Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression

by Martina Proctor, Jazmina L. Gonzalez Cruz, Sheena M. Daignault-Mill, Margaret Veitch, Bijun Zeng, Anna Ehmann, Muhammed Sabdia, Cameron Snell, Colm Keane, Riccardo Dolcetti, Nikolas K. Haass, James W. Wells, Brian Gabrielli
Published 2021-07-01

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine

by Zay Yar Oo, Martina Proctor, Alexander J. Stevenson, Deborah Nazareth, Madushan Fernando, Sheena M. Daignault, Catherine Lanagan, Sebastian Walpole, Vanessa Bonazzi, Dubravka Škalamera, Cameron Snell, Nikolas K. Haass, Jill E. Larsen, Brian Gabrielli
Published 2019-07-01