Sensing Lipids with Mincle: Structure and Function

by Spencer J. Williams
Published 2017-11-01

A practical synthesis of long-chain iso-fatty acids (iso-C12–C19) and related natural products

by Mark B. Richardson, Spencer J. Williams
Published 2013-09-01

MCL and mincle: C-type lectin receptors that sense damaged self and pathogen associated molecular patterns

by Mark B Richardson, Spencer J Williams
Published 2014-06-01

Synthesis of glycoconjugate fragments of mycobacterial phosphatidylinositol mannosides and lipomannan

by Benjamin Cao, Jonathan M. White, Spencer J. Williams
Published 2011-03-01

Glutathione contributes to efficient post-Golgi trafficking of incoming HPV16 genome.

by Shuaizhi Li, Matthew P Bronnimann, Spencer J Williams, Samuel K Campos
Published 2019-01-01

Galanin-3 Receptor Antagonism by SNAP 37889 Reduces Motivation to Self-administer Alcohol and Attenuates Cue-Induced Reinstatement of Alcohol-Seeking in iP Rats

by Belinda L. Ash, Tim Quach, Spencer J. Williams, Andrew J. Lawrence, Elvan Djouma
Published 2014-01-01

An improved method to prepare an injectable microemulsion of the galanin-receptor 3 selective antagonist, SNAP 37889, using Kolliphor® HS 15

by Karlene J. Scheller, Spencer J. Williams, Andrew J. Lawrence, Bevyn Jarrott, Elvan Djouma
Published 2014-01-01

Discovery of inhibitors of Leishmania β-1,2-mannosyltransferases using a click-chemistry-derived guanosine monophosphate library.

by Phillip van der Peet, Julie E Ralton, Malcolm J McConville, Spencer J Williams
Published 2012-01-01

Localization of oleuropeyl glucose esters and a flavanone to secretory cavities of Myrtaceae.

by Allison M Heskes, Jason Q D Goodger, Sammi Tsegay, Tim Quach, Spencer J Williams, Ian E Woodrow
Published 2012-01-01

A purpose-synthesised anti-fibrotic agent attenuates experimental kidney diseases in the rat.

by Richard E Gilbert, Yuan Zhang, Spencer J Williams, Steven C Zammit, David I Stapleton, Alison J Cox, Henry Krum, Robyn Langham, Darren J Kelly
Published 2012-01-01

Inhibition of DYRK1A disrupts neural lineage specificationin human pluripotent stem cells

by Stephanie F Bellmaine, Dmitry A Ovchinnikov, David T Manallack, Claire E Cuddy, Andrew G Elefanty, Edouard G Stanley, Ernst J Wolvetang, Spencer J Williams, Martin Pera
Published 2017-09-01

Diazepam is not a direct allosteric modulator of α1‐adrenoceptors, but modulates receptor signaling by inhibiting phosphodiesterase‐4

by Lisa M. Williams, Xiaoji He, Tasneem M. Vaid, Alaa Abdul‐Ridha, Alice R. Whitehead, Paul R. Gooley, Ross A.D. Bathgate, Spencer J. Williams, Daniel J. Scott
Published 2019-02-01

Gram scale preparation of clozapine N-oxide (CNO), a synthetic small molecule actuator for muscarinic acetylcholine DREADDs

by Phillip L. van der Peet, Christian Gunawan, Alaa Abdul-Ridha, Sherie Ma, Daniel J. Scott, Andrew L. Gundlach, Ross A.D. Bathgate, Jonathan M. White, Spencer J. Williams
Published 2018-01-01

Lipidomic Profiling of Adipose Tissue Reveals an Inflammatory Signature in Cancer-Related and Primary Lymphedema.

by Lisa M Sedger, Dedreia L Tull, Malcolm J McConville, David P De Souza, Thusitha W T Rupasinghe, Spencer J Williams, Saravanan Dayalan, Daniel Lanzer, Helen Mackie, Thomas C Lam, John Boyages
Published 2016-01-01

A β‑Mannanase with a Lysozyme-like Fold and a Novel Molecular Catalytic Mechanism

by Yi Jin, Marija Petricevic, Alan John, Lluís Raich, Huw Jenkins, Leticia Portela De Souza, Fiona Cuskin, Harry J. Gilbert, Carme Rovira, Ethan D. Goddard-Borger, Spencer J. Williams, Gideon J. Davies
Published 2016-11-01

The Metabolite Repair Enzyme Phosphoglycolate Phosphatase Regulates Central Carbon Metabolism and Fosmidomycin Sensitivity in Plasmodium falciparum

by Laure Dumont, Mark B. Richardson, Phillip van der Peet, Danushka S. Marapana, Tony Triglia, Matthew W. A. Dixon, Alan F. Cowman, Spencer J. Williams, Leann Tilley, Malcolm J. McConville, Simon A. Cobbold
Published 2019-12-01

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors

by Catarina F. Almeida, Srinivasan Sundararaj, Jérôme Le Nours, T. Praveena, Benjamin Cao, Satvika Burugupalli, Dylan G. M. Smith, Onisha Patel, Manfred Brigl, Daniel G. Pellicci, Spencer J. Williams, Adam P. Uldrich, Dale I. Godfrey, Jamie Rossjohn
Published 2019-11-01