The Importance of First Impressions: Early Events in Mycobacterium tuberculosis Infection Influence Outcome

by Anthony M. Cadena, JoAnne L. Flynn, Sarah M. Fortune
Published 2016-05-01

Bacterial Genome-Wide Association Identifies Novel Factors That Contribute to Ethionamide and Prothionamide Susceptibility in Mycobacterium tuberculosis

by Nathan D. Hicks, Allison F. Carey, Jian Yang, Yanlin Zhao, Sarah M. Fortune
Published 2019-04-01

The ESX system in Bacillus subtilis mediates protein secretion.

by Laura A Huppert, Talia L Ramsdell, Michael R Chase, David A Sarracino, Sarah M Fortune, Briana M Burton
Published 2014-01-01

A Mycobacterium tuberculosis Specific IgG3 Signature of Recurrent Tuberculosis

by Stephanie Fischinger, Stephanie Fischinger, Deniz Cizmeci, Deniz Cizmeci, Sally Shin, Leela Davies, Patricia S. Grace, Aida Sivro, Aida Sivro, Nonhlanhla Yende-Zuma, Nonhlanhla Yende-Zuma, Hendrik Streeck, Sarah M. Fortune, Sarah M. Fortune, Douglas A. Lauffenburger, Kogieleum Naidoo, Kogieleum Naidoo, Galit Alter
Published 2021-09-01

DNA methylation impacts gene expression and ensures hypoxic survival of Mycobacterium tuberculosis.

by Scarlet S Shell, Erin G Prestwich, Seung-Hun Baek, Rupal R Shah, Christopher M Sassetti, Peter C Dedon, Sarah M Fortune
Published 2013-01-01

Protein complexes and proteolytic activation of the cell wall hydrolase RipA regulate septal resolution in mycobacteria.

by Michael C Chao, Karen J Kieser, Shoko Minami, Daniela Mavrici, Bree B Aldridge, Sarah M Fortune, Tom Alber, Eric J Rubin
Published 2013-02-01

NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis.

by Amit K Pandey, Yibin Yang, Zhaozhao Jiang, Sarah M Fortune, Francois Coulombe, Marcel A Behr, Katherine A Fitzgerald, Christopher M Sassetti, Michelle A Kelliher
Published 2009-07-01

Correction: TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities.

by Allison F Carey, Jeremy M Rock, Inna V Krieger, Michael R Chase, Marta Fernandez-Suarez, Sebastien Gagneux, James C Sacchettini, Thomas R Ioerger, Sarah M Fortune
Published 2019-06-01

TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities.

by Allison F Carey, Jeremy M Rock, Inna V Krieger, Michael R Chase, Marta Fernandez-Suarez, Sebastien Gagneux, James C Sacchettini, Thomas R Ioerger, Sarah M Fortune
Published 2018-03-01

The Capacity of Mycobacterium tuberculosis To Survive Iron Starvation Might Enable It To Persist in Iron-Deprived Microenvironments of Human Granulomas

by Krishna Kurthkoti, Hamel Amin, Mohlopheni J. Marakalala, Saleena Ghanny, Selvakumar Subbian, Alexandra Sakatos, Jonathan Livny, Sarah M. Fortune, Michael Berney, G. Marcela Rodriguez, Christina L. Stallings
Published 2017-08-01

A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis

by Cara C Boutte, Christina E Baer, Kadamba Papavinasasundaram, Weiru Liu, Michael R Chase, Xavier Meniche, Sarah M Fortune, Christopher M Sassetti, Thomas R Ioerger, Eric J Rubin
Published 2016-06-01

EspA acts as a critical mediator of ESX1-dependent virulence in Mycobacterium tuberculosis by affecting bacterial cell wall integrity.

by Alejandra Garces, Krishnamohan Atmakuri, Michael R Chase, Joshua S Woodworth, Bryan Krastins, Alissa C Rothchild, Talia L Ramsdell, Mary F Lopez, Samuel M Behar, David A Sarracino, Sarah M Fortune
Published 2010-06-01

Digitally Barcoding Mycobacterium tuberculosis Reveals In Vivo Infection Dynamics in the Macaque Model of Tuberculosis

by Constance J. Martin, Anthony M. Cadena, Vivian W. Leung, Philana Ling Lin, Pauline Maiello, Nathan Hicks, Michael R. Chase, JoAnne L. Flynn, Sarah M. Fortune, Christina L. Stallings
Published 2017-05-01

Mutations in dnaA and a cryptic interaction site increase drug resistance in Mycobacterium tuberculosis.

by Nathan D Hicks, Samantha R Giffen, Peter H Culviner, Michael C Chao, Charles L Dulberger, Qingyun Liu, Sydney Stanley, Jessica Brown, Jaimie Sixsmith, Ian D Wolf, Sarah M Fortune
Published 2020-11-01

Mycobacterium tuberculosis-specific CD4+ and CD8+ T cells differ in their capacity to recognize infected macrophages.

by Jason D Yang, Daniel Mott, Rujapak Sutiwisesak, Yu-Jung Lu, Fiona Raso, Britni Stowell, Greg Hunter Babunovic, Jinhee Lee, Steve M Carpenter, Sing Sing Way, Sarah M Fortune, Samuel M Behar
Published 2018-02-01

A natural polymorphism of Mycobacterium tuberculosis in the esxH gene disrupts immunodomination by the TB10.4-specific CD8 T cell response.

by Rujapak Sutiwisesak, Nathan D Hicks, Shayla Boyce, Kenan C Murphy, Kadamba Papavinasasundaram, Stephen M Carpenter, Julie Boucau, Neelambari Joshi, Sylvie Le Gall, Sarah M Fortune, Christopher M Sassetti, Samuel M Behar
Published 2020-10-01

Antibody Subclass and Glycosylation Shift Following Effective TB Treatment

by Patricia S. Grace, Patricia S. Grace, Sepideh Dolatshahi, Lenette L. Lu, Adam Cain, Fabrizio Palmieri, Linda Petrone, Sarah M. Fortune, Tom H. M. Ottenhoff, Douglas A. Lauffenburger, Delia Goletti, Simone A. Joosten, Galit Alter
Published 2021-07-01

Phosphorylation of the Peptidoglycan Synthase PonA1 Governs the Rate of Polar Elongation in Mycobacteria.

by Karen J Kieser, Cara C Boutte, Jemila C Kester, Christina E Baer, Amy K Barczak, Xavier Meniche, Michael C Chao, E Hesper Rego, Christopher M Sassetti, Sarah M Fortune, Eric J Rubin
Published 2015-06-01

SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis.

by Collin R Diedrich, Tara Rutledge, Pauline Maiello, Tonilynn M Baranowski, Alexander G White, H Jacob Borish, Paul Karell, Forrest Hopkins, Jessica Brown, Sarah M Fortune, JoAnne L Flynn, Zandrea Ambrose, Philana Ling Lin
Published 2020-07-01

Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis

by Bryan D. Bryson, Tracy R. Rosebrock, Fikadu G. Tafesse, Christopher Y. Itoh, Armel Nibasumba, Gregory H. Babunovic, Bjorn Corleis, Constance Martin, Caroline Keegan, Priscila Andrade, Susan Realegeno, Douglas Kwon, Robert L. Modlin, Sarah M. Fortune
Published 2019-05-01