Pathophysiology and Treatment Strategies of Acute Myopathy and Muscle Wasting after Sepsis

by Robert T. Mankowski, Orlando Laitano, Thomas L. Clanton, Scott C. Brakenridge
Published 2021-04-01

Immunological Endotyping of Chronic Critical Illness After Severe Sepsis

by Brittany P. Fenner, D. B. Darden, Lauren S. Kelly, Jaimar Rincon, Scott C. Brakenridge, Shawn D. Larson, Frederick A. Moore, Philip A. Efron, Lyle L. Moldawer
Published 2021-02-01

Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study

by Julie A. Stortz, Michael C. Cox, Russell B. Hawkins, Gabriela L. Ghita, Babette A. Brumback, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron, Scott C. Brakenridge, Frederick A. Moore
Published 2020-05-01

In Vitro–Administered Dexamethasone Suppresses T Cell Function With Reversal by Interleukin-7 in Coronavirus Disease 2019

by Monty B. Mazer, MD, Ethan Davitt, , BS, Isaiah R. Turnbull, MD, PhD, Charles C. Caldwell, PhD, Scott C. Brakenridge, MD, Kenneth E. Remy, MD, MHSc, MSCI, Richard S. Hotchkiss, MD
Published 2021-04-01

Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome

by Russell B. Hawkins, Steven L. Raymond, Julie A. Stortz, Hiroyuki Horiguchi, Scott C. Brakenridge, Anna Gardner, Philip A. Efron, Azra Bihorac, Azra Bihorac, Mark Segal, Mark Segal, Frederick A. Moore, Lyle L. Moldawer
Published 2018-07-01

Prognostic value of NT-proBNP levels in the acute phase of sepsis on lower long-term physical function and muscle strength in sepsis survivors

by Carlo Custodero, Quran Wu, Gabriela L. Ghita, Stephen D. Anton, Scott C. Brakenridge, Babette A. Brumback, Philip A. Efron, Anna K. Gardner, Christiaan Leeuwenburgh, Lyle L. Moldawer, John W. Petersen, Frederick A. Moore, Robert T. Mankowski
Published 2019-06-01

Sepsis is associated with reduced spontaneous neutrophil migration velocity in human adults.

by Steven L Raymond, Russell B Hawkins, Julie A Stortz, Tyler J Murphy, Ricardo Ungaro, Marvin L Dirain, Dina C Nacionales, McKenzie K Hollen, Jaimar C Rincon, Shawn D Larson, Scott C Brakenridge, Frederick A Moore, Daniel Irimia, Phil A Efron, Lyle L Moldawer
Published 2018-01-01

Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy

by Hiroyuki Horiguchi, Hiroyuki Horiguchi, Tyler J. Loftus, Russell B. Hawkins, Steven L. Raymond, Julie A. Stortz, McKenzie K. Hollen, Brett P. Weiss, Elizabeth S. Miller, Azra Bihorac, Shawn D. Larson, Alicia M. Mohr, Scott C. Brakenridge, Hironori Tsujimoto, Hideki Ueno, Frederick A. Moore, Lyle L. Moldawer, Philip A. Efron, The Sepsis and Critical Illness Research Center Investigators
Published 2018-04-01

Chronic Critical Illness Elicits a Unique Circulating Leukocyte Transcriptome in Sepsis Survivors

by Dijoia B. Darden, Gabriela L. Ghita, Zhongkai Wang, Julie A. Stortz, Maria-Cecilia Lopez, Michael C. Cox, Russell B. Hawkins, Jaimar C. Rincon, Lauren S. Kelly, Brittany P. Fenner, Tezcan Ozrazgat-Baslanti, Christiaan Leeuwenburgh, Azra Bihorac, Tyler J. Loftus, Frederick A. Moore, Scott C. Brakenridge, Henry V. Baker, Rhonda Bacher, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron
Published 2021-07-01

Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

by Kenneth E. Remy, Monty Mazer, David A. Striker, Ali H. Ellebedy, Andrew H. Walton, Jacqueline Unsinger, Teresa M. Blood, Philip A. Mudd, Daehan J. Yi, Daniel A. Mannion, Dale F. Osborne, R. Scott Martin, Nitin J. Anand, James P. Bosanquet, Jane Blood, Anne M. Drewry, Charles C. Caldwell, Isaiah R. Turnbull, Scott C. Brakenridge, Lyle L. Moldwawer, Richard S. Hotchkiss
Published 2021-02-01

Identification of Unique mRNA and miRNA Expression Patterns in Bone Marrow Hematopoietic Stem and Progenitor Cells After Trauma in Older Adults

by Dijoia B. Darden, Julie A. Stortz, McKenzie K. Hollen, Michael C. Cox, Camille G. Apple, Russell B. Hawkins, Jaimar C. Rincon, Maria-Cecilia Lopez, Zhongkai Wang, Eduardo Navarro, Jennifer E. Hagen, Hari K. Parvataneni, Maigan A. Brusko, Michael Kladde, Rhonda Bacher, Babette A. Brumback, Scott C. Brakenridge, Henry V. Baker, Christopher R. Cogle, Alicia M. Mohr, Philip A. Efron
Published 2020-06-01

Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3: A Case Report

by Monty B. Mazer, MD, Isaiah R. Turnbull, MD, PhD, Sydney Miles, BS, Teresa M. Blood, BS, Brooke Sadler, PhD, Annie Hess, MD, Mitchell D. Botney, MD, Robert S. Martin, MD, James P. Bosanquet, MD, David A. Striker, MD, Nitin S. Anand, MD, Michel Morre, DVM, MSc, Charles C. Caldwell, PhD, Scott C. Brakenridge, MD, MSCS, Lyle L. Moldawer, PhD, Jorge A. Di Paola, MD, Richard S. Hotchkiss, MD, Kenneth E. Remy, MD, MHSc, MSCI
Published 2021-07-01

Severe Acute Respiratory Syndrome–Associated Coronavirus 2 Infection and Organ Dysfunction in the ICU: Opportunities for Translational Research

by Philip A. Verhoef, MD, PhD, Sujatha Kannan, MD, Jamie L. Sturgill, PhD, Elizabeth W. Tucker, MD, Peter E. Morris, MD, Andrew C. Miller, MD, Travis R. Sexton, PhD, Jay L. Koyner, MD, Rana Hejal, MD, Scott C. Brakenridge, MD, Lyle L. Moldawer, PhD, Richard S. Hotchkiss, MD, Teresa M. Blood, BS, Monty B. Mazer, MD, Scott Bolesta, PharmD, Sheila A. Alexander, PhD, RN, Donna Lee Armaignac, PhD, Steven L. Shein, MD, Christopher Jones, MD, Caroline D. Hoemann, PhD, Allan Doctor, MD, Stuart H. Friess, MD, Robert I. Parker, MD, Alexandre T. Rotta, MD, Kenneth E. Remy, MD, MHSC, MSCI, for the Basic and Translational Science Committee of the Research Section for the Society of Critical Care Medicine
Published 2021-03-01