SARS-CoV-2 Viral RNA Shedding for More Than 87 Days in an Individual With an Impaired CD8+ T Cell Response

by Jackson S. Turner, Aaron Day, Wafaa B. Alsoussi, Zhuoming Liu, Jane A. O’Halloran, Rachel M. Presti, Bruce K. Patterson, Sean P. J. Whelan, Ali H. Ellebedy, Philip A. Mudd
Published 2021-01-01

Acute phase CD8+ T lymphocytes against alternate reading frame epitopes select for rapid viral escape during SIV infection.

by Andrew D Walsh, Benjamin N Bimber, Arpita Das, Shari M Piaskowski, Eva G Rakasz, Alexander T Bean, Philip A Mudd, Adam J Ericsen, Nancy A Wilson, Austin L Hughes, David H O'Connor, Nicholas J Maness
Published 2013-01-01

Circulating mitochondrial DNA is an early indicator of severe illness and mortality from COVID-19

by Davide Scozzi, Marlene Cano, Lina Ma, Dequan Zhou, Ji Hong Zhu, Jane A. O’Halloran, Charles Goss, Adriana M. Rauseo, Zhiyi Liu, Sanjaya K. Sahu, Valentina Peritore, Monica Rocco, Alberto Ricci, Rachele Amodeo, Laura Aimati, Mohsen Ibrahim, Ramsey Hachem, Daniel Kreisel, Philip A. Mudd, Hrishikesh S. Kulkarni, Andrew E. Gelman
Published 2021-02-01

Interleukin-6 Trajectory and Secondary Infections in Mechanically Ventilated Patients With Coronavirus Disease 2019 Acute Respiratory Distress Syndrome Treated With Interleukin-6 R...

by M. Cristina Vazquez Guillamet, MD, Hrishikesh S. Kulkarni, MD, MSCI, Kevin Montes, MD, Maanasi Samant, MD, Preet A. Shaikh, MD, Kevin Betthauser, PharmD, Philip A. Mudd, MD, PhD, Daniel Reynolds, MD, Jane O’Halloran, MD, PhD, Patrick Lyons, MD, Colleen McEvoy, MD, Rodrigo Vazquez Guillamet, MD
Published 2021-02-01

Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections

by Kenneth E. Remy, Monty Mazer, David A. Striker, Ali H. Ellebedy, Andrew H. Walton, Jacqueline Unsinger, Teresa M. Blood, Philip A. Mudd, Daehan J. Yi, Daniel A. Mannion, Dale F. Osborne, R. Scott Martin, Nitin J. Anand, James P. Bosanquet, Jane Blood, Anne M. Drewry, Charles C. Caldwell, Isaiah R. Turnbull, Scott C. Brakenridge, Lyle L. Moldwawer, Richard S. Hotchkiss
Published 2021-02-01

CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14

by Bruce K. Patterson, Harish Seethamraju, Kush Dhody, Michael J. Corley, Kazem Kazempour, Jay Lalezari, Alina P.S. Pang, Christopher Sugai, Eisa Mahyari, Edgar B. Francisco, Amruta Pise, Hallison Rodrigues, Helen L. Wu, Gabriela M. Webb, Byung S. Park, Scott Kelly, Nader Pourhassan, Alina Lelic, Lama Kdouh, Monica Herrera, Eric Hall, Benjamin N. Bimber, Matthew Plassmeyer, Raavi Gupta, Oral Alpan, Jane A. O’Halloran, Philip A. Mudd, Enver Akalin, Lishomwa C. Ndhlovu, Jonah B. Sacha
Published 2021-02-01