Metabolism fine-tunes macrophage activation

by AnnMarie Torres, Liza Makowski, Kathryn E Wellen
Published 2016-02-01

Sexual dimorphism in the hepatic protein response to a moderate trans fat diet in senescence-accelerated mice

by Steven A. Bloomer, Kathryn E. Wellen, Gregory C. Henderson
Published 2017-12-01

Compartmentalised acyl-CoA metabolism and roles in chromatin regulation

by Sophie Trefely, Claudia D. Lovell, Nathaniel W. Snyder, Kathryn E. Wellen
Published 2020-08-01

ATM Couples Replication Stress and Metabolic Reprogramming during Cellular Senescence

by Katherine M. Aird, Andrew J. Worth, Nathaniel W. Snyder, Joyce V. Lee, Sharanya Sivanand, Qin Liu, Ian A. Blair, Kathryn E. Wellen, Rugang Zhang
Published 2015-05-01

Quantification of lactoyl-CoA (lactyl-CoA) by liquid chromatography mass spectrometry in mammalian cells and tissues

by Erika L. Varner, Sophie Trefely, David Bartee, Eliana von Krusenstiern, Luke Izzo, Carmen Bekeova, Roddy S. O'Connor, Erin L. Seifert, Kathryn E. Wellen, Jordan L. Meier, Nathaniel W. Snyder
Published 2020-09-01

Subcellular metabolic pathway kinetics are revealed by correcting for artifactual post harvest metabolism

by Sophie Trefely, Joyce Liu, Katharina Huber, Mary T. Doan, Helen Jiang, Jay Singh, Eliana von Krusenstiern, Anna Bostwick, Peining Xu, Juliane G. Bogner-Strauss, Kathryn E. Wellen, Nathaniel W. Snyder
Published 2019-12-01

Pancreatic cancers suppress negative feedback of glucose transport to reprogram chromatin for metastasis

by Matthew E. Bechard, Rana Smalling, Akimasa Hayashi, Yi Zhong, Anna E. Word, Sydney L. Campbell, Amanda V. Tran, Vivian L. Weiss, Christine Iacobuzio-Donahue, Kathryn E. Wellen, Oliver G. McDonald
Published 2020-08-01

Adipocyte ACLY Facilitates Dietary Carbohydrate Handling to Maintain Metabolic Homeostasis in Females

by Sully Fernandez, John M. Viola, AnnMarie Torres, Martina Wallace, Sophie Trefely, Steven Zhao, Hayley C. Affronti, Jivani M. Gengatharan, David A. Guertin, Nathaniel W. Snyder, Christian M. Metallo, Kathryn E. Wellen
Published 2019-05-01

Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

by Keerthana Gnanapradeepan, Julia I-Ju Leu, Subhasree Basu, Thibaut Barnoud, Madeline Good, Joyce V Lee, William J Quinn, Che-Pei Kung, Rexford Ahima, Joseph A Baur, Kathryn E Wellen, Qin Liu, Zachary T Schug, Donna L George, Maureen E Murphy
Published 2020-11-01

The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development

by Wen-Yu Hsiao, Su Myung Jung, Yuefeng Tang, John A. Haley, Rui Li, Huawei Li, Camila Martinez Calejman, Joan Sanchez-Gurmaches, Chien-Min Hung, Amelia K. Luciano, Victoria DeMambro, Kathryn E. Wellen, Clifford J. Rosen, Lihua Julie Zhu, David A. Guertin
Published 2020-10-01

ATP-Citrate Lyase Controls a Glucose-to-Acetate Metabolic Switch

by Steven Zhao, AnnMarie Torres, Ryan A. Henry, Sophie Trefely, Martina Wallace, Joyce V. Lee, Alessandro Carrer, Arjun Sengupta, Sydney L. Campbell, Yin-Ming Kuo, Alexander J. Frey, Noah Meurs, John M. Viola, Ian A. Blair, Aalim M. Weljie, Christian M. Metallo, Nathaniel W. Snyder, Andrew J. Andrews, Kathryn E. Wellen
Published 2016-10-01

Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques

by Jeroen Baardman, Sanne G. S. Verberk, Saskia van der Velden, Marion J. J. Gijbels, Cindy P. P. A. van Roomen, Judith C. Sluimer, Jelle Y. Broos, Guillermo R. Griffith, Koen H. M. Prange, Michel van Weeghel, Soufyan Lakbir, Douwe Molenaar, Elisa Meinster, Annette E. Neele, Gijs Kooij, Helga E. de Vries, Esther Lutgens, Kathryn E. Wellen, Menno P. J. de Winther, Jan Van den Bossche
Published 2020-12-01