Dysregulated G2 phase checkpoint recovery pathway reduces DNA repair efficiency and increases chromosomal instability in a wide range of tumours

by Madushan Fernando, Pascal H. G. Duijf, Martina Proctor, Alexander J. Stevenson, Anna Ehmann, Shivam Vora, Dubravka Skalamera, Mark Adams, Brian Gabrielli
Published 2021-05-01

Targeting Replication Stress Using CHK1 Inhibitor Promotes Innate and NKT Cell Immune Responses and Tumour Regression

by Martina Proctor, Jazmina L. Gonzalez Cruz, Sheena M. Daignault-Mill, Margaret Veitch, Bijun Zeng, Anna Ehmann, Muhammed Sabdia, Cameron Snell, Colm Keane, Riccardo Dolcetti, Nikolas K. Haass, James W. Wells, Brian Gabrielli
Published 2021-07-01

Host Porphobilinogen Deaminase Deficiency Confers Malaria Resistance in Plasmodium chabaudi but Not in Plasmodium berghei or Plasmodium falciparum During Intraerythrocytic Growth

by Cilly Bernardette Schnider, Cilly Bernardette Schnider, Hao Yang, Lora Starrs, Anna Ehmann, Farid Rahimi, Elena Di Pierro, Giovanna Graziadei, Kathryn Matthews, Tania De Koning-Ward, Denis C. Bauer, Simon J. Foote, Gaetan Burgio, Brendan J. McMorran
Published 2020-09-01