamy, Nele Hug, Amanda Walne, Kiran Tawana, Shirleny Cardoso, Alicia Ellison, Nikolas Pontikos, Jun Wang, Hemanth Tummala, Ahad Fahad H. Al Seraihi, Jenna Alnajar, Findlay Bewicke-Copley, Hannah Armes, Michael Barnett, Adrian Bloor, Csaba Bödör, David Bowen, Pierre Fenaux, Andrew Green, Andrew Hallahan, Henrik Hjorth-Hansen, Upal Hossain, Sally Killick, Sarah Lawson, Mark Layton, Alison M. Male, Judith Marsh, Priyanka Mehta, Rogier Mous, Josep F. Nomdedéu, Carolyn Owen, Jiri Pavlu, Elspeth M. Payne, Rachel E. Protheroe, Claude Preudhomme, Nuria Pujol-Moix, Aline Renneville, Nigel Russell, Anand Saggar, Gabriela Sciuccati, David Taussig, Cynthia L. Toze, Anne Uyttebroeck, Peter Vandenberghe, Brigitte Schlegelberger, Tim Ripperger, Doris Steinemann, John Wu, Joanne Mason, Paula Page, Susanna Akiki, Kim Reay, Jamie D. Cavenagh, Vincent Plagnol, Javier F. Caceres, Jude Fitzgibbon, Inderjeet Dokal
Published 2020-02-01