Building the Partners HealthCare Biobank at Partners Personalized Medicine: Informed Consent, Return of Research Results, Recruitment Lessons and Operational Considerations

by Elizabeth W. Karlson, Natalie T. Boutin, Alison G. Hoffnagle, Nicole L. Allen
Published 2016-01-01

Adverse obstetric and neonatal outcomes complicated by psychosis among pregnant women in the United States

by Qiu-Yue Zhong, Bizu Gelaye, Gregory L. Fricchione, Paul Avillach, Elizabeth W. Karlson, Michelle A. Williams
Published 2018-05-01

Genetic risk score predicting risk of rheumatoid arthritis phenotypes and age of symptom onset.

by Lori B Chibnik, Brendan T Keenan, Jing Cui, Katherine P Liao, Karen H Costenbader, Robert M Plenge, Elizabeth W Karlson
Published 2011-01-01

Screening pregnant women for suicidal behavior in electronic medical records: diagnostic codes vs. clinical notes processed by natural language processing

by Qiu-Yue Zhong, Elizabeth W. Karlson, Bizu Gelaye, Sean Finan, Paul Avillach, Jordan W. Smoller, Tianxi Cai, Michelle A. Williams
Published 2018-05-01

An eMERGE Clinical Center at Partners Personalized Medicine

by Jordan W. Smoller, Elizabeth W. Karlson, Robert C. Green, Sekar Kathiresan, Daniel G. MacArthur, Michael E. Talkowski, Shawn N. Murphy, Scott T. Weiss
Published 2016-01-01

Joint effects of colorectal cancer susceptibility loci, circulating 25-hydroxyvitamin D and risk of colorectal cancer.

by Linda T Hiraki, Amit D Joshi, Kimmie Ng, Charles S Fuchs, Jing Ma, Aditi Hazra, Ulrike Peters, Elizabeth W Karlson, Edward Giovannucci, Peter Kraft, Andrew T Chan
Published 2014-01-01

Association of fish intake and smoking with risk of rheumatoid arthritis and age of onset: a prospective cohort study

by Jeffrey A. Sparks, Éilis J. O’Reilly, Medha Barbhaiya, Sara K. Tedeschi, Susan Malspeis, Bing Lu, Walter C. Willett, Karen H. Costenbader, Elizabeth W. Karlson
Published 2019-01-01

Automatic prediction of rheumatoid arthritis disease activity from the electronic medical records.

by Chen Lin, Elizabeth W Karlson, Helena Canhao, Helena Canhao, Timothy A Miller, Dmitriy Dligach, Pei Jun Chen, Raul Natanael Guzman Perez, Yuanyan Shen, Michael E Weinblatt, Nancy A Shadick, Robert M Plenge, Guergana K Savova
Published 2013-01-01

Asthma and elevation of anti-citrullinated protein antibodies prior to the onset of rheumatoid arthritis

by Alessandra Zaccardelli, Xinyi Liu, Julia A. Ford, Jing Cui, Bing Lu, Su H. Chu, Peter H. Schur, Cameron B. Speyer, Karen H. Costenbader, William H. Robinson, Jeremy Sokolove, Elizabeth W. Karlson, Carlos A. Camargo, Jeffrey A. Sparks
Published 2019-11-01

Implementation of Electronic Consent at a Biobank: An Opportunity for Precision Medicine Research

by Natalie T. Boutin, Kathleen Mathieu, Alison G. Hoffnagle, Nicole L. Allen, Victor M. Castro, Megan Morash, P. Pearl O’Rourke, Elizabeth L. Hohmann, Neil Herring, Lynn Bry, Susan A. Slaugenhaupt, Elizabeth W. Karlson, Scott T. Weiss, Jordan W. Smoller
Published 2016-06-01

Methods to Develop an Electronic Medical Record Phenotype Algorithm to Compare the Risk of Coronary Artery Disease across 3 Chronic Disease Cohorts.

by Katherine P Liao, Ashwin N Ananthakrishnan, Vishesh Kumar, Zongqi Xia, Andrew Cagan, Vivian S Gainer, Sergey Goryachev, Pei Chen, Guergana K Savova, Denis Agniel, Susanne Churchill, Jaeyoung Lee, Shawn N Murphy, Robert M Plenge, Peter Szolovits, Isaac Kohane, Stanley Y Shaw, Elizabeth W Karlson, Tianxi Cai
Published 2015-01-01

Modeling disease severity in multiple sclerosis using electronic health records.

by Zongqi Xia, Elizabeth Secor, Lori B Chibnik, Riley M Bove, Suchun Cheng, Tanuja Chitnis, Andrew Cagan, Vivian S Gainer, Pei J Chen, Katherine P Liao, Stanley Y Shaw, Ashwin N Ananthakrishnan, Peter Szolovits, Howard L Weiner, Elizabeth W Karlson, Shawn N Murphy, Guergana K Savova, Tianxi Cai, Susanne E Churchill, Robert M Plenge, Isaac S Kohane, Philip L De Jager
Published 2013-01-01

Hypertension prevalence in the All of Us Research Program among groups traditionally underrepresented in medical research

by Paulette D. Chandler, Cheryl R. Clark, Guohai Zhou, Nyia L. Noel, Confidence Achilike, Lizette Mendez, Andrea H. Ramirez, Roxana Loperena-Cortes, Kelsey Mayo, Elizabeth Cohn, Lucila Ohno-Machado, Eric Boerwinkle, Mine Cicek, Jun Qian, Sheri Schully, Francis Ratsimbazafy, Stephen Mockrin, Kelly Gebo, Julien J. Dedier, Shawn N. Murphy, Jordan W. Smoller, Elizabeth W. Karlson, the All of Us Research Program Investigators
Published 2021-06-01

TRAF1/C5 but Not PTPRC Variants Are Potential Predictors of Rheumatoid Arthritis Response to Anti-Tumor Necrosis Factor Therapy

by Helena Canhão, Ana Maria Rodrigues, Maria José Santos, Diana Carmona-Fernandes, Bruno F. Bettencourt, Jing Cui, Fabiana L. Rocha, José Canas Silva, Joaquim Polido-Pereira, José Alberto Pereira Silva, José António Costa, Domingos Araujo, Cândida Silva, Helena Santos, Cátia Duarte, Rafael Cáliz, Ileana Filipescu, Fernando Pimentel-Santos, Jaime Branco, Juan Sainz, Robert M. Plenge, Daniel H. Solomon, Jácome Bruges-Armas, José António P. Da Silva, João Eurico Fonseca, Elizabeth W. Karlson
Published 2015-01-01

Medical records-based chronic kidney disease phenotype for clinical care and “big data” observational and genetic studies

by Ning Shang, Atlas Khan, Fernanda Polubriaginof, Francesca Zanoni, Karla Mehl, David Fasel, Paul E. Drawz, Robert J. Carrol, Joshua C. Denny, Matthew A. Hathcock, Adelaide M. Arruda-Olson, Peggy L. Peissig, Richard A. Dart, Murray H. Brilliant, Eric B. Larson, David S. Carrell, Sarah Pendergrass, Shefali Setia Verma, Marylyn D. Ritchie, Barbara Benoit, Vivian S. Gainer, Elizabeth W. Karlson, Adam S. Gordon, Gail P. Jarvik, Ian B. Stanaway, David R. Crosslin, Sumit Mohan, Iuliana Ionita-Laza, Nicholas P. Tatonetti, Ali G. Gharavi, George Hripcsak, Chunhua Weng, Krzysztof Kiryluk
Published 2021-04-01

TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits.

by Dorothée Diogo, Lisa Bastarache, Katherine P Liao, Robert R Graham, Robert S Fulton, Jeffrey D Greenberg, Steve Eyre, John Bowes, Jing Cui, Annette Lee, Dimitrios A Pappas, Joel M Kremer, Anne Barton, Marieke J H Coenen, Barbara Franke, Lambertus A Kiemeney, Xavier Mariette, Corrine Richard-Miceli, Helena Canhão, João E Fonseca, Niek de Vries, Paul P Tak, J Bart A Crusius, Michael T Nurmohamed, Fina Kurreeman, Ted R Mikuls, Yukinori Okada, Eli A Stahl, David E Larson, Tracie L Deluca, Michelle O'Laughlin, Catrina C Fronick, Lucinda L Fulton, Roman Kosoy, Michael Ransom, Tushar R Bhangale, Ward Ortmann, Andrew Cagan, Vivian Gainer, Elizabeth W Karlson, Isaac Kohane, Shawn N Murphy, Javier Martin, Alexandra Zhernakova, Lars Klareskog, Leonid Padyukov, Jane Worthington, Elaine R Mardis, Michael F Seldin, Peter K Gregersen, Timothy Behrens, Soumya Raychaudhuri, Joshua C Denny, Robert M Plenge
Published 2015-01-01

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis.

by Jing Cui, Eli A Stahl, Saedis Saevarsdottir, Corinne Miceli, Dorothee Diogo, Gosia Trynka, Towfique Raj, Maša Umiċeviċ Mirkov, Helena Canhao, Helena Canhao, Katsunori Ikari, Chikashi Terao, Yukinori Okada, Sara Wedrén, Johan Askling, Hisashi Yamanaka, Shigeki Momohara, Atsuo Taniguchi, Koichiro Ohmura, Fumihiko Matsuda, Tsuneyo Mimori, Namrata Gupta, Manik Kuchroo, Ann W Morgan, John D Isaacs, Anthony G Wilson, Kimme L Hyrich, Marieke Herenius, Marieke E Doorenspleet, Paul-Peter Tak, J Bart A Crusius, Irene E van der Horst-Bruinsma, Gert Jan Wolbink, Piet L C M van Riel, Mart van de Laar, Henk-Jan Guchelaar, Nancy A Shadick, Cornelia F Allaart, Tom W J Huizinga, Rene E M Toes, Robert P Kimberly, S Louis Bridges, Lindsey A Criswell, Larry W Moreland, João Eurico Fonseca, Niek de Vries, Barbara E Stranger, Philip L De Jager, Soumya Raychaudhuri, Michael E Weinblatt, Peter K Gregersen, Xavier Mariette, Anne Barton, Leonid Padyukov, Marieke J H Coenen, Elizabeth W Karlson, Robert M Plenge
Published 2013-03-01