Another Round of “Clue” to Uncover the Mystery of Complex Traits

by Shefali Setia Verma, Marylyn D. Ritchie
Published 2018-01-01

A simulation study investigating power estimates in phenome-wide association studies

by Anurag Verma, Yuki Bradford, Scott Dudek, Anastasia M. Lucas, Shefali S. Verma, Sarah A. Pendergrass, Marylyn D. Ritchie
Published 2018-04-01

Collective feature selection to identify crucial epistatic variants

by Shefali S. Verma, Anastasia Lucas, Xinyuan Zhang, Yogasudha Veturi, Scott Dudek, Binglan Li, Ruowang Li, Ryan Urbanowicz, Jason H. Moore, Dokyoon Kim, Marylyn D. Ritchie
Published 2018-04-01

Genetics of height and risk of atrial fibrillation: A Mendelian randomization study.

by Michael G Levin, Renae Judy, Dipender Gill, Marijana Vujkovic, Shefali S Verma, Yuki Bradford, Regeneron Genetics Center, Marylyn D Ritchie, Matthew C Hyman, Saman Nazarian, Daniel J Rader, Benjamin F Voight, Scott M Damrauer
Published 2020-10-01

PLATO software provides analytic framework for investigating complexity beyond genome-wide association studies

by Molly A. Hall, John Wallace, Anastasia Lucas, Dokyoon Kim, Anna O. Basile, Shefali S. Verma, Cathy A. McCarty, Murray H. Brilliant, Peggy L. Peissig, Terrie E. Kitchner, Anurag Verma, Sarah A. Pendergrass, Scott M. Dudek, Jason H. Moore, Marylyn D. Ritchie
Published 2017-10-01

A GWAS Study on Liver Function Test Using eMERGE Network Participants.

by Bahram Namjou, Keith Marsolo, Todd Lingren, Marylyn D Ritchie, Shefali S Verma, Beth L Cobb, Cassandra Perry, Terrie E Kitchner, Murray H Brilliant, Peggy L Peissig, Kenneth M Borthwick, Marc S Williams, Jane Grafton, Gail P Jarvik, Ingrid A Holm, John B Harley
Published 2015-01-01

Effect of <em>CYP3A4</em>*22 and <em>PPAR-α</em> Genetic Variants on Platelet Reactivity in Patients Treated with Clopidogrel and Lipid-Lowering Drugs Undergoing Elective Percutane...

by Thomas O. Bergmeijer, Alfi Yasmina, Gerrit J. A. Vos, Paul W. A. Janssen, Christian M. Hackeng, Johannes C. Kelder, Shefali S. Verma, Marylyn D. Ritchie, Li Gong, Teri E. Klein, ICPC investigators, Anthonius de Boer, Olaf H. Klungel, Jurriën M. ten Berg, Vera H. M. Deneer
Published 2020-09-01

Epistatic Gene-Based Interaction Analyses for Glaucoma in eMERGE and NEIGHBOR Consortium.

by Shefali Setia Verma, Jessica N Cooke Bailey, Anastasia Lucas, Yuki Bradford, James G Linneman, Michael A Hauser, Louis R Pasquale, Peggy L Peissig, Murray H Brilliant, Catherine A McCarty, Jonathan L Haines, Janey L Wiggs, Tamara R Vrabec, Gerard Tromp, Marylyn D Ritchie, eMERGE Network, NEIGHBOR Consortium
Published 2016-09-01

Novel EDGE encoding method enhances ability to identify genetic interactions.

by Molly A Hall, John Wallace, Anastasia M Lucas, Yuki Bradford, Shefali S Verma, Bertram Müller-Myhsok, Kristin Passero, Jiayan Zhou, John McGuigan, Beibei Jiang, Sarah A Pendergrass, Yanfei Zhang, Peggy Peissig, Murray Brilliant, Patrick Sleiman, Hakon Hakonarson, John B Harley, Krzysztof Kiryluk, Kristel Van Steen, Jason H Moore, Marylyn D Ritchie
Published 2021-06-01

Imputation and quality control steps for combining multiple genome-wide datasets

by Shefali S Verma, Mariza ede Andrade, Gerard eTromp, Helena eKuivaniemi, Elizabeth ePugh, Bahram eNamjou, Shubhabrata eMukherjee, Gail P Jarvik, Leah Claire Kottyan, Amber eBurt, Yuki eBradford, Gretta D Armstrong, Kimberly eDerr, Dana eCrawford, Jonathan L Haines, Rongling eLi, David eCrosslin, Marylyn D Ritchie
Published 2014-12-01

Controlling for population structure and genotyping platform bias in the eMERGE multi-institutional biobank linked to Electronic Health Records

by David Russell Crosslin, David Russell Crosslin, Gerard eTromp, Amber eBurt, Daniel Seung Kim, Shefali S Verma, Anastasia M. Lucas, Yuki eBradford, Dana C. Crawford, Dana C. Crawford, Sebastian M. Armasu, John A. Heit, M. Geoffrey Hayes, Helena eKuivaniemi, Marylyn D Ritchie, Gail P. Jarvik, Gail P. Jarvik, Mariza eDe Andrade
Published 2014-11-01

Medical records-based chronic kidney disease phenotype for clinical care and “big data” observational and genetic studies

by Ning Shang, Atlas Khan, Fernanda Polubriaginof, Francesca Zanoni, Karla Mehl, David Fasel, Paul E. Drawz, Robert J. Carrol, Joshua C. Denny, Matthew A. Hathcock, Adelaide M. Arruda-Olson, Peggy L. Peissig, Richard A. Dart, Murray H. Brilliant, Eric B. Larson, David S. Carrell, Sarah Pendergrass, Shefali Setia Verma, Marylyn D. Ritchie, Barbara Benoit, Vivian S. Gainer, Elizabeth W. Karlson, Adam S. Gordon, Gail P. Jarvik, Ian B. Stanaway, David R. Crosslin, Sumit Mohan, Iuliana Ionita-Laza, Nicholas P. Tatonetti, Ali G. Gharavi, George Hripcsak, Chunhua Weng, Krzysztof Kiryluk
Published 2021-04-01

A study paradigm integrating prospective epidemiologic cohorts and electronic health records to identify disease biomarkers

by Jonathan D. Mosley, QiPing Feng, Quinn S. Wells, Sara L. Van Driest, Christian M. Shaffer, Todd L. Edwards, Lisa Bastarache, Wei-Qi Wei, Lea K. Davis, Catherine A. McCarty, Will Thompson, Christopher G. Chute, Gail P. Jarvik, Adam S. Gordon, Melody R. Palmer, David R. Crosslin, Eric B. Larson, David S. Carrell, Iftikhar J. Kullo, Jennifer A. Pacheco, Peggy L. Peissig, Murray H. Brilliant, James G. Linneman, Bahram Namjou, Marc S. Williams, Marylyn D. Ritchie, Kenneth M. Borthwick, Shefali S. Verma, Jason H. Karnes, Scott T. Weiss, Thomas J. Wang, C. Michael Stein, Josh C. Denny, Dan M. Roden
Published 2018-08-01

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

by Emily R. Holzinger, Shefali S. Verma, Carrie B. Moore, Molly Hall, Rishika De, Diane Gilbert-Diamond, Matthew B. Lanktree, Nathan Pankratz, Antoinette Amuzu, Amber Burt, Caroline Dale, Scott Dudek, Clement E. Furlong, Tom R. Gaunt, Daniel Seung Kim, Helene Riess, Suthesh Sivapalaratnam, Vinicius Tragante, Erik P.A. van Iperen, Ariel Brautbar, David S. Carrell, David R. Crosslin, Gail P. Jarvik, Helena Kuivaniemi, Iftikhar J. Kullo, Eric B. Larson, Laura J. Rasmussen-Torvik, Gerard Tromp, Jens Baumert, Karen J. Cruickshanks, Martin Farrall, Aroon D. Hingorani, G. K. Hovingh, Marcus E. Kleber, Barbara E. Klein, Ronald Klein, Wolfgang Koenig, Leslie A. Lange, Winfried Mӓrz, Kari E. North, N. Charlotte Onland-Moret, Alex P. Reiner, Philippa J. Talmud, Yvonne T. van der Schouw, James G. Wilson, Mika Kivimaki, Meena Kumari, Jason H. Moore, Fotios Drenos, Folkert W. Asselbergs, Brendan J. Keating, Marylyn D. Ritchie
Published 2017-07-01