Deterioration of Organ Function As a Hallmark in Sepsis: The Cellular Perspective

by Michael Bauer, Michael Bauer, Sina M. Coldewey, Sina M. Coldewey, Sina M. Coldewey, Margit Leitner, Bettina Löffler, Bettina Löffler, Sebastian Weis, Sebastian Weis, Sebastian Weis, Reinhard Wetzker
Published 2018-06-01

Identification and Antibiotic Profiling of Wohlfahrtiimonas chitiniclastica, an Underestimated Human Pathogen

by Anna Kopf, Boyke Bunk, Sina M. Coldewey, Sina M. Coldewey, Florian Gunzer, Thomas Riedel, Thomas Riedel, Percy Schröttner
Published 2021-09-01

A Pilot Study on the Association of Mitochondrial Oxygen Metabolism and Gas Exchange During Cardiopulmonary Exercise Testing: Is There a Mitochondrial Threshold?

by Philipp Baumbach, Philipp Baumbach, Christiane Schmidt-Winter, Christiane Schmidt-Winter, Jan Hoefer, Jan Hoefer, Steffen Derlien, Norman Best, Marco Herbsleb, Sina M. Coldewey, Sina M. Coldewey, Sina M. Coldewey
Published 2020-12-01

A Narrative Review on the Role of AMPK on De Novo Lipogenesis in Non-Alcoholic Fatty Liver Disease: Evidence from Human Studies

by Christian von Loeffelholz, Sina M. Coldewey, Andreas L. Birkenfeld
Published 2021-07-01

Inhibition of IκB kinase reduces the multiple organ dysfunction caused by sepsis in the mouse

by Sina M. Coldewey, Mara Rogazzo, Massimo Collino, Nimesh S. A. Patel, Christoph Thiemermann
Published 2013-07-01

Non-invasive Assessment of Mitochondrial Oxygen Metabolism in the Critically Ill Patient Using the Protoporphyrin IX-Triplet State Lifetime Technique—A Feasibility Study

by Charles Neu, Charles Neu, Charles Neu, Philipp Baumbach, Philipp Baumbach, Alina K. Plooij, Alina K. Plooij, Kornel Skitek, Kornel Skitek, Juliane Götze, Juliane Götze, Christian von Loeffelholz, Christiane Schmidt-Winter, Christiane Schmidt-Winter, Sina M. Coldewey, Sina M. Coldewey, Sina M. Coldewey
Published 2020-05-01

Infliximab against severe COVID-19-induced cytokine storm syndrome with organ failure—a cautionary case series

by Andreas Stallmach, Andreas Kortgen, Falk Gonnert, Sina M. Coldewey, Philipp Reuken, Michael Bauer
Published 2020-07-01

Downregulation of S1P Lyase Improves Barrier Function in Human Cerebral Microvascular Endothelial Cells Following an Inflammatory Challenge

by Bisera Stepanovska, Antonia I. Lange, Stephanie Schwalm, Josef Pfeilschifter, Sina M. Coldewey, Andrea Huwiler
Published 2020-02-01

Gender dimorphism of the cardiac dysfunction in murine sepsis: signalling mechanisms and age-dependency.

by Jianmin Chen, Fausto Chiazza, Massimo Collino, Nimesh S A Patel, Sina M Coldewey, Christoph Thiemermann
Published 2014-01-01

Modeling Hemolytic-Uremic Syndrome: In-Depth Characterization of Distinct Murine Models Reflecting Different Features of Human Disease

by Sophie Dennhardt, Sophie Dennhardt, Sophie Dennhardt, Wiebke Pirschel, Wiebke Pirschel, Bianka Wissuwa, Bianka Wissuwa, Christoph Daniel, Florian Gunzer, Sandro Lindig, Anna Medyukhina, Michael Kiehntopf, Wolfram W. Rudolph, Peter F. Zipfel, Matthias Gunzer, Marc Thilo Figge, Marc Thilo Figge, Marc Thilo Figge, Kerstin Amann, Sina M. Coldewey, Sina M. Coldewey, Sina M. Coldewey
Published 2018-06-01

Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice

by Caroline E. O'Riordan, Gareth S. D. Purvis, Debora Collotta, Fausto Chiazza, Bianka Wissuwa, Bianka Wissuwa, Sura Al Zoubi, Lara Stiehler, Lara Stiehler, Lukas Martin, Lukas Martin, Sina M. Coldewey, Sina M. Coldewey, Massimo Collino, Christoph Thiemermann
Published 2019-09-01

X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure

by Caroline E. O'Riordan, Gareth S. D. Purvis, Debora Collotta, Nadine Krieg, Nadine Krieg, Bianka Wissuwa, Bianka Wissuwa, Madeeha H. Sheikh, Gustavo Ferreira Alves, Shireen Mohammad, Lauren A. Callender, Sina M. Coldewey, Sina M. Coldewey, Massimo Collino, David R. Greaves, Christoph Thiemermann
Published 2020-10-01

Erythropoietin attenuates cardiac dysfunction in experimental sepsis in mice via activation of the β-common receptor

by Areeg I. Khan, Sina M. Coldewey, Nimesh S. A. Patel, Mara Rogazzo, Massimo Collino, Muhammed M. Yaqoob, Peter Radermacher, Amar Kapoor, Christoph Thiemermann
Published 2013-07-01

Use of IFNγ/IL10 Ratio for Stratification of Hydrocortisone Therapy in Patients With Septic Shock

by Rainer König, Rainer König, Amol Kolte, Amol Kolte, Olaf Ahlers, Marcus Oswald, Marcus Oswald, Veiko Krauss, Veiko Krauss, Daniela Roell, Daniela Roell, Oliver Sommerfeld, George Dimopoulos, Iraklis Tsangaris, Eleni Antoniadou, Neeraja Jaishankar, Holger Bogatsch, Markus Löffler, Markus Rödel, Marina Garcia-Moreno, Lorena Tuchscherr, Charles L. Sprung, Mervyn Singer, Frank Brunkhorst, Michael Oppert, Herwig Gerlach, Ralf A. Claus, Sina M. Coldewey, Sina M. Coldewey, Sina M. Coldewey, Josef Briegel, Evangelos J. Giamarellos-Bourboulis, Evangelos J. Giamarellos-Bourboulis, Didier Keh, Michael Bauer, Michael Bauer
Published 2021-03-01

A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice

by Shireen Mohammad, Sura Al Zoubi, Sura Al Zoubi, Debora Collotta, Nadine Krieg, Nadine Krieg, Bianka Wissuwa, Bianka Wissuwa, Gustavo Ferreira Alves, Gareth S. D. Purvis, Gareth S. D. Purvis, Giuseppe Danilo Norata, Giuseppe Danilo Norata, Giuseppe Danilo Norata, Andrea Baragetti, Andrea Baragetti, Alberico Luigi Catapano, Alberico Luigi Catapano, Alberico Luigi Catapano, Egle Solito, Egle Solito, Elisabeth Zechendorf, Tobias Schürholz, Wilmar Correa-Vargas, Klaus Brandenburg, Sina M. Coldewey, Sina M. Coldewey, Massimo Collino, Muhammad M. Yaqoob, Lukas Martin, Lukas Martin, Christoph Thiemermann
Published 2021-07-01

Targeted delivery of a phosphoinositide 3‐kinase γ inhibitor to restore organ function in sepsis

by Adrian T Press, Petra Babic, Bianca Hoffmann, Tina Müller, Wanling Foo, Walter Hauswald, Jovana Benecke, Martina Beretta, Zoltán Cseresnyés, Stephanie Hoeppener, Ivo Nischang, Sina M Coldewey, Markus H Gräler, Reinhard Bauer, Falk Gonnert, Nikolaus Gaßler, Reinhard Wetzker, Marc Thilo Figge, Ulrich S Schubert, Michael Bauer
Published 2021-10-01

Comparison of clinical and immunological findings in gnotobiotic piglets infected with Escherichia coli O104:H4 outbreak strain and EHEC O157:H7

by Bettina Wöchtl, Florian Gunzer, Wilhelm Gerner, Hagen Gasse, Michaela Koch, Zoltán Bagó, Martin Ganter, Herbert Weissenböck, Nora Dinhopl, Sina M. Coldewey, Alexandra von Altrock, Karl-Heinz Waldmann, Armin Saalmüller, Kurt Zimmermann, Jörg Steinmann, Jan Kehrmann, Ludger Klein-Hitpass, Jochen Blom, Ralf Ehricht, Ines Engelmann, Isabel Hennig-Pauka
Published 2017-05-01

Identification of Brain-Specific Treatment Effects in NPC1 Disease by Focusing on Cellular and Molecular Changes of Sphingosine-1-Phosphate Metabolism

by Anne Gläser, Franziska Hammerl, Markus H. Gräler, Sina M. Coldewey, Christin Völkner, Moritz J. Frech, Fan Yang, Jiankai Luo, Eric Tönnies, Oliver von Bohlen und Halbach, Nicola Brandt, Diana Heimes, Anna-Maria Neßlauer, Georg Christoph Korenke, Marta Owczarek-Lipska, John Neidhardt, Arndt Rolfs, Andreas Wree, Martin Witt, Anja Ursula Bräuer
Published 2020-06-01