The Microbiome-Mitochondria Dance in Prodromal Parkinson’s Disease

by Sandra M. Cardoso, Sandra M. Cardoso, Nuno Empadinhas
Published 2018-05-01

Mitochondrial Fusion/Fission, Transport and Autophagy in Parkinson's Disease: When Mitochondria Get Nasty

by Daniela M. Arduíno, A. Raquel Esteves, Sandra M. Cardoso
Published 2011-01-01

Cross-talk between mitochondria and proteasome in Parkinson's disease pathogenesis

by Diogo Martins Branco, Diogo Martins Branco, Daniela M Arduino, A. Raquel Esteves, Diana F F Silva, Sandra M Cardoso, Sandra M Cardoso, Catarina Oliveira, Catarina Oliveira
Published 2010-05-01

New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer’s Disease

by Rajeshwari Rajeshwari, Karam Chand, Emanuel Candeias, Sandra M. Cardoso, Sílvia Chaves, M. Amélia Santos
Published 2019-02-01

Dysfunctional mitochondria uphold calpain activation: Contribution to Parkinson's disease pathology

by A. Raquel Esteves, Daniela M. Arduíno, Russell H. Swerdlow, Catarina R. Oliveira, Sandra M. Cardoso
Published 2010-03-01

Cyanide preconditioning protects brain endothelial and NT2 neuron-like cells against glucotoxicity: Role of mitochondrial reactive oxygen species and HIF-1α

by Sónia C. Correia, Renato X. Santos, Sandra M. Cardoso, Maria S. Santos, Catarina R. Oliveira, Paula I. Moreira
Published 2012-01-01

Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer’s drug candidates

by Luca Piemontese, Daniel Tomás, Asha Hiremathad, Vito Capriati, Emanuel Candeias, Sandra M. Cardoso, Sílvia Chaves, M. Amélia Santos
Published 2018-01-01

Novel Donepezil–Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer’s Disease

by Fausto Queda, Sónia Calò, Karolina Gwizdala, João D. Magalhães, Sandra M. Cardoso, Sílvia Chaves, Luca Piemontese, M. Amélia Santos
Published 2021-03-01

Novel tacrine–benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer’s Disease

by Gaia Fancellu, Karam Chand, Daniel Tomás, Elisabetta Orlandini, Luca Piemontese, Diana F. Silva, Sandra M. Cardoso, Sílvia Chaves, M. Amélia Santos
Published 2020-01-01

Microbial BMAA elicits mitochondrial dysfunction, innate immunity activation, and Alzheimer’s disease features in cortical neurons

by Diana F. Silva, Emanuel Candeias, A. Raquel Esteves, João D. Magalhães, I. Luísa Ferreira, Daniela Nunes-Costa, A. Cristina Rego, Nuno Empadinhas, Sandra M. Cardoso
Published 2020-11-01

Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer’s Disease Agents

by Viviana Poliseno, Sílvia Chaves, Leonardo Brunetti, Fulvio Loiodice, Antonio Carrieri, Antonio Laghezza, Paolo Tortorella, João D. Magalhães, Sandra M. Cardoso, M. Amélia Santos, Luca Piemontese
Published 2021-01-01

Structural and Functional Alterations in Mitochondria-Associated Membranes (MAMs) and in Mitochondria Activate Stress Response Mechanisms in an In Vitro Model of Alzheimer’s Diseas...

by Tânia Fernandes, Rosa Resende, Diana F. Silva, Ana P. Marques, Armanda E. Santos, Sandra M. Cardoso, M. Rosário Domingues, Paula I. Moreira, Cláudia F. Pereira
Published 2021-07-01

Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease

by Sílvia Chaves, Simonetta Resta, Federica Rinaldo, Marina Costa, Romane Josselin, Karolina Gwizdala, Luca Piemontese, Vito Capriati, A. Raquel Pereira-Santos, Sandra M. Cardoso, M. Amélia Santos
Published 2020-02-01