New Multitarget Hybrids Bearing Tacrine and Phenylbenzothiazole Motifs as Potential Drug Candidates for Alzheimer’s Disease

by Rajeshwari Rajeshwari, Karam Chand, Emanuel Candeias, Sandra M. Cardoso, Sílvia Chaves, M. Amélia Santos
Published 2019-02-01

Deep Eutectic Solvents as Effective Reaction Media for the Synthesis of 2-Hydroxyphenylbenzimidazole-Based Scaffolds en Route to Donepezil-Like Compounds

by Luca Piemontese, Roberta Sergio, Federica Rinaldo, Leonardo Brunetti, Filippo M. Perna, M. Amélia Santos, Vito Capriati
Published 2020-01-01

Donepezil structure-based hybrids as potential multifunctional anti-Alzheimer’s drug candidates

by Luca Piemontese, Daniel Tomás, Asha Hiremathad, Vito Capriati, Emanuel Candeias, Sandra M. Cardoso, Sílvia Chaves, M. Amélia Santos
Published 2018-01-01

Novel Donepezil–Arylsulfonamide Hybrids as Multitarget-Directed Ligands for Potential Treatment of Alzheimer’s Disease

by Fausto Queda, Sónia Calò, Karolina Gwizdala, João D. Magalhães, Sandra M. Cardoso, Sílvia Chaves, Luca Piemontese, M. Amélia Santos
Published 2021-03-01

Novel tacrine–benzofuran hybrids as potential multi-target drug candidates for the treatment of Alzheimer’s Disease

by Gaia Fancellu, Karam Chand, Daniel Tomás, Elisabetta Orlandini, Luca Piemontese, Diana F. Silva, Sandra M. Cardoso, Sílvia Chaves, M. Amélia Santos
Published 2020-01-01

Derivatives of Tenuazonic Acid as Potential New Multi-Target Anti-Alzheimer’s Disease Agents

by Viviana Poliseno, Sílvia Chaves, Leonardo Brunetti, Fulvio Loiodice, Antonio Carrieri, Antonio Laghezza, Paolo Tortorella, João D. Magalhães, Sandra M. Cardoso, M. Amélia Santos, Luca Piemontese
Published 2021-01-01

Design, Synthesis, and In Vitro Evaluation of Hydroxybenzimidazole-Donepezil Analogues as Multitarget-Directed Ligands for the Treatment of Alzheimer’s Disease

by Sílvia Chaves, Simonetta Resta, Federica Rinaldo, Marina Costa, Romane Josselin, Karolina Gwizdala, Luca Piemontese, Vito Capriati, A. Raquel Pereira-Santos, Sandra M. Cardoso, M. Amélia Santos
Published 2020-02-01