Editorial: FDA-Approved Drug Repositioning for P-Glycoprotein Overexpressing Resistant Cancer

by Sungpil Yoon, Xiaoju Wang, Sompong Vongpunsawad, Gerard Tromp, Helena Kuivaniemi
Published 2021-03-01

Update on Abdominal Aortic Aneurysm Research: From Clinical to Genetic Studies

by Helena Kuivaniemi, Evan J. Ryer, James R. Elmore, Irene Hinterseher, Diane T. Smelser, Gerard Tromp
Published 2014-01-01

Smooth muscle cell-specific Notch1 haploinsufficiency restricts the progression of abdominal aortic aneurysm by modulating CTGF expression.

by Jaspreet Sachdeva, Advitiya Mahajan, Jeeyun Cheng, Jeremy T Baeten, Brenda Lilly, Helena Kuivaniemi, Chetan P Hans
Published 2017-01-01

Transcriptional (ChIP-Chip) Analysis of ELF1, ETS2, RUNX1 and STAT5 in Human Abdominal Aortic Aneurysm

by Matthew C. Pahl, Robert Erdman, Helena Kuivaniemi, John H. Lillvis, James R. Elmore, Gerard Tromp
Published 2015-05-01

Systematic Review of Genetic Factors in the Etiology of Esophageal Squamous Cell Carcinoma in African Populations

by Hannah Simba, Helena Kuivaniemi, Vittoria Lutje, Gerard Tromp, Gerard Tromp, Gerard Tromp, Gerard Tromp, Gerard Tromp, Vikash Sewram
Published 2019-08-01

Immunohistochemical Analysis of the Natural Killer Cell Cytotoxicity Pathway in Human Abdominal Aortic Aneurysms

by Irene Hinterseher, Charles M. Schworer, John H. Lillvis, Elizabeth Stahl, Robert Erdman, Zoran Gatalica, Gerard Tromp, Helena Kuivaniemi
Published 2015-05-01

Association of simple renal cysts and chronic kidney disease with large abdominal aortic aneurysm

by Milena Miszczuk, Verena Müller, Christian E. Althoff, Andrea Stroux, Daniela Widhalm, Andy Dobberstein, Andreas Greiner, Helena Kuivaniemi, Irene Hinterseher
Published 2020-05-01

Phenome-Wide Association Study to Explore Relationships between Immune System Related Genetic Loci and Complex Traits and Diseases.

by Anurag Verma, Anna O Basile, Yuki Bradford, Helena Kuivaniemi, Gerard Tromp, David Carey, Glenn S Gerhard, James E Crowe, Marylyn D Ritchie, Sarah A Pendergrass
Published 2016-01-01

The Potential Role of DNA Methylation in Abdominal Aortic Aneurysms

by Evan J. Ryer, Kaitryn E. Ronning, Robert Erdman, Charles M. Schworer, James R. Elmore, Thomas C. Peeler, Christopher D. Nevius, John H. Lillvis, Robert P. Garvin, David P. Franklin, Helena Kuivaniemi, Gerard Tromp
Published 2015-05-01

Targeted next-generation sequencing identifies novel variants in candidate genes for Parkinson’s disease in Black South African and Nigerian patients

by Oluwafemi G. Oluwole, Helena Kuivaniemi, Shameemah Abrahams, William L. Haylett, Alvera A. Vorster, Carel J. van Heerden, Colin P. Kenyon, David L. Tabb, Michael B. Fawale, Taofiki A. Sunmonu, Abiodun Ajose, Matthew O. Olaogun, Anastasia C. Rossouw, Ludo S. van Hillegondsberg, Jonathan Carr, Owen A. Ross, Morenikeji A. Komolafe, Gerard Tromp, Soraya Bardien
Published 2020-02-01

The Peripheral Blood Transcriptome Is Correlated With PET Measures of Lung Inflammation During Successful Tuberculosis Treatment

by Trust Odia, Trust Odia, Trust Odia, Trust Odia, Trust Odia, Stephanus T. Malherbe, Stephanus T. Malherbe, Stephanus T. Malherbe, Stuart Meier, Stuart Meier, Stuart Meier, Stuart Meier, Stuart Meier, Elizna Maasdorp, Elizna Maasdorp, Elizna Maasdorp, Elizna Maasdorp, Elizna Maasdorp, Léanie Kleynhans, Léanie Kleynhans, Léanie Kleynhans, Nelita du Plessis, Nelita du Plessis, Nelita du Plessis, Andre G. Loxton, Andre G. Loxton, Andre G. Loxton, Daniel E. Zak, Ethan Thompson, Fergal J. Duffy, Fergal J. Duffy, Helena Kuivaniemi, Helena Kuivaniemi, Helena Kuivaniemi, Katharina Ronacher, Katharina Ronacher, Katharina Ronacher, Katharina Ronacher, Jill Winter, Gerhard Walzl, Gerhard Walzl, Gerhard Walzl, Gerhard Walzl, Gerard Tromp, Gerard Tromp, Gerard Tromp, Gerard Tromp, Gerard Tromp, the Catalysis TB-Biomarker Consortium, André G. Loxton, Annare Ellman, Bronwyn Smith, Caroline G. G. Beltran, Clifton E. Barry, David Alland, Friedrich Thienemann, Gerard Tromp, Gerhard Walzl, James M. Warwick, Jill Winter, Katharina Ronacher, Kim Stanley, Ilse Kant, Lani Thiart, Lance A. Lucas, Laura E. Via, Lori E. Dodd, Magdalena Kriel, Nelita Plessis Du, Patrick Dupont, Ray Y. Chen, Robert J. Wilkinson, Shubhada Shenai, Stephanie Griffith-Richards, Stephanus T. Malherbe
Published 2021-02-01

A Trans-Ethnic Genome-Wide Association Study of Uterine Fibroids

by Todd L. Edwards, Todd L. Edwards, Todd L. Edwards, Ayush Giri, Ayush Giri, Ayush Giri, Jacklyn N. Hellwege, Jacklyn N. Hellwege, Jacklyn N. Hellwege, Katherine E. Hartmann, Katherine E. Hartmann, Elizabeth A. Stewart, Janina M. Jeff, Michael J. Bray, Sarah A. Pendergrass, Eric S. Torstenson, Eric S. Torstenson, Eric S. Torstenson, Jacob M. Keaton, Jacob M. Keaton, Jacob M. Keaton, Sarah H. Jones, Sarah H. Jones, Radhika P. Gogoi, Helena Kuivaniemi, Helena Kuivaniemi, Kathryn L. Jackson, Abel N. Kho, Iftikhar J. Kullo, Catherine A. McCarty, Hae Kyung Im, Jennifer A. Pacheco, Jyotishman Pathak, Marc S. Williams, Gerard Tromp, Gerard Tromp, Eimear E. Kenny, Eimear E. Kenny, Peggy L. Peissig, Joshua C. Denny, Dan M. Roden, Digna R. Velez Edwards, Digna R. Velez Edwards, Digna R. Velez Edwards
Published 2019-06-01

Mechanistic phenotypes: an aggregative phenotyping strategy to identify disease mechanisms using GWAS data.

by Jonathan D Mosley, Sara L Van Driest, Emma K Larkin, Peter E Weeke, John S Witte, Quinn S Wells, Jason H Karnes, Yan Guo, Lisa Bastarache, Lana M Olson, Catherine A McCarty, Jennifer A Pacheco, Gail P Jarvik, David S Carrell, Eric B Larson, David R Crosslin, Iftikhar J Kullo, Gerard Tromp, Helena Kuivaniemi, David J Carey, Marylyn D Ritchie, Josh C Denny, Dan M Roden
Published 2013-01-01

Discovery and replication of SNP-SNP interactions for quantitative lipid traits in over 60,000 individuals

by Emily R. Holzinger, Shefali S. Verma, Carrie B. Moore, Molly Hall, Rishika De, Diane Gilbert-Diamond, Matthew B. Lanktree, Nathan Pankratz, Antoinette Amuzu, Amber Burt, Caroline Dale, Scott Dudek, Clement E. Furlong, Tom R. Gaunt, Daniel Seung Kim, Helene Riess, Suthesh Sivapalaratnam, Vinicius Tragante, Erik P.A. van Iperen, Ariel Brautbar, David S. Carrell, David R. Crosslin, Gail P. Jarvik, Helena Kuivaniemi, Iftikhar J. Kullo, Eric B. Larson, Laura J. Rasmussen-Torvik, Gerard Tromp, Jens Baumert, Karen J. Cruickshanks, Martin Farrall, Aroon D. Hingorani, G. K. Hovingh, Marcus E. Kleber, Barbara E. Klein, Ronald Klein, Wolfgang Koenig, Leslie A. Lange, Winfried Mӓrz, Kari E. North, N. Charlotte Onland-Moret, Alex P. Reiner, Philippa J. Talmud, Yvonne T. van der Schouw, James G. Wilson, Mika Kivimaki, Meena Kumari, Jason H. Moore, Fotios Drenos, Folkert W. Asselbergs, Brendan J. Keating, Marylyn D. Ritchie
Published 2017-07-01