Sepsis and Cognitive Assessment

by Laura C. Jones, Catherine Dion, Philip A. Efron, Catherine C. Price
Published 2021-09-01

Dysregulated Immunity and Immunotherapy after Sepsis

by Dijoia B. Darden, Lauren S. Kelly, Brittany P. Fenner, Lyle L. Moldawer, Alicia M. Mohr, Philip A. Efron
Published 2021-04-01

Immunological Endotyping of Chronic Critical Illness After Severe Sepsis

by Brittany P. Fenner, D. B. Darden, Lauren S. Kelly, Jaimar Rincon, Scott C. Brakenridge, Shawn D. Larson, Frederick A. Moore, Philip A. Efron, Lyle L. Moldawer
Published 2021-02-01

Unique transcriptomic response to sepsis is observed among patients of different age groups.

by Steven L Raymond, María Cecilia López, Henry V Baker, Shawn D Larson, Philip A Efron, Timothy E Sweeney, Purvesh Khatri, Lyle L Moldawer, James L Wynn
Published 2017-01-01

Phenotypic heterogeneity by site of infection in surgical sepsis: a prospective longitudinal study

by Julie A. Stortz, Michael C. Cox, Russell B. Hawkins, Gabriela L. Ghita, Babette A. Brumback, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron, Scott C. Brakenridge, Frederick A. Moore
Published 2020-05-01

Chronic Critical Illness and the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome

by Russell B. Hawkins, Steven L. Raymond, Julie A. Stortz, Hiroyuki Horiguchi, Scott C. Brakenridge, Anna Gardner, Philip A. Efron, Azra Bihorac, Azra Bihorac, Mark Segal, Mark Segal, Frederick A. Moore, Lyle L. Moldawer
Published 2018-07-01

The impact of hindlimb disuse on sepsis‐induced myopathy in mice

by Orlando Laitano, Jose Pindado, Isela Valera, Ray A. Spradlin, Kevin O. Murray, Katelyn R. Villani, Jamal M. Alzahrani, Terence E. Ryan, Philip A. Efron, Leonardo F. Ferreira, Elisabeth R. Barton, Thomas L. Clanton
Published 2021-07-01

Prognostic value of NT-proBNP levels in the acute phase of sepsis on lower long-term physical function and muscle strength in sepsis survivors

by Carlo Custodero, Quran Wu, Gabriela L. Ghita, Stephen D. Anton, Scott C. Brakenridge, Babette A. Brumback, Philip A. Efron, Anna K. Gardner, Christiaan Leeuwenburgh, Lyle L. Moldawer, John W. Petersen, Frederick A. Moore, Robert T. Mankowski
Published 2019-06-01

Host responses to sepsis vary in different low-lethality murine models.

by Lori F Gentile, Dina C Nacionales, M Cecilia Lopez, Erin Vanzant, Angela Cuenca, Benjamin E Szpila, Alex G Cuenca, Anna Joseph, Frederick A Moore, Christiaan Leeuwenburgh, Henry V Baker, Lyle L Moldawer, Philip A Efron
Published 2014-01-01

A road map from single-cell transcriptome to patient classification for the immune response to trauma

by Tianmeng Chen, Matthew J. Delano, Kong Chen, Jason L. Sperry, Rami A. Namas, Ashley J. Lamparello, Meihong Deng, Julia Conroy, Lyle L. Moldawer, Philip A. Efron, Patricia Loughran, Christopher Seymour, Derek C. Angus, Yoram Vodovotz, Wei Chen, Timothy R. Billiar
Published 2021-01-01

Machine Learning Applications in Solid Organ Transplantation and Related Complications

by Jeremy A. Balch, Daniel Delitto, Patrick J. Tighe, Patrick J. Tighe, Patrick J. Tighe, Ali Zarrinpar, Philip A. Efron, Parisa Rashidi, Parisa Rashidi, Parisa Rashidi, Parisa Rashidi, Gilbert R. Upchurch, Azra Bihorac, Azra Bihorac, Tyler J. Loftus, Tyler J. Loftus
Published 2021-09-01

Successful implementation of a packed red blood cell and fresh frozen plasma transfusion protocol in the surgical intensive care unit.

by Benjamin E Szpila, Tezcan Ozrazgat-Baslanti, Jianyi Zhang, Jennifer Lanz, Ruth Davis, Annette Rebel, Erin Vanzant, Lori F Gentile, Alex G Cuenca, Darwin N Ang, Huazhi Liu, Lawrence Lottenberg, Peggy Marker, Marc Zumberg, Azra Bihorac, Frederick A Moore, Scott Brakenridge, Philip A Efron
Published 2015-01-01

A Novel Single Cell RNA-seq Analysis of Non-Myeloid Circulating Cells in Late Sepsis

by Dijoia B. Darden, Xiaoru Dong, Maigan A. Brusko, Lauren Kelly, Brittany Fenner, Jaimar C. Rincon, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Marie Gauthier, Michael Kladde, Todd M. Brusko, Azra Bihorac, Frederick A. Moore, Tyler Loftus, Rhonda Bacher, Lyle L. Moldawer, Alicia M. Mohr, Philip A. Efron
Published 2021-08-01

Innate Immunity in the Persistent Inflammation, Immunosuppression, and Catabolism Syndrome and Its Implications for Therapy

by Hiroyuki Horiguchi, Hiroyuki Horiguchi, Tyler J. Loftus, Russell B. Hawkins, Steven L. Raymond, Julie A. Stortz, McKenzie K. Hollen, Brett P. Weiss, Elizabeth S. Miller, Azra Bihorac, Shawn D. Larson, Alicia M. Mohr, Scott C. Brakenridge, Hironori Tsujimoto, Hideki Ueno, Frederick A. Moore, Lyle L. Moldawer, Philip A. Efron, The Sepsis and Critical Illness Research Center Investigators
Published 2018-04-01

Chronic Critical Illness Elicits a Unique Circulating Leukocyte Transcriptome in Sepsis Survivors

by Dijoia B. Darden, Gabriela L. Ghita, Zhongkai Wang, Julie A. Stortz, Maria-Cecilia Lopez, Michael C. Cox, Russell B. Hawkins, Jaimar C. Rincon, Lauren S. Kelly, Brittany P. Fenner, Tezcan Ozrazgat-Baslanti, Christiaan Leeuwenburgh, Azra Bihorac, Tyler J. Loftus, Frederick A. Moore, Scott C. Brakenridge, Henry V. Baker, Rhonda Bacher, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron
Published 2021-07-01

Identification of Unique mRNA and miRNA Expression Patterns in Bone Marrow Hematopoietic Stem and Progenitor Cells After Trauma in Older Adults

by Dijoia B. Darden, Julie A. Stortz, McKenzie K. Hollen, Michael C. Cox, Camille G. Apple, Russell B. Hawkins, Jaimar C. Rincon, Maria-Cecilia Lopez, Zhongkai Wang, Eduardo Navarro, Jennifer E. Hagen, Hari K. Parvataneni, Maigan A. Brusko, Michael Kladde, Rhonda Bacher, Babette A. Brumback, Scott C. Brakenridge, Henry V. Baker, Christopher R. Cogle, Alicia M. Mohr, Philip A. Efron
Published 2020-06-01

Myeloid-derived suppressor cell function and epigenetic expression evolves over time after surgical sepsis

by McKenzie K. Hollen, Julie A. Stortz, Dijoia Darden, Marvin L. Dirain, Dina C. Nacionales, Russell B. Hawkins, Michael C. Cox, Maria-Cecilia Lopez, Jaimar C. Rincon, Ricardo Ungaro, Zhongkai Wang, Quran Wu, Babette Brumback, Marie-Pierre L. Gauthier, Michael Kladde, Christiaan Leeuwenburgh, Mark Segal, Azra Bihorac, Scott Brakenridge, Frederick A. Moore, Henry V. Baker, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron
Published 2019-11-01